A highly sensitive fluorescence assay for methyltransferase activity by exonuclease-aided signal amplification

The Analyst ◽  
2015 ◽  
Vol 140 (13) ◽  
pp. 4636-4641 ◽  
Author(s):  
Feng Tang ◽  
Xi-Wen Xing ◽  
Jie-Mei Chu ◽  
Quan Yuan ◽  
Xiang Zhou ◽  
...  

A highly sensitive fluorescence assay for DNA adenine methyltransferase activity was developed using exonuclease-aided signal amplification.

2016 ◽  
Vol 781 ◽  
pp. 304-309 ◽  
Author(s):  
Jiawan Zhou ◽  
Xiaohua Zhang ◽  
Erhu Xiong ◽  
Peng Yu ◽  
Xiaoyu Li ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (4) ◽  
pp. 1219-1226 ◽  
Author(s):  
Jingjing Zhang ◽  
Chunyuan Song ◽  
Huiling Zhou ◽  
Juan Jia ◽  
Yinna Dai ◽  
...  

A dual signal amplification strategy comprising target-triggered recycling and DSN-mediated amplifications was designed and proposed for a highly sensitive fluorescence assay of nucleic acids.


The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.


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