A highly sensitive DNA sensor for attomolar detection of the BRCA1 gene: signal amplification with gold nanoparticle clusters

The Analyst ◽  
2015 ◽  
Vol 140 (8) ◽  
pp. 2713-2718 ◽  
Author(s):  
P. Abdul Rasheed ◽  
N. Sandhyarani
Keyword(s):  
Gold Nanoparticle ◽  
Signal Amplification ◽  
Brca1 Gene ◽  
Dna Sensor ◽  
Electrochemical Dna Sensor ◽  
Highly Sensitive ◽  
Nanoparticle Clusters

Gold nanoparticle clusters were successfully implemented signal amplification in an electrochemical DNA sensor.

Signal-on impedimetric electrochemical DNA sensor using dithiothreitol modified gold nanoparticle tag for highly sensitive DNA detection

2013 ◽  
Vol 799 ◽  
pp. 36-43 ◽  
Author(s):  
Cuiping Wang ◽  
Xiaqing Yuan ◽  
Xuhui Liu ◽  
Qiang Gao ◽  
Honglan Qi ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Dna Detection ◽  
Dna Sensor ◽  
Electrochemical Dna Sensor ◽  
Highly Sensitive

Electrochemical DNA sensor for specific detection of picomolar Hg(ii) based on exonuclease III-assisted recycling signal amplification

The Analyst ◽  
2015 ◽  
Vol 140 (6) ◽  
pp. 2029-2036 ◽  
Author(s):  
Xiaorong Gan ◽  
Huimin Zhao ◽  
Shuo Chen ◽  
Xie Quan
Keyword(s):  
Coordination Chemistry ◽  
Signal Amplification ◽  
Quantitative Detection ◽  
Dna Sensor ◽  
Specific Detection ◽  
Exonuclease Iii ◽  
Electrochemical Dna Sensor

An ultrasensitive methodology was successfully developed for the quantitative detection of picomolar Hg2+ based on the combination of thymine–Hg2+–thymine (T–Hg2+–T) coordination chemistry and exonuclease III-aided recycling signal amplification.

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