Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid

2015 ◽  
Vol 3 (6) ◽  
pp. 959-963 ◽  
Author(s):  
Chandrani Pramanik ◽  
Tianda Wang ◽  
Sushanta Ghoshal ◽  
Lina Niu ◽  
Bradley A. Newcomb ◽  
...  

Release of bone-bound bisphosphonates by borate bioactive glass dressings may be useful for managing bisphosphonate-related osteonecrosis of the jaw (BRONJ).

2006 ◽  
Vol 309-311 ◽  
pp. 333-336
Author(s):  
Emiko Amaoka ◽  
Erik Vedel ◽  
Satoshi Nakamura ◽  
Yusuke Moriyoshi ◽  
Jukka I. Salonen ◽  
...  

We investigated the electrical polarizability of MgO and B2O3 containing bioactive glass (MBG). The MBG material with good manufacturing properties but low bioactivity was electrically polarized at a high dc field. The electrical polarizability of MBG was evaluated by thermally stimulated depolarization current (TSDC) measurements and immersion in simulated body fluid (SBF). The early precipitation of calcium phosphate on the negatively charged surface of the treated MBG demonstrated the increased bioactivity of the material and confirmed its polarizability. It is suggested that the electrical interactions between the polarized MBG and ions in SBF promoted the formation of the calcium phosphate precipitation. Accordingly, the increased bioactivity of the MBG in SBF is suggested to demonstrate the conversion of MBG into electrovector ceramics by the polarization treatment.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
U. Boonyang ◽  
F. Li ◽  
A. Stein

In this study, bioactive glass particles with controllable structure and porosity were prepared using dual-templating methods. Block copolymers used as one template component produced mesopores in the calcined samples. Polymer colloidal crystals as the other template component yielded either three-dimensionally ordered macroporous (3DOM) products or shaped bioactive glass nanoparticles. Thein vitrobioactivity of these bioactive glasses was studied by soaking the samples in simulated body fluid (SBF) at body temperature (37°C) for varying lengths of time and monitoring the formation of bone-like apatite on the surface of the bioactive glass. A considerable bioactivity was found that all of bioactive glass samples have the ability to induce the formation of an apatite layer on its surface when in contact with SBF. The development of bone-like apatite is faster for 3DOM bioactive glasses than for nanoparticles.


Oral Diseases ◽  
2020 ◽  
Vol 26 (8) ◽  
pp. 1706-1717
Author(s):  
Zhifei Su ◽  
Jiehang Li ◽  
Xuan Bai ◽  
Franklin R. Tay ◽  
Min Zhang ◽  
...  

2011 ◽  
Vol 99B (2) ◽  
pp. 412-419 ◽  
Author(s):  
Nathalie Ginsac ◽  
Jean-Marc Chenal ◽  
Sylvain Meille ◽  
Elodie Pacard ◽  
Rachid Zenati ◽  
...  

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Botao Song ◽  
Liang Wu ◽  
Chengtie Wu ◽  
Jiang Chang

AbstractIn this communication, hollow bioactive glass (BG) nanofibers were fabricated via a single-nozzle electrospinning method. The morphology of the prepared hollow BG nanofibers was observed by SEM and TEM, and the results showed that BG nanofibers had a continuous hollow interior. The hollow BG nanofibers were incubated in simulated body fluid (SBF) to investigate their apatitemineralization ability, and the result showed that after incubation for 6 h a flower-like apatite was observed on the surface of hollowBGnanofibers, and the Fourier transform infrared (FTIR) result further confirmed the formation of apatite. The results suggested that hollow BG nanofibers could be used for drug delivery and bone regeneration applications due to their unique hollow structure and bioactivity.


2019 ◽  
Vol 45 (14) ◽  
pp. 16893-16903 ◽  
Author(s):  
Pooja Rai ◽  
Amrendra Rai ◽  
Vijay Kumar ◽  
R.K. Chaturvedi ◽  
Vinay Kumar Singh

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