Gold and silver nanoparticle interactions with human proteins: impact and implications in biocorona formation

2015 ◽  
Vol 3 (10) ◽  
pp. 2075-2082 ◽  
Author(s):  
Abhilash Sasidharan ◽  
Jim E. Riviere ◽  
Nancy A. Monteiro-Riviere
Keyword(s):  
Cellular Uptake ◽  
Silver Nanoparticle ◽  
Nanoparticle Interactions ◽  
Human Proteins

Metallic NP interaction with human proteins, biocorona formation and their impact on cellular uptake.

Protein–Silver Nanoparticle Interactions to Colloidal Stability in Acidic Environments

Langmuir ◽  
2014 ◽  
Vol 30 (43) ◽  
pp. 12755-12764 ◽  
Author(s):  
Jui-Ting Tai ◽  
Chao-Shun Lai ◽  
Hsin-Chia Ho ◽  
Yu-Shan Yeh ◽  
Hsiao-Fang Wang ◽  
...  
Keyword(s):  
Silver Nanoparticle ◽  
Colloidal Stability ◽  
Nanoparticle Interactions ◽  
Acidic Environments

scholarly journals Emerging investigator series: characterization of silver and silver nanoparticle interactions with zinc finger peptides

2019 ◽  
Vol 6 (8) ◽  
pp. 2367-2378
Author(s):  
Grace Park ◽  
Zoe N. Amaris ◽  
Madeline K. Eiken ◽  
Karl V. Baumgartner ◽  
Kathryn A. Johnston ◽  
...  
Keyword(s):  
Zinc Finger ◽  
Silver Nanoparticle ◽  
Native Structure ◽  
Potential Toxicity ◽  
Toxicity Mechanism ◽  
Silver Nanomaterials ◽  
Nanoparticle Interactions ◽  
Finger Peptides

Zn finger peptides catalyze dissolution and agglomeration of silver nanomaterials. In turn, the nanomaterials disrupt native structure and metalation of the peptide. Disruption of Zn finger function constitutes a potential toxicity mechanism.

scholarly journals Nanoparticle interactions with live cells: Quantitative fluorescence microscopy of nanoparticle size effects

2014 ◽  
Vol 5 ◽  
pp. 2388-2397 ◽  
Author(s):  
Li Shang ◽  
Karin Nienhaus ◽  
Xiue Jiang ◽  
Linxiao Yang ◽  
Katharina Landfester ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Cellular Uptake ◽  
Live Cells ◽  
Surface Charges ◽  
Nanoparticle Interactions ◽  
Quantitative Image ◽  
Endocytic Machinery ◽  
Time Courses ◽  
Quantitative Fluorescence ◽  
Key Parameter

Engineered nanomaterials are known to enter human cells, often via active endocytosis. Mechanistic details of the interactions between nanoparticles (NPs) with cells are still not well enough understood. NP size is a key parameter that controls the endocytic mechanism and affects the cellular uptake yield. Therefore, we have systematically analyzed the cellular uptake of fluorescent NPs in the size range of 3.3–100 nm (diameter) by live cells. By using spinning disk confocal microscopy in combination with quantitative image analysis, we studied the time courses of NP association with the cell membrane and subsequent internalization. NPs with diameters of less than 10 nm were observed to accumulate at the plasma membrane before being internalized by the cells. In contrast, larger NPs (100 nm) were directly internalized without prior accumulation at the plasma membrane, regardless of their surface charges. We attribute this distinct size dependence to the requirement of a sufficiently strong local interaction of the NPs with the endocytic machinery in order to trigger the subsequent internalization.

scholarly journals Investigating Silver Nanoparticle Interactions with Quaternary Ammonium Functionalized Triblock Copolymers and Their Effect on Midblock Crystallinity

2020 ◽  
Vol 2 (11) ◽  
pp. 4914-4923
Author(s):  
Nora C. Buggy ◽  
Yifeng Du ◽  
Mei-Chen Kuo ◽  
Ryan J. Gasvoda ◽  
Soenke Seifert ◽  
...  
Keyword(s):  
Silver Nanoparticle ◽  
Quaternary Ammonium ◽  
Triblock Copolymers ◽  
Nanoparticle Interactions

Graphene–ultrasmall silver nanoparticle interactions and their effect on electronic transport and Raman enhancement

Carbon ◽  
2016 ◽  
Vol 101 ◽  
pp. 305-314 ◽  
Author(s):  
F. Jimenez-Villacorta ◽  
E. Climent-Pascual ◽  
R. Ramirez-Jimenez ◽  
J. Sanchez-Marcos ◽  
C. Prieto ◽  
...  
Keyword(s):  
Silver Nanoparticle ◽  
Electronic Transport ◽  
Nanoparticle Interactions ◽  
Raman Enhancement

Silver Nanoparticle Interactions with Surfactant-Based Household Surface Cleaners

2020 ◽  
Author(s):  
Islam M. Radwan ◽  
Phillip M. Potter ◽  
Dionysios D. Dionysiou ◽  
Souhail R. Al-Abed
Keyword(s):  
Silver Nanoparticle ◽  
Nanoparticle Interactions

scholarly journals Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape

Langmuir ◽  
2014 ◽  
Vol 30 (25) ◽  
pp. 7522-7532 ◽  
Author(s):  
Chiranjeevi Peetla ◽  
Shihua Jin ◽  
Jonathan Weimer ◽  
Adekunle Elegbede ◽  
Vinod Labhasetwar
Keyword(s):  
Cellular Uptake ◽  
Membrane Lipids ◽  
Endosomal Escape ◽  
Endosomal Membrane ◽  
Nanoparticle Interactions
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