Stem cell differentiation-induced calcium silicate cement with bacteriostatic activity

2015 ◽  
Vol 3 (4) ◽  
pp. 570-580 ◽  
Author(s):  
Shu-Ching Huang ◽  
Buor-Chang Wu ◽  
Shinn-Jyh Ding
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Calcium Phosphate ◽  
Osteogenic Differentiation ◽  
Calcium Phosphate Cement ◽  
Calcium Silicate ◽  
Stem Cell Differentiation ◽  
Bacteriostatic Activity ◽  
Calcium Silicate Cement

The calcium silicate cement (CSC) on osteogenic differentiation of hMSCs and bacteriostatic abilities was more effective than calcium phosphate cement (CPC).

scholarly journals Bacterial flagella as an osteogenic differentiation nano-promoter

2019 ◽  
Vol 4 (6) ◽  
pp. 1286-1292 ◽  
Author(s):  
Dong Li ◽  
Ye Zhu ◽  
Tao Yang ◽  
Mingying Yang ◽  
Chuanbin Mao
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Osteogenic Differentiation ◽  
Stem Cell Differentiation ◽  
Osteogenic Medium ◽  
Bacterial Flagella

Flagella detached from the surface of bacteria can promote stem cell differentiation in osteogenic medium.

scholarly journals Harnessing Wharton’s jelly stem cell differentiation into bone-like nodule on calcium phosphate substrate without osteoinductive factors

2017 ◽  
Vol 49 ◽  
pp. 575-589 ◽  
Author(s):  
S. Mechiche Alami ◽  
H. Rammal ◽  
C. Boulagnon-Rombi ◽  
F. Velard ◽  
F. Lazar ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Calcium Phosphate ◽  
Stem Cell Differentiation ◽  
Wharton’S Jelly ◽  
Wharton's Jelly

scholarly journals Topography induced stiffness alteration of stem cells influences osteogenic differentiation

2020 ◽  
Vol 8 (9) ◽  
pp. 2638-2652 ◽  
Author(s):  
Liangliang Yang ◽  
Qi Gao ◽  
Lu Ge ◽  
Qihui Zhou ◽  
Eliza M. Warszawik ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Osteogenic Differentiation ◽  
Single Cell ◽  
Cell Morphology ◽  
Stem Cell Differentiation ◽  
Cell Stiffness ◽  
Biological Processes

Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.

In Vitro Mechanical Properties of a Calcium Silicate Based Bone Void Filler

2006 ◽  
Vol 309-311 ◽  
pp. 829-832 ◽  
Author(s):  
Hakan Engqvist ◽  
S. Edlund ◽  
Gunilla Gómez-Ortega ◽  
Jesper Lööf ◽  
Leif Hermansson
Keyword(s):  
Calcium Phosphate ◽  
Flexural Strength ◽  
Calcium Phosphate Cement ◽  
Calcium Silicate ◽  
Setting Time ◽  
High Strength ◽  
Calcium Silicate Cement ◽  
Bone Void Filler ◽  
Bone Void

The objective of the paper is to investigate the mechanical and the handling properties of a novel injectable bone void filler based on calcium silicate. The orthopaedic cement based on calcium silicate was compared to a calcium phosphate cement, Norian SRS from Syntes Stratec, with regard to the working (ejection through 14 G needle) and setting time (Gillmore needles), Young’s modulus and the flexural (ASTM F-394) and compressive (ISO 9917) strength after storage in phosphate buffer saline at body temperature for time points from 1h up to 16 weeks. The calcium silicate cement is composed of a calcium silicate powder (grain size below 20 µm) that is mixed with a liquid (water and CaCl2) into a paste using a spatula and a mixing cup. The water to cement ratio used was about 0.5. The calcium silicate had a working time of 15 minutes and a setting time of 17 minutes compared to 5 and 10 minutes respectively for the calcium phosphate cement. The compressive strength was considerably higher for the calcium silicate cement (>100 MPa) compared to the calcium phosphate cement (>40 MPa). Regarding the flexural strength the calcium silicate cement had high values for up to 1 week (> 40 MPa) but it decreased to 25 MPa after 16 weeks. The phosphate cement had a constant flexural strength of about 25 MPa. The results show that calcium silicate cement has the mechanical and handling potential to be used as high strength bone void filler.

scholarly journals Synergistic acceleration in the osteogenesis of human mesenchymal stem cells by graphene oxide–calcium phosphate nanocomposites

2014 ◽  
Vol 50 (62) ◽  
pp. 8484-8487 ◽  
Author(s):  
Rameshwar Tatavarty ◽  
Hao Ding ◽  
Guijin Lu ◽  
Robert J. Taylor ◽  
Xiaohong Bi
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Graphene Oxide ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Calcium Phosphate ◽  
Synergistic Effect ◽  
Human Mesenchymal Stem Cells ◽  
Stem Cell Differentiation ◽  
Calcium Phosphate Nanoparticles

Nanocomposites consisting of oblong ultrathin plate shaped calcium phosphate nanoparticles and graphene oxide microflakes were synthesized and have demonstrated markedly synergistic effect in accelerating stem cell differentiation to osteoblasts.

Topographical regulation of stem cell differentiation by plant-derived micro/nanostructures

Nanoscale ◽  
2020 ◽  
Vol 12 (35) ◽  
pp. 18305-18312 ◽  
Author(s):  
Ruitong Zhang ◽  
Shuwei Han ◽  
Na Ren ◽  
Linlin Liang ◽  
Na Liang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Osteogenic Differentiation ◽  
Stem Cell Differentiation ◽  
Adipose Derived Stem Cells

A novel plant-derived material as scaffolds that can promote the osteogenic differentiation of human adipose-derived stem cells is reported.

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