Supercritical carbon dioxide-assisted drug loading and release from biocompatible porous metal–organic frameworks

2014 ◽  
Vol 2 (43) ◽  
pp. 7551-7558 ◽  
Author(s):  
Kiyoshi Matsuyama ◽  
Nobukatsu Hayashi ◽  
Misaki Yokomizo ◽  
Takafumi Kato ◽  
Kiyomi Ohara ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Controlled Release ◽  
Supercritical Carbon Dioxide ◽  
Drug Loading ◽  
Metal Organic Frameworks ◽  
Porous Metal ◽  
Porous Iron ◽  
Metal Organic ◽  
Supercritical Carbon

The scCO2-assisted loading of ibuprofen on nontoxic and biocompatible porous iron(iii) polycarboxylate metal–organic frameworks (MOFs) demonstrated high guest loading and controlled release of these materials.

Supercritical Carbon Dioxide Enables Rapid, Clean, and Scalable Conversion of a Metal Oxide into Zeolitic Metal–Organic Frameworks

2018 ◽  
Vol 18 (5) ◽  
pp. 3222-3228 ◽  
Author(s):  
Joseph M. Marrett ◽  
Cristina Mottillo ◽  
Simon Girard ◽  
Christopher W. Nickels ◽  
Jean-Louis Do ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Metal Oxide ◽  
Metal Organic Frameworks ◽  
Metal Organic ◽  
Supercritical Carbon

Encapsulation and controlled release of fragrances from functionalized porous metal-organic frameworks

AIChE Journal ◽  
2018 ◽  
Vol 65 (2) ◽  
pp. 491-499 ◽  
Author(s):  
Yuhang Liu ◽  
Yuxiang Wang ◽  
Jianxiang Huang ◽  
Zhuxian Zhou ◽  
Dan Zhao ◽  
...  
Keyword(s):  
Controlled Release ◽  
Metal Organic Frameworks ◽  
Porous Metal ◽  
Metal Organic

Study on the Use of Supercritical Carbon Dioxide as a Solvent to Prepare Novel, Efficient Controlled-Release Materials

2014 ◽  
Vol 71 (1) ◽  
pp. 1-10
Author(s):  
Chikara TSUTSUMI ◽  
Ami TSUZUKI ◽  
Teruyuki HARA ◽  
Yuushou NAKAYAMA ◽  
Takeshi SHIONO
Keyword(s):  
Carbon Dioxide ◽  
Controlled Release ◽  
Supercritical Carbon Dioxide ◽  
Supercritical Carbon

Selective Dual Adsorption Performance of Hexagonal Porous Metal-Organic Framework Rods towards CO2 gas and Organic Dye

2021 ◽  
Author(s):  
Hridoy Jyoti Bora ◽  
Neelotpal Sen Sarma ◽  
Anamika Kalita
Keyword(s):  
Carbon Dioxide ◽  
Present Report ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Porous Metal ◽  
Adsorption Properties ◽  
Organic Dye ◽  
Co2 Gas ◽  
Adsorption Performance ◽  
Metal Organic

Structurally diverse metal-organic frameworks (MOFs) have drawn much attention as potential adsorbent for many contaminants. Herein, the present report demonstrated the enhanced dual adsorption properties of environmentally concerned carbon dioxide...

Preparation of Liposome Particle of Atractylone by Supercritical Carbon Dioxide Process

2010 ◽  
Vol 92 ◽  
pp. 177-182 ◽  
Author(s):  
Zhen Wen ◽  
Bo Liu ◽  
Zong Kun Zheng ◽  
Xin Kui You ◽  
Yi Tao Pu ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Physicochemical Properties ◽  
Drug Loading ◽  
Entrapment Efficiency ◽  
Liposome Suspension ◽  
Liposomal Suspension ◽  
Atractylodes Macrocephala ◽  
Average Size ◽  
Supercritical Carbon

The liposome particle entrapping atractylone extracted from Atractylodes macrocephala Koidz.was prepared and characterized. The liposome suspension of atractylone was formed by supercritical carbon dioxide (SC-CO2) expansion process and was dried by vacuum freezing. The physicochemical properties of the liposome particle including microstructure, size, entrapment efficiency and drug loading content were measured. The liposome formation could be controlled by adjusting the processing conditions such as pressure, temperature of SC-CO2 and mole fraction of ethanol in SC-CO2 [ x (CH3CH2OH)]. The entrapment efficiency, loading content, and average size of liposome particle were 83.1％, 5.1％ and 506.5nm respectively under the optimum conditions of 30MPa，338K and x (CH3CH2OH) = 15％.The liposome particle presented good performance of redispersion to liposomal suspension. The physicochemical properties of liposome particle including entrapment efficiency, dissolution rate and stability complied with the provisions of Chinese pharmacopoeia. The results show the liposome particle can be used as an solid immediate for hepatic target of drugs.

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