Mechanical analysis of rat trabecular meshwork

Soft Matter ◽  
2015 ◽  
Vol 11 (14) ◽  
pp. 2857-2865 ◽  
Author(s):  
Jianyong Huang ◽  
Lucinda J. Camras ◽  
Fan Yuan
Keyword(s):  
Atomic Force Microscopy ◽  
Young’S Modulus ◽  
Trabecular Meshwork ◽  
Young's Modulus ◽  
Mechanical Analysis ◽  
Force Microscopy ◽  
Atomic Force

We developed a method to quantify the initial Young's modulus of rat trabecular meshwork (TM) in situ, based on atomic force microscopy (AFM).

Ultrasonically synthesized organic liquid-filled chitosan microcapsules: part 2: characterization using AFM (atomic force microscopy) and combined AFM–confocal laser scanning fluorescence microscopy

Soft Matter ◽  
2018 ◽  
Vol 14 (16) ◽  
pp. 3192-3201 ◽  
Author(s):  
Srinivas Mettu ◽  
Qianyu Ye ◽  
Meifang Zhou ◽  
Raymond Dagastine ◽  
Muthupandian Ashokkumar
Keyword(s):  
Atomic Force Microscopy ◽  
Fluorescence Microscopy ◽  
Young’S Modulus ◽  
Laser Scanning ◽  
Young's Modulus ◽  
Organic Liquid ◽  
Confocal Laser Scanning ◽  
Confocal Laser ◽  
Force Microscopy ◽  
Atomic Force

Atomic Force Microscopy (AFM) is used to measure the stiffness and Young's modulus of individual microcapsules that have a chitosan cross-linked shell encapsulating tetradecane.

Elastic properties and breaking strengths of GaS, GaSe and GaTe nanosheets

Nanoscale ◽  
2018 ◽  
Vol 10 (27) ◽  
pp. 13022-13027 ◽  
Author(s):  
Basant Chitara ◽  
Assaf Ya'akobovitz
Keyword(s):  
Atomic Force Microscopy ◽  
Young’S Modulus ◽  
Elastic Properties ◽  
Young's Modulus ◽  
Force Microscopy ◽  
Atomic Force ◽  
Maximal Strain

The present study highlights the elastic properties of suspended GaS, GaSe and GaTe nanosheets using atomic force microscopy. GaS exhibited the highest Young's modulus (∼173 GPa) among these nanosheets. These materials can withstand maximal stresses of up to 8 GPa and a maximal strain of 7% before breaking, making them suitable for stretchable electronic and optomechanical devices.

Young’s Modulus of Nanohoneycomb Structures According to the Porosity

2007 ◽  
Vol 334-335 ◽  
pp. 761-764
Author(s):  
D.H. Choi ◽  
C.W. Lee ◽  
P.S. Lee ◽  
J.H. Lee ◽  
W. Hwang ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Young’S Modulus ◽  
Large Range ◽  
Young's Modulus ◽  
Vertical Direction ◽  
Moment Of Inertia ◽  
Beam Length ◽  
Bending Tests ◽  
Force Microscopy ◽  
Atomic Force

Young’s modulus of nanohoneycomb structures in the vertical direction relative to the pore (generally along the beam length) is measured according to the porosity from bending tests in atomic force microscopy (AFM). The pore diameters of the nanohoneycomb structures are from about 30 to 60 nm. To determine the Young’s modulus of the nanohoneycomb structures, the area moment of inertia of the nanohoneycomb structure is determined according to the arrangement of the pores. The area moment of inertia of the nanohoneycomb structure is found to be affected by the porosity of the nanohoneycomb structures. The Young’s modulus of the nanohoneycomb structures decreases as a function of the porosity in a large range.

scholarly journals Alteration of nanomechanical properties of pancreatic cancer cells through anticancer drug treatment revealed by atomic force microscopy

2021 ◽  
Vol 12 ◽  
pp. 1372-1379
Author(s):  
Xiaoteng Liang ◽  
Shuai Liu ◽  
Xiuchao Wang ◽  
Dan Xia ◽  
Qiang Li
Keyword(s):  
Mechanical Properties ◽  
Pancreatic Cancer ◽  
Atomic Force Microscopy ◽  
Cancer Cells ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Force Microscopy ◽  
Pancreatic Cancer Cells ◽  
Atomic Force ◽  
Aggressive Cancer

The mechanical properties of cells are key to the regulation of cell activity, and hence to the health level of organisms. Here, the morphology and mechanical properties of normal pancreatic cells (HDPE6-C7) and pancreatic cancer cells (AsPC-1, MIA PaCa-2, BxPC-3) were studied by atomic force microscopy. In addition, the mechanical properties of MIA PaCa-2 after treatment with different concentrations of doxorubicin hydrochloride (DOX) were also investigated. The results show the Young's modulus of normal cells is greater than that of three kinds of cancer cells. The Young's modulus of more aggressive cancer cell AsPC-1 is smaller than that of less aggressive cancer cell BxPC-3. In addition, the Young's modulus of MIA PaCa-2 rises with the increasing of DOX concentration. This study may provide a new strategy of detecting cancer, and evaluate the possible interaction of drugs on cells.

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