Citrate modified β-cyclodextrin functionalized magnetite nanoparticles: a biocompatible platform for hydrophobic drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (28) ◽  
pp. 22117-22125 ◽  
Author(s):  
Kunnoth N. Jayaprabha ◽  
Pattayil A. Joy

Water dispersible, β-cyclodextrin functionalized, magnetite nanoparticles are shown to be suitable for the delivery of the hydrophobic drug curcumin, with possible multifunctional applications.

2007 ◽  
Vol 19 (25) ◽  
pp. 6345-6349 ◽  
Author(s):  
Shashwat S. Banerjee ◽  
Dong-Hwang Chen

RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86754-86762 ◽  
Author(s):  
Jerina Majeed ◽  
K. C. Barick ◽  
Neena G. Shetake ◽  
B. N. Pandey ◽  
P. A. Hassan ◽  
...  

Development of water-dispersible polyphosphate-grafted Fe3O4 nanomagnets for hyperthermia and drug delivery applications.


Author(s):  
Pandey Swarnima ◽  
Sushant Kumar

The paper is aimed to provide a comprehensive review on nanoparticles, methods of preparation, applications in drug delivery. In recent years, there has been an exponential interest within the development of novel drug delivery systems using nanoparticles. Nanoparticles offers significant advantages over the conventional drug delivery in terms of high stability, high specificity, high drug carrying capacity, ability for controlled release, possibility to use in several route of administration and therefore the capability to deliver both hydrophilic and hydrophobic drug molecules. This review focuses on classification, methods of preparation, characterization, application, advantages of nanoparticles and health perspectives.


2010 ◽  
Author(s):  
Claudia Nădejde ◽  
Ecaterina Foca-nici Ciurlică ◽  
Dorina Creangă ◽  
Aurelian Ca^rlescu ◽  
Vasile Bădescu ◽  
...  

RSC Advances ◽  
2018 ◽  
Vol 8 (71) ◽  
pp. 40554-40563 ◽  
Author(s):  
Meng-Meng Song ◽  
Hui-Hui Xiang ◽  
Meng-Yu Fei ◽  
Da-Peng Lu ◽  
Tong-Cui Jiang ◽  
...  

Water-dispersible, stable and biocompatible dandelion-like Fe3O4/HBC@F127 nanocomposites were facilely developed for dual mode imaging (fluorescent/MR) and drug delivery.


Pharmaceutics ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 97 ◽  
Author(s):  
Delia Mandracchia ◽  
Adriana Trapani ◽  
Sara Perteghella ◽  
Cinzia Di Franco ◽  
Maria Torre ◽  
...  

Hydrogels are among the most common materials used in drug delivery, as polymeric micelles are too. They, preferentially, load hydrophilic and hydrophobic drugs, respectively. In this paper, we thought to combine the favorable behaviors of both hydrogels and polymeric micelles with the specific aim of delivering hydrophilic and hydrophobic drugs for dual delivery in combination therapy, in particular for colon drug delivery. Thus, we developed a hydrogel by UV crosslinking of a methacrylated (MA) amphiphilic derivative from inulin (INU) (as known INU is specifically degraded into the colon) and vitamin E (VITE), called INVITEMA. The methacrylated micelles were physicochemically characterized and subjected to UV irradiation to form what we called the “nanogrids”. The INVITEMA nanogrids were characterized by DSC, SEM, TEM, water uptake and beclomethasone dipropionate (BDP) release. In particular, the release of the hydrophobic drug was specifically assessed to verify that it can spread along the hydrophilic portions and, therefore, effectively released. These systems can open new pharmaceutical applications for known hydrogels or micelle systems, considering that in literature only few examples are present.


2018 ◽  
Vol 7 (2.19) ◽  
pp. 87
Author(s):  
D BALAJ ◽  
C SARALA RUBI ◽  
N G. RENGANATHAN

Attractive nanoparticles have been broadly considered on account of their potential applications as complexity operators in attractive reverberation imaging (MRI) of tumors, cell and DNA partition, attractively guided medication conveyance, tumor hyperthermia. Among the attractive oxides, magnetite nanoparticles are most appropriate because of their low danger and great attractive properties which may be used in drug delivery. Magnetite nanoparticles were synthesized using FeCl3 and FeSO4 as precursors and characterized for size and shape using non-contact AFM.  The formation of magnetite was confirmed by XRD pattern. The elemental composition of the obtained phase was determined using EDAX. In this work, we are aiming to develop drug loaded biopolymer Magnetite nanoparticles for biomedical application. Our main objective is to synthesize and characterize Magnetite (Fe3O4) nanoparticles.  


2008 ◽  
Vol 359 (1-2) ◽  
pp. 228-233 ◽  
Author(s):  
MaLing Gou ◽  
XingYi Li ◽  
Mei Dai ◽  
ChangYang Gong ◽  
XianHuo Wang ◽  
...  

2017 ◽  
Vol 90 ◽  
pp. 13-24 ◽  
Author(s):  
Esmat Jalalvandi ◽  
Lyall R. Hanton ◽  
Stephen C. Moratti

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