Cathepsin B-sensitive cholesteryl hemisuccinate–gemcitabine prodrug nanoparticles: enhanced cellular uptake and intracellular drug controlled release

RSC Advances ◽  
2015 ◽  
Vol 5 (9) ◽  
pp. 6985-6992 ◽  
Author(s):  
Yanyun Xu ◽  
Jianqi Geng ◽  
Ping An ◽  
Yan Xu ◽  
Jin Huang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Cellular Uptake ◽  
Cathepsin B ◽  
Drug Controlled Release ◽  
Cholesteryl Hemisuccinate

Cholesteryl hemisuccinate–gemcitabine prodrug: enhanced cellular uptake and intracellular drug controlled release.

Enhanced cellular uptake and intracellular drug controlled release of VESylated gemcitabine prodrug nanocapsules

2015 ◽  
Vol 128 ◽  
pp. 357-362 ◽  
Author(s):  
Yanfen Fang ◽  
Fang Du ◽  
Yanyun Xu ◽  
Haijing Meng ◽  
Jin Huang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Cellular Uptake ◽  
Drug Controlled Release

Size changeable nanosystems for precise drug controlled release and efficient overcoming of cancer multidrug resistance

2017 ◽  
Vol 5 (5) ◽  
pp. 944-952 ◽  
Author(s):  
Xueyang Fang ◽  
Wenting Jiang ◽  
Yanyu Huang ◽  
Fang Yang ◽  
Tianfeng Chen
Keyword(s):  
Multidrug Resistance ◽  
Controlled Release ◽  
Cancer Cells ◽  
Cellular Uptake ◽  
Rational Design ◽  
Drug Controlled Release

Herein we demonstrate the rational design of a size changeable nanosystem for precise drug controlled release and efficient overcoming of cancer multidrug resistance in cancer cells by enhancing the cellular uptake and inhibiting the expression of ABC family proteins.

Antibiotic-anionic Clay Matrix Used for Drug Controlled Release

2018 ◽  
Vol 69 (2) ◽  
pp. 321-323
Author(s):  
Georgeta Zegan ◽  
Elena Mihaela Carausu ◽  
Loredana Golovcencu ◽  
Alina Sodor Botezatu ◽  
Eduard Radu Cernei ◽  
...  
Keyword(s):  
Controlled Release ◽  
Layered Double Hydroxides ◽  
Bioactive Molecules ◽  
Drug Controlled Release ◽  
Anionic Clays ◽  
Anionic Clay ◽  
Toxicological Studies ◽  
High Efficient ◽  
Clay Matrix ◽  
Double Hydroxides

Anionic clay matrix acting as drug controlled release system have shown in last years a great potential for delivery of bioactive molecules and chemical therapeutics. This organic-inorganic nanohybrid system is high efficient offering an excellent protection of intercalated compounds from degradation. Compared to other nanoparticles used in medical area, anionic clays type layered double hydroxides have found to be biocompatible according to toxicological studies. Ampicillin containing MgAlLDHs and ZnAlLDH samples have been prepared following two routes: anion-exchange procedure and reconstruction from calcined layered double hydroxides. Solid samples have been characterized by FTIR and SEM-EDX highlighting the alteration of pristine LDHs structure when the antibiotic is introduced in the interlayer gallery.

Behaviour Of Different Silica-Based Mesoporous As Matrixes For Drug Controlled Release

2010 ◽  
pp. 7-16
Author(s):  
Rosario Aiello ◽  
Ida Stefania Carino ◽  
Francesca Iemma ◽  
Luigi Pasqua ◽  
Francesco Puoci ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Controlled Release

scholarly journals Contact lenses as drug controlled release systems: a narrative review

2016 ◽  
Vol 75 ◽  
Author(s):  
Helena Prior Filipe ◽  
José Henriques ◽  
Pedro Reis ◽  
Pedro Cruz Silva ◽  
Maria João Quadrado ◽  
...  
Keyword(s):  
Controlled Release ◽  
Contact Lenses ◽  
Narrative Review ◽  
Drug Controlled Release

Investigation of magnetic silica with thermoresponsive chitosan coating for drug controlled release and magnetic hyperthermia application

2019 ◽  
Vol 97 ◽  
pp. 23-30 ◽  
Author(s):  
Weeraphat Pon-On ◽  
Tanatsaparn Tithito ◽  
Weerakanya Maneeprakorn ◽  
Tanapon Phenrat ◽  
I-Ming Tang
Keyword(s):  
Controlled Release ◽  
Magnetic Hyperthermia ◽  
Drug Controlled Release ◽  
Chitosan Coating ◽  
Magnetic Silica
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