Y-shaped block copolymer (methoxy-poly(ethylene glycol))2-b-poly(l-glutamic acid): preparation, self-assembly, and use as drug carriers

RSC Advances ◽  
2014 ◽  
Vol 4 (78) ◽  
pp. 41588-41596 ◽  
Author(s):  
Lixin Yang ◽  
Xiuli Hu ◽  
Weiqi Wang ◽  
Shi Liu ◽  
Tingting Sun ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Glutamic Acid ◽  
Solid Tumors ◽  
Self Assembly ◽  
Drug Carriers ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Polymer Drugs

The nano polymer drugs based on Y-shaped block copolymer mPEG2-PGA show a great potential on the treatment for solid tumors.

Star-shaped poly(l-lactide)-b-poly(ethylene glycol) with porphyrin core: synthesis, self-assembly, drug-release behavior and singlet oxygen research

2014 ◽  
Vol 38 (8) ◽  
pp. 3569-3578 ◽  
Author(s):  
Xiao-Hui Dai ◽  
Zhi-Ming Wang ◽  
Lu-You Gao ◽  
Jian-Ming Pan ◽  
Xiao-Hong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Release Behavior ◽  
Poly Ethylene Glycol ◽  
Drug Release Behavior ◽  
Porphyrin Core ◽  
Poly Ethylene

pH-induced block copolymer SPPLA-b-PEG with porphyrin core for photodynamic therapy.

In SituSynthesis of Block Copolymer Nanoassemblies via Polymerization-Induced Self-Assembly in Poly(ethylene glycol)

2016 ◽  
Vol 49 (10) ◽  
pp. 3789-3798 ◽  
Author(s):  
Chengqiang Gao ◽  
Heng Zhou ◽  
Yaqing Qu ◽  
Wei Wang ◽  
Habib Khan ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Copolymer Nanoparticles Prepared by Self-Assembly of Poly(ethylene glycol) and Poly-γ-Glutamic Acid and its Characteristics

2013 ◽  
Vol 662 ◽  
pp. 136-139
Author(s):  
Ge Yang ◽  
Ke Shuai Lu ◽  
Xue Yan Su
Keyword(s):  
Ethylene Glycol ◽  
Glutamic Acid ◽  
Size Distribution ◽  
Self Assembly ◽  
Aqueous Media ◽  
Poly Ethylene Glycol ◽  
Polyelectrolyte Complexes ◽  
Self Assembling ◽  
Transmission Electron ◽  
Poly Ethylene

The paper describes the preparation and characterization of novel biodegradable nanoparticles based on self-assembly of poly-gamma-glutamic acid (γ-PGA) and poly(ethylene glycol) (PEG). The nanosystems were stable in aqueous media at low pH conditions. Solubility of the systems was determined by turbidity measurements. The particle size and the size distribution of the polyelectrolyte complexes were identified by dynamic lightscattering and transmission electron microscopy.It was found that the size and size distribution of the nanosystems depends on the concentrations of γ-PGA and PEG solutions and their ratio as well as on the pH of the mixture and the order of addition. The diameter of individual particles was in the range of 30–270 nm. measured by TEM, and the average hydrodynamic diameters were between 130 and 300 nm. These biodegradable, self-assembling stable nanocomplexes might be useful for several biomedical applications.

scholarly journals Poly(ethylene glycol)-b-poly(vinyl acetate) block copolymer particles with various morphologies via RAFT/MADIX aqueous emulsion PISA

2020 ◽  
Vol 11 (23) ◽  
pp. 3922-3930
Author(s):  
Paul Galanopoulo ◽  
Pierre-Yves Dugas ◽  
Muriel Lansalot ◽  
Franck D'Agosto
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Vinyl Acetate ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Poly Ethylene Glycol ◽  
Aqueous Emulsion ◽  
Amphiphilic Diblock Copolymers ◽  
Poly Ethylene

The polymerization-induced self-assembly (PISA) of amphiphilic diblock copolymers of poly(ethylene glycol)-b-poly(vinyl acetate) in water was achieved through macromolecular design via interchange of xanthate (MADIX) polymerization in emulsion.

scholarly journals Tuning the hydroxyl functionality of block copolymer worm gels modulates their thermoresponsive behavior

2020 ◽  
Vol 11 (31) ◽  
pp. 5040-5050 ◽  
Author(s):  
Lucia Romero-Azogil ◽  
Nicholas J. W. Penfold ◽  
Steven P. Armes
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Partial Replacement ◽  
Poly Ethylene Glycol ◽  
Aqueous Polymerization ◽  
Poly Ethylene

Partial replacement of a hydroxyl-functional steric stabilizer with a poly(ethylene glycol)-based stabilizer modulates the thermoresponsive behavior of block copolymer worm gels prepared via aqueous polymerization-induced self-assembly.

scholarly journals Poly(ethylene glycol) brush-b-poly(N-vinylpyrrolidone)-based double hydrophilic block copolymer particles crosslinked via crystalline α-cyclodextrin domains

RSC Advances ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 4993-5001 ◽  
Author(s):  
Noah Al Nakeeb ◽  
Zdravko Kochovski ◽  
Tingting Li ◽  
Youjia Zhang ◽  
Yan Lu ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Poly Ethylene Glycol ◽  
Glycol Methacrylate ◽  
Oligoethylene Glycol ◽  
Poly Ethylene ◽  
Copolymer Poly

Self-assembly of the double hydrophilic block copolymer poly(N-vinylpyrrolidone)-b-poly(oligoethylene glycol methacrylate) and supramolecular crosslinking via α-cyclodextrin in water is presented.

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