Palladium catalyzed direct allylation of azlactones with simple allylic alcohols in the absence of any activators

RSC Advances ◽  
2014 ◽  
Vol 4 (49) ◽  
pp. 25596-25599 ◽  
Author(s):  
Hui Zhou ◽  
Huameng Yang ◽  
Hongyu Yin ◽  
Muwen Liu ◽  
Chungu Xia ◽  
...  
Keyword(s):  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed ◽  
Neutral Conditions

The first example of the readily scalable direct allylic alkylation of azlactones with simple allylic alcohols has been developed, which is catalyzed by Pd(PPh3)4 alone in the absence of any activators under neutral conditions.

Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study

2014 ◽  
Vol 126 (26) ◽  
pp. 6894-6898 ◽  
Author(s):  
Xiaohong Huo ◽  
Guoqiang Yang ◽  
Delong Liu ◽  
Yangang Liu ◽  
Ilya D. Gridnev ◽  
...  
Keyword(s):  
Mechanistic Study ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed

Amide Acetal in Palladium-Catalyzed Allylation with Allylic Alcohols under Neutral Conditions

2017 ◽  
Vol 6 (5) ◽  
pp. 520-526 ◽  
Author(s):  
Yongseok Kwon ◽  
Jaehyun Jung ◽  
Jae Hyun Kim ◽  
Woo-Jung Kim ◽  
Sanghee Kim
Keyword(s):  
Allylic Alcohols ◽  
Amide Acetal ◽  
Palladium Catalyzed ◽  
Neutral Conditions

ChemInform Abstract: Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study.

ChemInform ◽  
2015 ◽  
Vol 46 (1) ◽  
Author(s):  
Xiaohong Huo ◽  
Guoqiang Yang ◽  
Delong Liu ◽  
Yangang Liu ◽  
Ilya D. Gridnev ◽  
...  
Keyword(s):  
Mechanistic Study ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed

Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study

2014 ◽  
Vol 53 (26) ◽  
pp. 6776-6780 ◽  
Author(s):  
Xiaohong Huo ◽  
Guoqiang Yang ◽  
Delong Liu ◽  
Yangang Liu ◽  
Ilya D. Gridnev ◽  
...  
Keyword(s):  
Mechanistic Study ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed

Palladium-Catalyzed C-Allylation of Naphthols by Direct Use of Allylic Alcohols under Neutral Conditions

1996 ◽  
Vol 25 (12) ◽  
pp. 1021-1022 ◽  
Author(s):  
Yuzuki Tada ◽  
Akiharu Satake ◽  
Isao Shimizu ◽  
Akio Yamamoto
Keyword(s):  
Allylic Alcohols ◽  
Palladium Catalyzed ◽  
Neutral Conditions ◽  
Direct Use

Ni(0)-Catalyzed α-Allylic Alkylation of Regular Ketones with 1,3-Dienes under pH and Redox-neutral Conditions

2019 ◽  
Author(s):  
Tiantian Chen ◽  
Yang Yang ◽  
Liyu Xie ◽  
Haijian Yang ◽  
Guangbin Dong ◽  
...  
Keyword(s):  
Oxidative Addition ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Dual Role ◽  
Allylic Alkylation ◽  
Cross Coupling Reaction ◽  
Neutral Conditions

<p>We report a Ni(0)-catalyzed cross coupling reaction between simple ketones and 1,3-dienes. A variety of a-allylic alkylation products were formed in an 1,2-addition manner with excellent regioselectivity. Water was found to significantly accelerate this transformation. A HO-Ni-H species generated from oxidative addition of Ni(0) to H<sub>2</sub>O is proposed to play a “dual role” in activating both the ketone and the diene substrate.</p>

Sign in / Sign up

Export Citation Format

Share Document