Facile synthesis of 5H-benzo[b]carbazol-6-yl ketones via sequential reaction of Cu-catalyzed Friedel–Crafts alkylation, iodine-promoted cyclization, nucleophilic substitution and aromatization

2014 ◽  
Vol 12 (35) ◽  
pp. 6806-6811 ◽  
Author(s):  
Jing Wu ◽  
Dongping Wang ◽  
Haolong Wang ◽  
Fan Wu ◽  
Xincheng Li ◽  
...  
Keyword(s):  
Nucleophilic Substitution ◽  
Convenient Method ◽  
Facile Synthesis ◽  
Sequential Reaction

A convenient method to access 5H-benzo[b]carbazol-6-yl ketones from indoles and 2-(2-(alkynyl)benzylidene)malonates has been developed.

Facile synthesis of novel 3,4,5-trisubstituted-1,2,4-triazin-6(1H)-onesviaa sequential Ugi–Smiles type/nucleophilic substitution/cyclization reaction

2018 ◽  
Vol 42 (21) ◽  
pp. 17533-17537
Author(s):  
Sorour Ramezanpour ◽  
Mohammad Nasim Rezaei ◽  
Aref Vaezghaemi ◽  
Frank Rominger
Keyword(s):  
Nucleophilic Substitution ◽  
Biological Activities ◽  
Cyclization Reaction ◽  
Facile Synthesis ◽  
Innovative Strategy ◽  
Pyrimidine Bases

An innovative strategy for synthesis of a library of complex multi-substituted 1,2,4-triazine-6-ones. These structures are analogues of pyrimidine bases with possible enhanced biological activities.

Facile synthesis of 3,5-diaryl-1,2,4-triazoles via copper-catalyzed domino nucleophilic substitution/oxidative cyclization using amidines or imidates as substrates

Tetrahedron ◽  
2014 ◽  
Vol 70 (8) ◽  
pp. 1635-1645 ◽  
Author(s):  
Kavitha Sudheendran ◽  
Dietmar Schmidt ◽  
Wolfgang Frey ◽  
Jürgen Conrad ◽  
Uwe Beifuss
Keyword(s):  
Nucleophilic Substitution ◽  
Oxidative Cyclization ◽  
Facile Synthesis

The allylic nucleophilic substitution of Morita–Baylis–Hillman acetates with isocyanides: a facile synthesis of trisubstituted olefins

2010 ◽  
Vol 51 (17) ◽  
pp. 2291-2294 ◽  
Author(s):  
J.S. Yadav ◽  
B.V. Subba Reddy ◽  
Ashutosh Pratap Singh ◽  
Nilanjan Majumder
Keyword(s):  
Nucleophilic Substitution ◽  
Facile Synthesis ◽  
Trisubstituted Olefins

Regioselective nucleophilic substitution in activated 1-aminopyrazolium cations: A facile synthesis of 5-substituted 1-methylpyrazoles

1985 ◽  
Vol 26 (44) ◽  
pp. 5485-5488 ◽  
Author(s):  
Martha Bruix ◽  
M.Luisa Castellanos ◽  
M.Rosario Martín ◽  
Javier de Mendoza
Keyword(s):  
Nucleophilic Substitution ◽  
Facile Synthesis ◽  
Substituted 1
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