MALDI mass spectrometry for probing the anti- staphylococcal capability of TiO2nanoparticles via near-UV and laser irradiation

2015 ◽  
Vol 39 (6) ◽  
pp. 4909-4918 ◽  
Author(s):  
Judy Gopal ◽  
Jayaram Lakshmaiah Narayana ◽  
Nazim Hasan ◽  
Hui-Fen Wu

We report the use of MALDI-MS as an effective tool in investigating the anti-staphylococcal property of TiO2nanoparticles under near-UV and for the first time also under laser irradiation.

2020 ◽  
Vol 58 (6) ◽  
pp. 883-896 ◽  
Author(s):  
Muhammad Zubair Israr ◽  
Dennis Bernieh ◽  
Andrea Salzano ◽  
Shabana Cassambai ◽  
Yoshiyuki Yazaki ◽  
...  

AbstractBackgroundMatrix-assisted laser desorption ionisation (MALDI) mass spectrometry (MS) has been used for more than 30 years. Compared with other analytical techniques, it offers ease of use, high throughput, robustness, cost-effectiveness, rapid analysis and sensitivity. As advantages, current clinical techniques (e.g. immunoassays) are unable to directly measure the biomarker; rather, they measure secondary signals. MALDI-MS has been extensively researched for clinical applications, and it is set for a breakthrough as a routine tool for clinical diagnostics.ContentThis review reports on the principles of MALDI-MS and discusses current clinical applications and the future clinical prospects for MALDI-MS. Furthermore, the review assesses the limitations currently experienced in clinical assays, the advantages and the impact of MALDI-MS to transform clinical laboratories.SummaryMALDI-MS is widely used in clinical microbiology for the screening of microbial isolates; however, there is scope to apply MALDI-MS in the diagnosis, prognosis, therapeutic drug monitoring and biopsy imaging in many diseases.OutlookThere is considerable potential for MALDI-MS in clinic as a tool for screening, profiling and imaging because of its high sensitivity and specificity over alternative techniques.


2003 ◽  
Vol 58 (3-4) ◽  
pp. 177-180 ◽  
Author(s):  
Pınar Akbay ◽  
İhsan Çalιş ◽  
Jörg Heilmann ◽  
Otto Sticher

From the aerial parts of Ajuga salicifolia (L.) Schreber, a new ionone glycoside (3β-hydroxy- 7,8-dihydro-4-oxo-β-ionol-9-O-β-ᴅ-glucopyranoside) was isolated, along with the known compounds, corchoionoside C, 8-O-acetylmioporoside, ajugol, harpagide, 8-O-acetylharpagide, lavandulifolioside and leonosides A and B. This is the first report of the occurrence of ionone glycosides and 8-O-acetylmioporoside in Ajuga species. Ajugol, lavandulifolioside, leonoside A and B were isolated for the first time from Ajuga salicifolia. The structures were elucidated by means of 1D-, 2D-NMR spectroscopy, and HR-MALDI mass spectrometry.


RSC Advances ◽  
2015 ◽  
Vol 5 (19) ◽  
pp. 14090-14094 ◽  
Author(s):  
Judy Gopal ◽  
Hui-Fen Wu

MALDI-MS detection of bacteria in dental infection.


The Analyst ◽  
2017 ◽  
Vol 142 (14) ◽  
pp. 2518-2546 ◽  
Author(s):  
S. Francese ◽  
R. Bradshaw ◽  
N. Denison

Expanded range of retrievable intelligence from fingermarksviaMALDI MS based methods and increased operational capabilities of the technology.


2018 ◽  
Author(s):  
Shazia Khan ◽  
Diego F Cobice ◽  
Dawn EW Livingstone ◽  
C Logan Mackay ◽  
Scott P Webster ◽  
...  

2018 ◽  
Author(s):  
Asel Sartbaeva ◽  
Paul R. Raithby ◽  
Remi Castaing ◽  
Antony Nearchou

Through a combination of thermogravimetry, mass spectrometry and differential thermal analysis, we demonstrate for the first time that all four zeolites show experimental differences in their host-guest interactions with 18C6. In addition, we have estimated the kinetics of 18C6 decomposition, which is a technique that has not been applied to zeolites previously. Using these findings as a toolkit, a more rational use of OSDAs can be utilised to prepare designer zeolites. Furthermore, the new methodologies presented herein can be applied to current zeolites, such as MFI-type zeolites used in the petrochemical industry.


2020 ◽  
Vol 75 (14) ◽  
pp. 1749-1757
Author(s):  
E. A. Anikeenko ◽  
E. N. Rakhmatullina ◽  
D. I. Falev ◽  
O. Yu. Khoroshev ◽  
N. V. Ul’yanovskii ◽  
...  

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