On water: catalyst-free chemoselective synthesis of highly functionalized tetrahydroquinazolines from 2-aminophenylacrylate

2015 ◽  
Vol 17 (3) ◽  
pp. 1434-1441 ◽  
Author(s):  
Rakesh K. Saunthwal ◽  
Monika Patel ◽  
Rakesh K. Tiwari ◽  
Keykavous Parang ◽  
Akhilesh K. Verma
Keyword(s):  
Free Atom ◽  
Catalyst Free ◽  
Environmental Friendly ◽  
Chemoselective Synthesis

A green and catalyst free atom-ecomonic straightforward tandem approach for the synthesis of highly functionalized tetrahydroquinazolines by the reaction of 2-aminophenylacrylate 1 with isothiocyanates 2 using water as an environmental friendly solvent is described.

Chemoselective Synthesis of Aryl Ketones from Amides and Grignard Reagents via C(O)–N Bond Cleavage under Catalyst-Free Conditions

2019 ◽  
Vol 84 (18) ◽  
pp. 11823-11838 ◽  
Author(s):  
Popuri Sureshbabu ◽  
Sadaf Azeez ◽  
Nalluchamy Muniyappan ◽  
Shahulhameed Sabiah ◽  
Jeyakumar Kandasamy
Keyword(s):  
Bond Cleavage ◽  
Grignard Reagents ◽  
Catalyst Free ◽  
Chemoselective Synthesis ◽  
Aryl Ketones

A Catalyst‐Free Domino Protocol for the Chemoselective Synthesis of Multifunctionalised Pyrroles in Aqueous MediaviaNitroketene‐N,S‐Acetal Chemistry

2018 ◽  
Vol 3 (23) ◽  
pp. 6334-6337 ◽  
Author(s):  
Ankita Chaudhary ◽  
Jitender M. Khurana ◽  
Garima Khanna ◽  
Mohit Saroha
Keyword(s):  
Catalyst Free ◽  
Chemoselective Synthesis

scholarly journals Catalyst-Free Cascade Synthesis of Densely Functionalized Chromenes in Water

2019 ◽  
Vol 31 (11) ◽  
pp. 2532-2536
Author(s):  
Subrahmanya Ishwar Bhat
Keyword(s):  
Intramolecular Cyclization ◽  
Room Temperature ◽  
Product Yield ◽  
Catalyst Free ◽  
Environmental Friendly ◽  
Simple Filtration ◽  
High Product Yield ◽  
Filtration Technique

An expeditious and environmental friendly, general protocol has been developed for the synthesis of 2-amino-3-cyano-4H-chromenes via cascade Knoevenagel-Michael-intramolecular cyclization in water. Pure solid products were obtained by simple filtration technique. The aqueous catalyst-free reactions lead to high product yield at room temperature.

Convenient and efficient synthesis of disubstituted piperazine derivatives by catalyst-free, atom-economical and tricomponent domino reactions

RSC Advances ◽  
2015 ◽  
Vol 5 (14) ◽  
pp. 10768-10772 ◽  
Author(s):  
Hong-Ru Dong ◽  
Zi-Bao Chen ◽  
Rong-Shan Li ◽  
Heng-Shan Dong ◽  
Zhi-Xiang Xie
Keyword(s):  
Free Atom ◽  
Domino Reactions ◽  
Efficient Synthesis ◽  
One Pot ◽  
Diversity Oriented Synthesis ◽  
Mild Conditions ◽  
Catalyst Free ◽  
Piperazine Derivatives ◽  
High Yields

One-pot, atom-economical, catalyst-free and tri-component domino reactions are applied to diversity-oriented synthesis (DOS) of disubstituted piperazine derivatives under mild conditions with moderate to high yields.

A rapid, sustainable and environmental friendly protocol for the catalyst-free synthesis of 2-methyl-5-oxo-hexahydroquinoline-3-carboxylate via ultrasonic irradiation

2020 ◽  
Vol 28 ◽  
pp. 100432 ◽  
Author(s):  
Lagudu Devi ◽  
Alice R. Robert ◽  
Himavathi Ganja ◽  
Suresh Maddila ◽  
Sreekantha B. Jonnalagadda
Keyword(s):  
Ultrasonic Irradiation ◽  
Catalyst Free ◽  
Environmental Friendly

ChemInform Abstract: On Water: Catalyst-Free Chemoselective Synthesis of Highly Functionalized Tetrahydroquinazolines from 2-Aminophenylacrylate

ChemInform ◽  
2015 ◽  
Vol 46 (29) ◽  
pp. no-no
Author(s):  
Rakesh K. Saunthwal ◽  
Monika Patel ◽  
Rakesh K. Tiwari ◽  
Keykavous Parang ◽  
Akhilesh K. Verma
Keyword(s):  
Catalyst Free ◽  
Chemoselective Synthesis

Catalyst-Free Chemoselective Synthesis of 3,4-Dihydroquinazoline-2-thiones and 2-Imino[1,3]benzothiazines

2016 ◽  
Vol 81 (21) ◽  
pp. 10499-10505 ◽  
Author(s):  
Ting Xie ◽  
Yu Xiao ◽  
Shuai Zhao ◽  
Xiu-Qin Hu ◽  
Peng-Fei Xu
Keyword(s):  
Catalyst Free ◽  
Chemoselective Synthesis
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