scholarly journals Bitter taste genetics – the relationship to tasting, liking, consumption and health

2014 ◽  
Vol 5 (12) ◽  
pp. 3040-3054 ◽  
Author(s):  
Emma L. Beckett ◽  
Charlotte Martin ◽  
Zoe Yates ◽  
Martin Veysey ◽  
Konsta Duesing ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Health And Disease ◽  
Taste Genetics ◽  
Complex Relationships ◽  
The Relationship

Bitter is the most complex, and arguably the most important of human tastes; however the complex relationships to health and disease are yet to be fully elucidated.

Mast Cells as a Double-Edged Sword in Immunity: Their Function in Health and Disease. First of Two Parts

2020 ◽  
Vol 20 (5) ◽  
pp. 654-669
Author(s):  
Thea Magrone ◽  
Manrico Magrone ◽  
Emilio Jirillo
Keyword(s):  
Steady State ◽  
Mast Cells ◽  
Immune Cells ◽  
Food Antigens ◽  
Health And Disease ◽  
The Relationship

Mast cells (MCs) have recently been re-interpreted in the context of the immune scenario in the sense that their pro-allergic role is no longer exclusive. In fact, MCs even in steady state conditions maintain homeostatic functions, producing mediators and intensively cross-talking with other immune cells. Here, emphasis will be placed on the array of receptors expressed by MCs and the variety of cytokines they produce. Then, the bulk of data discussed will provide readers with a wealth of information on the dual ability of MCs not only to defend but also to offend the host. This double attitude of MCs relies on many variables, such as their subsets, tissues of residency and type of stimuli ranging from microbes to allergens and food antigens. Finally, the relationship between MCs with basophils and eosinophils will be discussed.

scholarly journals Circadian Blood Pressure Rhythm in Cardiovascular and Renal Health and Disease

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 868
Author(s):  
Jiayang Zhang ◽  
Ruoyu Sun ◽  
Tingting Jiang ◽  
Guangrui Yang ◽  
Lihong Chen
Keyword(s):  
Blood Pressure ◽  
Circadian Rhythm ◽  
Molecular Mechanisms ◽  
Current Understanding ◽  
Renal Outcomes ◽  
Circadian Blood Pressure ◽  
Health And Disease ◽  
The Relationship

Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported to be associated with worsened cardiovascular and renal outcomes, however the underlying molecular mechanisms are still not clear. In this review, we briefly summarized the current understanding of the circadian BP regulation and provided therapeutic overview of the relationship between circadian BP rhythm and cardiovascular and renal health and disease.

Open questions in sweet, umami and bitter taste genetics

2021 ◽  
Vol 20 ◽  
pp. 174-179
Author(s):  
Davide Risso ◽  
Dennis Drayna ◽  
Sergio Tofanelli ◽  
Gabriella Morini
Keyword(s):  
Bitter Taste ◽  
Open Questions ◽  
Taste Genetics

scholarly journals A potential sex dimorphism in the relationship between bitter taste and alcohol consumption

2017 ◽  
Vol 8 (3) ◽  
pp. 1116-1123 ◽  
Author(s):  
Emma Louise Beckett ◽  
Konsta Duesing ◽  
Lyndell Boyd ◽  
Zoe Yates ◽  
Martin Veysey ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Intake ◽  
Bitter Taste ◽  
Disease Risk ◽  
Specific Interactions ◽  
Sex Dimorphism ◽  
Taste Phenotype ◽  
The Relationship

Sex-specific interactions between bitter taste phenotype, TAS2R38 genotype and alcohol intake may explain variance is previous studies, and may have implications for disease risk.

What is Philosophy of Medicine?

PARADIGMI ◽  
2011 ◽  
pp. 11-28
Author(s):  
Elselijn Kingma
Keyword(s):  
Philosophy Of Medicine ◽  
Medical Knowledge ◽  
Concepts Of Health ◽  
Health And Disease ◽  
The Relationship

Philosophy of Medicine is considered a new and emerging discipline. This paper presents an overview of philosophy of medicine, discusses its relation to bioethics and to other areas of philosophy, and introduces three potential topics for research in the philosophy of medicine: concepts of health and disease, the relationship between medicine and psychiatry, and the problems of medical knowledge and evidence.

scholarly journals The genetic factors involved in functional food efficacy on cardiovascular disease etiology

SURG Journal ◽  
2019 ◽  
Vol 11 ◽  
Author(s):  
Maarij Siddiqi
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Nutritional Value ◽  
Functional Foods ◽  
Genetic Factors ◽  
Dietary Guidelines ◽  
Disease Etiology ◽  
Modifiable Factor ◽  
Health And Disease ◽  
The Relationship

While the impacts of modifiable and non-modifiable risk factors on chronic diseases such as cardiovascular disease (CVD) are widely established, the interactions between such coexisting risk factors and their subsequent effects on the promotion or suppression of CVD are less known. As part of the diet, functional foods are considered a modifiable factor that influence health beyond their basic nutritional value. The relationship between these functional foods and the underlying genome, along with their joint implication in health and disease, forms the focus of the emerging field of nutrigenomics. Reviewed in this paper are some prominent gene-diet interactions demonstrated in CVD etiology. Specifically, the interaction between foods such as phytosterols and isoflavones with genetic factors of the consuming population are examined in relation to CVD. By determining how nutritional intake affects genetics and vice versa, we create the potential to offer improved dietary guidelines to certain individuals, subgroups, or populations in order to maximize health benefits of specific diets.

Pulmonary Function Testing

2017 ◽  
Author(s):  
Maryl Kreider
Keyword(s):  
Pulmonary Function ◽  
Forced Expiratory Volume ◽  
Pulmonary Function Testing ◽  
Flow Volume ◽  
Functional Impairments ◽  
Clinical Scenarios ◽  
Maximum Expiratory Flow ◽  
Health And Disease ◽  
The Relationship ◽  
Function Testing

Intelligent management of pulmonary disease requires a fundamental understanding of the complex interrelationships between multiple elements that interact to maintain homeostasis in the respiratory system. This chapter discusses the physiologic basis for pulmonary function testing and the use of these tests to diagnose disease, quantitate functional impairments, and follow the effects of treatment. Figures illustrate the relationships between lung volume, airway conductance, and airway resistance; the relationship between forced expiratory volume and time (spirogram); the relationship between spirometry and maximum expiratory flow volume; dynamic airway compression; patterns of abnormalities seen on flow-volume curves; lung volumes and capacities; pressure-volume relationships in health and disease; and the clinical assessment of lung function. Tables list the capacities and volumes of gas contained in the lungs during various breathing maneuvers, conditions associated with alterations in diffusing capacity, and recommendations for tests for various clinical scenarios. This review contains 7 highly rendered figures, 3 tables, and 86 references.

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