Droplet based microfluidics: spectroscopic characterization of levofloxacin and its SERS detection

2015 ◽  
Vol 17 (33) ◽  
pp. 21236-21242 ◽  
Author(s):  
I. J. Hidi ◽  
M. Jahn ◽  
K. Weber ◽  
D. Cialla-May ◽  
J. Popp
Keyword(s):  
Aqueous Solution ◽  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Spectroscopic Characterization ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection

The determination of the absorption behavior of levofloxacin (levaquin) on the surface of silver nanoparticles and its determination in aqueous solution by droplet based microfluidics combined with surface enhanced Raman spectroscopy.

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

scholarly journals Detection of a Sudan dye at low concentrations by surface-enhanced Raman spectroscopy using silver nanoparticles

2019 ◽  
Vol 29 (4) ◽  
pp. 521
Author(s):  
Tran Cao Dao ◽  
Truc Quynh Ngan Luong ◽  
Tuan Anh Cao ◽  
Ngoc Minh Kieu
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Good Method ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Sudan Dyes ◽  
Sudan I ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection

Sudan dyes are red colorants banned from use for food due to their toxic properties. However, because of the cheapness, they are sometimes adulterated into food illegally. Currently surface-enhanced Raman spectroscopy (SERS) is emerging as a good method to detect residues (including trace amounts) of Sudan dyes in food. In this report we present the SERS detection of Sudan I (a type of Sudan dyes) to concentrations as low as 1 ppb, using a very simple SERS substrate, which is made from silver nanoparticles chemically deposited on silicon surface.

Application of silver nanoparticles decorated with β-cyclodextrin in determination of 6-mercaptopurine by surface-enhanced Raman spectroscopy

2015 ◽  
Vol 7 (16) ◽  
pp. 6520-6527 ◽  
Author(s):  
Lei Yang ◽  
Yanhua Chen ◽  
Hongli Li ◽  
Lan Luo ◽  
Ying Zhao ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Surface Enhanced Raman Spectroscopy ◽  
Selective Method ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Sers Active Substrate

A highly sensitive and selective method using silver nanoparticles decorated with β-cyclodextrin as a SERS-active substrate was developed for detecting 6-mercaptopurine.

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