scholarly journals A survey of advancements in nucleic acid-based logic gates and computing for applications in biotechnology and biomedicine

2015 ◽  
Vol 51 (18) ◽  
pp. 3723-3734 ◽  
Author(s):  
Cuichen Wu ◽  
Shuo Wan ◽  
Weijia Hou ◽  
Liqin Zhang ◽  
Jiehua Xu ◽  
...  

Nucleic acid based logic systems have been rationally designed and functionalized to better serve bioanalytical and biomedical applications.

2021 ◽  
Vol 12 (15) ◽  
pp. 5473-5483
Author(s):  
Zhixin Zhou ◽  
Jianbang Wang ◽  
R. D. Levine ◽  
Francoise Remacle ◽  
Itamar Willner

A nucleic acid-based constitutional dynamic network (CDN) provides a single functional computational module for diverse input-guided logic operations and computing circuits.


Aggregate ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 133-144
Author(s):  
Run Tian ◽  
Zhaoran Wang ◽  
Jianbing Liu ◽  
Qiao Jiang ◽  
Baoquan Ding

2015 ◽  
Vol 43 (4) ◽  
pp. 277-296 ◽  
Author(s):  
Xenia Meshik ◽  
Sidra Farid ◽  
Min Choi ◽  
Yi Lan ◽  
Souvik Mukherjee ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16479-16491 ◽  
Author(s):  
Zhiguang Suo ◽  
Jingqi Chen ◽  
Xialing Hou ◽  
Ziheng Hu ◽  
Feifei Xing ◽  
...  

Recent progress in DNA-based nanomaterials is summarized, ranging from applications in biosensors, biomedicine/imaging, and molecular logic gates to emerging nanomachines, as well as future perspective discussions.


2018 ◽  
Vol 19 (9) ◽  
pp. 3861-3873 ◽  
Author(s):  
Amy C. Kauffman ◽  
Alexandra S. Piotrowski-Daspit ◽  
Kay H. Nakazawa ◽  
Yuhang Jiang ◽  
Amit Datye ◽  
...  

Nanomedicine ◽  
2007 ◽  
Vol 2 (6) ◽  
pp. 817-830 ◽  
Author(s):  
Friedrich C Simmel

Nanoscale ◽  
2015 ◽  
Vol 7 (18) ◽  
pp. 8289-8293 ◽  
Author(s):  
Rijun Gui ◽  
Hui Jin ◽  
Zonghua Wang ◽  
Feifei Zhang ◽  
Jianfei Xia ◽  
...  

2016 ◽  
Vol 52 (1) ◽  
pp. 179-182 ◽  
Author(s):  
Lijun Xu ◽  
Shanni Hong ◽  
Na Sun ◽  
Kewei Wang ◽  
Lu Zhou ◽  
...  

Berberine is reported as a light-up fluorescence ligand for i-motif structures, which enables the development of label-free DNA-based logic gates.


2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Seth G. Abels ◽  
Emil F. Khisamutdinov

AbstractMolecular computers have existed on our planet for more than 3.5 billion years. Molecular computing devices, composed of biological substances such as nucleic acids, are responsible for the logical processing of a variety of inputs, creating viable outputs that are key components of the cellular machinery of all living organisms. We have begun to adopt some of the structural and functional knowledge of the cellular apparatus in order to fabricate nucleic-acid-based molecular computers in vitro and in vivo. Nucleic acid computing is directly dependent on advances in DNA and RNA nanotechnology. The field is still emerging and a number of challenges persist. Perhaps the most salient among these is how to translate a variety of nucleic-acid-based logic gates, developed by numerous research laboratories, into the realm of silicon-based computing. This mini-review provides some basic information on the advances in nucleic-acid-based computing and its potential to serve as an alternative that can revolutionize silicon-based technology.


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