scholarly journals Nucleic acid–based aggregates and their biomedical applications

Aggregate ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 133-144
Author(s):  
Run Tian ◽  
Zhaoran Wang ◽  
Jianbing Liu ◽  
Qiao Jiang ◽  
Baoquan Ding
Keyword(s):  
Nucleic Acid ◽  
Biomedical Applications

Biomedical Applications of Quantum Dots, Nucleic Acid-Based Aptamers, and Nanostructures in Biosensors

2015 ◽  
Vol 43 (4) ◽  
pp. 277-296 ◽  
Author(s):  
Xenia Meshik ◽  
Sidra Farid ◽  
Min Choi ◽  
Yi Lan ◽  
Souvik Mukherjee ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Nucleic Acid ◽  
Biomedical Applications

scholarly journals Tunability of Biodegradable Poly(amine-co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications

2018 ◽  
Vol 19 (9) ◽  
pp. 3861-3873 ◽  
Author(s):  
Amy C. Kauffman ◽  
Alexandra S. Piotrowski-Daspit ◽  
Kay H. Nakazawa ◽  
Yuhang Jiang ◽  
Amit Datye ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Biomedical Applications ◽  
Nucleic Acid Delivery ◽  
Biodegradable Poly

scholarly journals A survey of advancements in nucleic acid-based logic gates and computing for applications in biotechnology and biomedicine

2015 ◽  
Vol 51 (18) ◽  
pp. 3723-3734 ◽  
Author(s):  
Cuichen Wu ◽  
Shuo Wan ◽  
Weijia Hou ◽  
Liqin Zhang ◽  
Jiehua Xu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Biomedical Applications ◽  
Logic Gates ◽  
Logic Systems

Nucleic acid based logic systems have been rationally designed and functionalized to better serve bioanalytical and biomedical applications.

Towards biomedical applications for nucleic acid nanodevices

Nanomedicine ◽  
2007 ◽  
Vol 2 (6) ◽  
pp. 817-830 ◽  
Author(s):  
Friedrich C Simmel
Keyword(s):  
Nucleic Acid ◽  
Biomedical Applications

scholarly journals Nucleic acid-based nanoengineering: novel structures for biomedical applications

2011 ◽  
Vol 1 (5) ◽  
pp. 702-724 ◽  
Author(s):  
Hanying Li ◽  
Thomas H. LaBean ◽  
Kam W. Leong
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Single Molecule ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Base Pairs ◽  
Single Molecule Level ◽  
Stimulus Responsive ◽  
Bioactive Agents ◽  
Novel Structures

Nanoengineering exploits the interactions of materials at the nanometre scale to create functional nanostructures. It relies on the precise organization of nanomaterials to achieve unique functionality. There are no interactions more elegant than those governing nucleic acids via Watson–Crick base-pairing rules. The infinite combinations of DNA/RNA base pairs and their remarkable molecular recognition capability can give rise to interesting nanostructures that are only limited by our imagination. Over the past years, creative assembly of nucleic acids has fashioned a plethora of two-dimensional and three-dimensional nanostructures with precisely controlled size, shape and spatial functionalization. These nanostructures have been precisely patterned with molecules, proteins and gold nanoparticles for the observation of chemical reactions at the single molecule level, activation of enzymatic cascade and novel modality of photonic detection, respectively. Recently, they have also been engineered to encapsulate and release bioactive agents in a stimulus-responsive manner for therapeutic applications. The future of nucleic acid-based nanoengineering is bright and exciting. In this review, we will discuss the strategies to control the assembly of nucleic acids and highlight the recent efforts to build functional nucleic acid nanodevices for nanomedicine.

scholarly journals Biotechnological and Biomedical Applications of Enzymes Involved in the Synthesis of Nucleosides and Nucleotides

Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1147
Author(s):  
Jesús Fernández-Lucas
Keyword(s):  
Nucleic Acid ◽  
Cell Growth ◽  
Dna Synthesis ◽  
Biomedical Applications ◽  
Building Blocks ◽  
Rna And Dna Synthesis ◽  
Rna And Dna

Nucleic acid derivatives are involved in cell growth and replication, but they are also particularly important as building blocks for RNA and DNA synthesis [...]

Expanding the Chemical Diversity of DNA

Synlett ◽  
2018 ◽  
Vol 29 (11) ◽  
pp. 1405-1414 ◽  
Author(s):  
Ryan Hili ◽  
Chun Guo ◽  
Dehui Kong ◽  
Yi Lei
Keyword(s):  
Nucleic Acid ◽  
Molecular Recognition ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Molecular Target ◽  
Chemical Diversity ◽  
Specific Reaction ◽  
Chemical Complexity ◽  
Current State ◽  
The Rich

Nucleic acid polymers can be evolved to exhibit desired properties, including molecular recognition of a molecular target and catalysis of a specific reaction. These properties can be readily evolved despite the dearth of chemical diversity available to nucleic acid polymers, especially when compared to the rich chemical complexity of proteins. Expansion of nucleic acid chemical diversity has therefore been an important thrust for improving their properties for analytical and biomedical applications. Herein, we briefly describe the current state-of-the-art for the sequence-defined incorporation of modifications throughout an evolvable nucleic acid polymer. This includes contributions from our own lab, which have expanded the chemical diversity of nucleic acid polymers closer to the level observed in proteinogenic polymers.1 Introduction2 Polymerase-Catalyzed Synthesis of Modified Nucleic Acid ­Polymers3 Ligase-Catalyzed Oligonucleotide Polymerization (LOOPER)4 LOOPER with Small Modifications5 LOOPER with Large Modifications6 Evolution of Aptamers Derived from LOOPER Libraries7 Outlook

scholarly journals Nucleic acid-templated functional nanocomposites for biomedical applications

2017 ◽  
Vol 20 (4) ◽  
pp. 179-190 ◽  
Author(s):  
Li Zhou ◽  
Jinsong Ren ◽  
Xiaogang Qu
Keyword(s):  
Nucleic Acid ◽  
Biomedical Applications
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