A Lewis acid activated reaction of Zn with EtI to promote highly enantioselective alkyne additions to aldehydes

2015 ◽  
Vol 51 (2) ◽  
pp. 358-361 ◽  
Author(s):  
Shan-yong Chen ◽  
Winnie Liu ◽  
Xuedan Wu ◽  
Jun Ying ◽  
Xiaoqi Yu ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Alkyne Addition

Zn powder and EtI in the presence of (S)-BINOL and Ti(OiPr)4 promote highly enantioselective alkyne addition to aldehydes at rt to generate chiral propargylic alcohols.

Lewis Acid-Catalyzed Rearrangement of Fluoroalkylated Propargylic Alcohols: An Alternative Approach to β-Fluoroalkyl-α,β-enones

Synlett ◽  
2019 ◽  
Vol 30 (03) ◽  
pp. 356-360 ◽  
Author(s):  
Manickavasakam Ramasamy ◽  
Hui-Chang Lin ◽  
Sheng-Chu Kuo ◽  
Min-Tsang Hsieh
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Alternative Approach ◽  
Acid Catalyzed ◽  
High Yields ◽  
High Stereoselectivity

A practical Lewis acid-catalyzed Meyer–Schuster rearrangement of fluoroalkylated propargylic alcohols, leading to a series of β-fluoroalkyl-α,β-enones, is developed. The methodology reported herein features moderate to high yields and high stereoselectivity in the synthesis of β-alkyl-β-fluoroalkyl-α,β-enones.

Lewis Acid Catalyzed Cyclization of Propargylic Alcohols with 2-Vinylphenol

2016 ◽  
Vol 18 (15) ◽  
pp. 3866-3869 ◽  
Author(s):  
Ya-Ping Han ◽  
Xian-Rong Song ◽  
Yi-Feng Qiu ◽  
Xue-Song Li ◽  
Heng-Rui Zhang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Acid Catalyzed

ChemInform Abstract: Lewis Acid Catalyzed Cyclization of Propargylic Alcohols with 2-Vinylphenol.

ChemInform ◽  
2016 ◽  
Vol 47 (52) ◽  
Author(s):  
Ya-Ping Han ◽  
Xian-Rong Song ◽  
Yi-Feng Qiu ◽  
Xue-Song Li ◽  
Heng-Rui Zhang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Acid Catalyzed

Lewis Acid Mediated Tandem Reaction of Propargylic Alcohols to Tetrazoles Involving CO- and CC-Bond Cleavage Reactions and a CN-Bond Formation

2014 ◽  
Vol 20 (38) ◽  
pp. 12046-12050 ◽  
Author(s):  
Xian-Rong Song ◽  
Ya-Ping Han ◽  
Yi-Feng Qiu ◽  
Zi-Hang Qiu ◽  
Xue-Yuan Liu ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Tandem Reaction ◽  
Propargylic Alcohols ◽  
Cleavage Reactions

Lewis Acid Mediated Tandem Reaction of Propargylic Alcohols with Hydroxylamine Hydrochloride To Give α,β-Unsaturated Amides and Alkenyl Nitriles

2015 ◽  
Vol 80 (18) ◽  
pp. 9200-9207 ◽  
Author(s):  
Ya-Ping Han ◽  
Xian-Rong Song ◽  
Yi-Feng Qiu ◽  
Xin-Hua Hao ◽  
Jia Wang ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Hydroxylamine Hydrochloride ◽  
Tandem Reaction ◽  
Propargylic Alcohols

scholarly journals Corrigendum: Lewis Acid-Catalyzed Formal [3+3] Annulation of Propargylic Alcohols with 4-Hydroxy-2H -chromen-2-ones

2018 ◽  
Vol 360 (16) ◽  
pp. 3181-3181
Author(s):  
Ya-Ping Han ◽  
Xue-Song Li ◽  
Ming Li ◽  
Xin-Yu Zhu ◽  
Yong-Min Liang
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Acid Catalyzed

ChemInform Abstract: Lewis Acid Promoted Three-Component Reactions of Propargylic Alcohols with 2-Butynedioates and Secondary Amines.

ChemInform ◽  
2012 ◽  
Vol 43 (10) ◽  
pp. no-no
Author(s):  
Guangwei Yin ◽  
Yuanxun Zhu ◽  
Ping Lu ◽  
Yanguang Wang
Keyword(s):  
Lewis Acid ◽  
Secondary Amines ◽  
Propargylic Alcohols

ChemInform Abstract: Development of Zn-ProPhenol-Catalyzed Asymmetric Alkyne Addition: Synthesis of Chiral Propargylic Alcohols.

ChemInform ◽  
2013 ◽  
Vol 44 (20) ◽  
pp. no-no
Author(s):  
Barry M. Trost ◽  
Mark J. Bartlett ◽  
Andrew H. Weiss ◽  
Axel Jacobi von Wangelin ◽  
Vincent S. Chan
Keyword(s):  
Propargylic Alcohols ◽  
Alkyne Addition

scholarly journals Lewis Acid-Catalyzed Formal [3+3] Annulation of Propargylic Alcohols with 4-Hydroxy-2H -chromen-2-ones

2018 ◽  
Vol 360 (15) ◽  
pp. 2796-2800 ◽  
Author(s):  
Ya-Ping Han ◽  
Xue-Song Li ◽  
Ming Li ◽  
Xin-Yu Zhu ◽  
Yong-Min Liang
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Acid Catalyzed

Synthesis of 1 H ‐Pyrrolo[1,2‐ a ]indoles via Lewis Acid‐Catalyzed Annulation of Propargylic Alcohols with 2‐Ethynylanilines

2020 ◽  
Vol 362 (6) ◽  
pp. 1399-1404 ◽  
Author(s):  
Li‐Juan Du ◽  
Ya‐Ping Han ◽  
Hong‐Yu Zhang ◽  
Yuecheng Zhang ◽  
Jiquan Zhao ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Propargylic Alcohols ◽  
Acid Catalyzed
Sign in / Sign up

Export Citation Format

Share Document