One-pot synthesis of dibenzo[b,h][1,6]naphthyridines from 2-acetylaminobenzaldehyde: application to a fluorescent DNA-binding compound

2014 ◽  
Vol 50 (98) ◽  
pp. 15525-15528 ◽  
Author(s):  
Kentaro Okuma ◽  
Tomohiro Koga ◽  
Saori Ozaki ◽  
Yutaro Suzuki ◽  
Kenta Horigami ◽  
...  
Keyword(s):  
Dna Binding ◽  
Methyl Ketones ◽  
Strong Fluorescence ◽  
One Pot ◽  
One Pot Synthesis

Dibenzo[b,h][1,6]naphthyridines were synthesized in one pot by reacting 2-acetylamainobnezaldehyde with methyl ketones under basic conditions, methylation of which showed strong fluorescence.

Facile Approach to Geminal Heterodihalogenation. One-Pot Synthesis of α-Bromo-α-Chloro Ketones

Synlett ◽  
2020 ◽  
Vol 31 (14) ◽  
pp. 1430-1434
Author(s):  
Ming Bian ◽  
Jin-feng Zhou ◽  
Dong-min Tang
Keyword(s):  
Drug Discovery ◽  
Dimethyl Sulfoxide ◽  
Functional Groups ◽  
Methyl Ketones ◽  
One Pot ◽  
One Pot Synthesis ◽  
Operational Simplicity

An efficient and practical protocol for the geminal heterodihalogenation of methyl ketones by using readily available dimethyl sulfoxide and a combination of HCl and HBr is reported. Control experiments suggested that the acidity of the solution, as well as the oxidizing ability and nucleophilicity of the dimethyl sulfoxide might work cooperatively in ensuring the success of the tandem substitution. Its operational simplicity, easy accessibility, and mild oxidative conditions suggest that the present strategy might be useful for the assembly of bromochloromethyl functional groups in drug discovery.

One-Pot Synthesis of Pyrimido[4,5-d]pyrimidine Derivatives and Investigation of Their Antibacterial, Antioxidant, DNA-Binding and Voltammetric Characteristics

2019 ◽  
Vol 4 (3) ◽  
pp. 990-996
Author(s):  
Rangappa Santosh ◽  
Priyodip Paul ◽  
Mukunthan K. Selvam ◽  
Chenthattil Raril ◽  
Panchangam M. Krishna ◽  
...  
Keyword(s):  
Dna Binding ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
Voltammetric Characteristics

Polyethylene glycol-bonded triethylammonium l-prolinate: a new biodegradable amino-acid-based ionic liquid for the one-pot synthesis of bis(pyrazolyl)methanes as DNA binding agents

2020 ◽  
Vol 44 (39) ◽  
pp. 16995-17012
Author(s):  
Reza Kordnezhadian ◽  
Mohsen Shekouhy ◽  
Somaye Karimian ◽  
Zohreh Tavaf ◽  
Saeed Malek-Hosseini ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Polyethylene Glycol ◽  
Amino Acid ◽  
Dna Binding ◽  
One Pot ◽  
One Pot Synthesis ◽  
Binding Agents ◽  
Dna Binding Agents ◽  
The One

[PEG-TEA]LP, as a new biodegradable ionic liquid catalyst, was successfully synthesized, characterized, and applied to the one-pot pseudo-five-component synthesis of bis(pyrazolyl)methanes.

Difluorohomologization-Halogenation of Methyl Ketones: One-Pot Synthesis of β-Halo-α,α-Difluoroketones

2018 ◽  
Vol 76 (12) ◽  
pp. 983 ◽  
Author(s):  
Xiaoning Song ◽  
Shan Yang ◽  
Xin Wang ◽  
Mang Wang
Keyword(s):  
Methyl Ketones ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis, characterization, DNA binding and enzymatic studies of 4-methyl trans-cinnamate zinc(II)-mixed ligand complexes

2015 ◽  
Vol 68 (20) ◽  
pp. 3636-3650 ◽  
Author(s):  
Syeda Tahira Hafeez ◽  
Muhammad Nawaz Tahir ◽  
Saqib Ali ◽  
Muhammad Iqbal ◽  
Hussain Gulab ◽  
...  
Keyword(s):  
Dna Binding ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
One Pot ◽  
One Pot Synthesis

2-Thieno/Selenopyrano[2,3-b]quinolines: Microwave-Induced One-Pot Synthesis, DNA Binding, and Photocleavage Studies

2009 ◽  
Vol 184 (10) ◽  
pp. 2583-2593 ◽  
Author(s):  
H. R. Prakash Naik ◽  
H. S. Bhojya Naik ◽  
T. R. Ravikumar Naik ◽  
T. Aravinda ◽  
D. S. Lamani ◽  
...  
Keyword(s):  
Dna Binding ◽  
One Pot ◽  
One Pot Synthesis
Sign in / Sign up

Export Citation Format

Share Document