One-Pot Synthesis of Pyrimido[4,5-d]pyrimidine Derivatives and Investigation of Their Antibacterial, Antioxidant, DNA-Binding and Voltammetric Characteristics

2019 ◽  
Vol 4 (3) ◽  
pp. 990-996
Author(s):  
Rangappa Santosh ◽  
Priyodip Paul ◽  
Mukunthan K. Selvam ◽  
Chenthattil Raril ◽  
Panchangam M. Krishna ◽  
...  
Keyword(s):  
Dna Binding ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
Voltammetric Characteristics

Three-Component, One-Pot Synthesis of Pyrido[2,3-d]pyrimidine Derivatives Catalyzed by KF-Alumina.

ChemInform ◽  
2005 ◽  
Vol 36 (49) ◽  
Author(s):  
Xiang-Shan Wang ◽  
Zhao-Sen Zeng ◽  
Da-Qing Shi ◽  
Shu-Jiang Tu ◽  
Xian-Yong Wei ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals A Synthesis of 4-Chloro-2-(trichloromethyl)pyrimidines and Their Study in Nucleophilic Substitution

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 530-537 ◽  
Author(s):  
Moisés Romero-Ortega ◽  
Michelle Trujillo-Lagunas ◽  
Ignacio Medina-Mercado ◽  
Ivann Zaragoza-Galicia ◽  
Horacio Olivo
Keyword(s):  
Nucleophilic Substitution ◽  
Intramolecular Cyclization ◽  
Nitrogen Heterocycles ◽  
Cyclization Reaction ◽  
Substitution Reactions ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Acyl Chlorides ◽  
Nucleophilic Substitution Reactions ◽  
One Pot Synthesis

A convenient two-step, one-pot synthesis of 4-chloro-2-(trichloromethyl)pyrimidines starting from 2-(trichloromethyl)-1,3-diazabutadienes is described. These nitrogen heterocycles were prepared by a sequential acylation/intramolecular cyclization reaction between 2-(trichloromethyl)-1,3-diazabutadienes and acyl chlorides in the presence of triethylamine followed by treatment with POCl3. This is the first report for the synthesis of this type of 4-chloro-2-(trichloromethyl)pyrimidine derivatives and serves as a source for a wide variety of other substituted pyrimidines by nucleophilic substitution reactions.

One-Pot Synthesis of Imidazo[1,5-c]pyrimidine Derivatives from a 4,6-Dichloropyrimidine Derivative and Benzyl Isocyanides

Heterocycles ◽  
2017 ◽  
Vol 94 (1) ◽  
pp. 140 ◽  
Author(s):  
Kazuhiro Kobayashi ◽  
Daiki Fujiwara ◽  
Yuuho Shigemura ◽  
Hidetaka Hiyoshi ◽  
Kazuto Umezu
Keyword(s):  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis

Light-induced one-pot synthesis of pyrimidine derivatives from vinyl azides

2020 ◽  
Vol 18 (26) ◽  
pp. 4971-4982 ◽  
Author(s):  
Tuan K. Nguyen ◽  
Gleb D. Titov ◽  
Olesya V. Khoroshilova ◽  
Mikhail A. Kinzhalov ◽  
Nikolai V. Rostovskii
Keyword(s):  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
Uv Led ◽  
Vinyl Azides

A one-pot synthesis of tetrasubstituted dihydropyrimidine and pyrimidine derivatives was developed on the basis of UV-LED photolysis of α-azidocinnamates as a key stage.

Polyethylene glycol-bonded triethylammonium l-prolinate: a new biodegradable amino-acid-based ionic liquid for the one-pot synthesis of bis(pyrazolyl)methanes as DNA binding agents

2020 ◽  
Vol 44 (39) ◽  
pp. 16995-17012
Author(s):  
Reza Kordnezhadian ◽  
Mohsen Shekouhy ◽  
Somaye Karimian ◽  
Zohreh Tavaf ◽  
Saeed Malek-Hosseini ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Polyethylene Glycol ◽  
Amino Acid ◽  
Dna Binding ◽  
One Pot ◽  
One Pot Synthesis ◽  
Binding Agents ◽  
Dna Binding Agents ◽  
The One

[PEG-TEA]LP, as a new biodegradable ionic liquid catalyst, was successfully synthesized, characterized, and applied to the one-pot pseudo-five-component synthesis of bis(pyrazolyl)methanes.

Promiscuous Zinc-Dependent Acylase-Mediated One-Pot Synthesis of Monosaccharide-Containing Pyrimidine Derivatives in Organic Medium

2009 ◽  
Vol 351 (11-12) ◽  
pp. 1833-1841 ◽  
Author(s):  
Qi Wu ◽  
Jian-Ming Xu ◽  
Li Xia ◽  
Jun-Liang Wang ◽  
Xian-Fu Lin
Keyword(s):  
Organic Medium ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis
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