Colorimetric detection of human chorionic gonadotropin using catalytic gold nanoparticles and a peptide aptamer

2014 ◽  
Vol 50 (92) ◽  
pp. 14443-14446 ◽  
Author(s):  
Chia-Chen Chang ◽  
Chie-Pein Chen ◽  
Chung-Han Lee ◽  
Chen-Yu Chen ◽  
Chii-Wann Lin
Keyword(s):  
Gold Nanoparticles ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Colorimetric Detection ◽  
Peptide Aptamer

Facile colorimetric detection of human chorionic gonadotropin based on the peptide-induced aggregation of gold nanoparticles

2015 ◽  
Vol 7 (1) ◽  
pp. 29-33 ◽  
Author(s):  
Chia-Chen Chang ◽  
Chen-Yu Chen ◽  
Chie-Pein Chen ◽  
Chii-Wann Lin
Keyword(s):  
Gold Nanoparticles ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Detection Method ◽  
Colorimetric Detection ◽  
Optical Detection ◽  
Binding Peptide ◽  
Induced Aggregation

A facile and rapid optical detection method of human chorionic gonadotropin (hCG) was developed by using the hCG-binding peptide and the anti-aggregation of gold nanoparticles (AuNPs).

A highly sensitive gold nanoparticle bioprobe based electrochemical immunosensor using screen printed graphene biochip

RSC Advances ◽  
2014 ◽  
Vol 4 (102) ◽  
pp. 58460-58466 ◽  
Author(s):  
Syazana Abdullah Lim ◽  
Hiroyuki Yoshikawa ◽  
Eiichi Tamiya ◽  
Hartini Mohd Yasin ◽  
Minhaz Uddin Ahmed
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Electrode Material ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Electrochemical Label ◽  
Screen Printed

This study describes a highly sensitive electrochemical immunosensor for the detection of human chorionic gonadotropin (hCG) that uses gold nanoparticles (AuNP) as the electrochemical label and graphene as electrode material.

A simple unlabeled human chorionic gonadotropin biosensor based on peptide aptamer

2021 ◽  
Author(s):  
Peng Yu ◽  
Huanhuan Li ◽  
Tongji Cai ◽  
Yi Ren ◽  
Jing Huang ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Colloidal Gold ◽  
Biochemical Indicator ◽  
Biochemical Analyzer ◽  
Peptide Aptamer

As an essential biochemical indicator in the field of pregnancy and oncology, human chorionic gonadotropin (HCG) can be evaluated by colloidal gold immunochromatographic paper and quantified by biochemical analyzer in...

scholarly journals Assessment of Disulfide-linked Gold Nanoparticles as Colorimetric Sensor for Human Chorionic Gonadotropin Detection

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Muhammad Anas Yuzairi Mohd Yusri ◽  
Mohd Hafiz Abu Hassan ◽  
Syaza Azhari
Keyword(s):  
Gold Nanoparticles ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Spectroscopic Characterization ◽  
Colorimetric Sensor ◽  
Glutathione Disulfide ◽  
Pre Treatment ◽  
Treatment Step ◽  
Sensing Performance

Gold nanoparticles (AuNPs) are a highly versatile compound to be used in sensing components due to their unique physicochemical and optical properties. Due to its flexibility for surface conjugation, glutathione disulfide-linked gold nanoparticle (AuNP-GSSG) was produced in this study to assess its sensing performance as a colorimetric sensor for human chorionic gonadotropin (HCG). Spectroscopic characterization of AuNP-GSSG confirmed the conjugation of GSSG onto the surface of AuNPs. AuNP-GSSG also showed high sensory performance with good linearity and low detection limit. However, due to the high percentage of interference, usage of AuNP-GSSG as an HCG sensor requires further pre-treatment step to reduce the interference and increase the sensor accuracy.

scholarly journals Review on Application of Gold Nanoparticles and Paper-based Microfluidic Analytical Device in Detection of Human Chorionic Gonadotropin

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Muhammad Anas Yuzairi Mohd Yusri ◽  
Mohd Hafiz Abu Hassan ◽  
Syaza Azhari
Keyword(s):  
Gold Nanoparticles ◽  
Physical Properties ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Point Of Care ◽  
Medical Diagnostics ◽  
Detection Methods ◽  
Point Of Care Testing ◽  
User Friendly ◽  
Analytical Device

Human chorionic gonadotropin (HCG) has been amongst of essential part of medical diagnostics in gynaecology and oncology since its discovery. Application of gold nanoparticles in detecting HCG is due to gold nanoparticles possess extraordinary optical and physical properties, making them invaluable in various prominent aspects, including its synthesis, stabilization, and functionalization as a sensor. In addition, microfluidic analytical device, a platform for point-of-care testing and numerous applications in various field, can be applied for detection of HCG using diverse types of detection methods. From the literatures, combination of gold nanoparticles and microfluidic analytical device can be assembled to obtain a rapid, simple and user-friendly analytical site for detection of HCG.

Sign in / Sign up

Export Citation Format

Share Document