One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin

2014 ◽  
Vol 50 (86) ◽  
pp. 13103-13106 ◽  
Author(s):  
Cheng Zheng ◽  
Ai-Xian Zheng ◽  
Bo Liu ◽  
Xiao-Long Zhang ◽  
Yu He ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Colorimetric Detection ◽  
Protein Detection ◽  
High Sensitivity ◽  
One Pot ◽  
Highly Efficient ◽  
Bimetallic Nanoclusters ◽  
Peroxidase Mimics ◽  
Sensitivity And Selectivity ◽  
Colorimetric Aptasensor

One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters possess highly-efficient peroxidase-like catalytic activity and are applied to design a colorimetric aptasensor for the protein detection with high sensitivity and selectivity.

Stable gold nanoparticles as a novel peroxidase mimic for colorimetric detection of cysteine

2016 ◽  
Vol 8 (11) ◽  
pp. 2494-2501 ◽  
Author(s):  
Rong Sheng Li ◽  
Hai Liu ◽  
Bin Bin Chen ◽  
Hong Zhi Zhang ◽  
Cheng Zhi Huang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Catalytic Activity ◽  
Colorimetric Detection ◽  
High Sensitivity ◽  
Peroxidase Mimic ◽  
Sensitivity And Selectivity ◽  
Blue Solution

In this work, stable gold nanoparticles (AuNPs) were prepared with good compatibility and favorable catalytic activity. They were developed as a peroxidase mimic for colorimetric detection of cysteine with a weakened blue solution, which supplied high sensitivity and selectivity.

scholarly journals Effective reduction of nitrophenols and colorimetric detection of Pb(ii) ions by Siraitia grosvenorii fruit extract capped gold nanoparticles

RSC Advances ◽  
2021 ◽  
Vol 11 (25) ◽  
pp. 15438-15448
Author(s):  
Van Thuan Le ◽  
Truong Giang Duong ◽  
Van Tan Le ◽  
Thanh Long Phan ◽  
Thi Lan Huong Nguyen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Catalytic Activity ◽  
Colorimetric Detection ◽  
High Sensitivity ◽  
Fruit Extract ◽  
Siraitia Grosvenorii ◽  
Effective Reduction ◽  
Sensitivity And Selectivity

Siraitia grosvenorii fruit extract capped AuNPs exhibited excellent catalytic activity in the reduction of nitrophenols and high sensitivity and selectivity for detection of Pb(ii) ions.

scholarly journals Copper (II) Ion-Modified Gold Nanoclusters as Peroxidase Mimetics for the Colorimetric Detection of Pyrophosphate

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5538
Author(s):  
Yunjing Shi ◽  
Jinjie Wang ◽  
Kun Mu ◽  
Suqin Liu ◽  
Guang Yang ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Detection Limit ◽  
Chemical Stability ◽  
Human Urine ◽  
Detection Method ◽  
Colorimetric Detection ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Sensitivity And Selectivity ◽  
Optimized Conditions

Copper (II) ions have been shown to greatly improve the chemical stability and peroxidase-like activity of gold nanoclusters (AuNCs). Since the affinity between Cu2+ and pyrophosphate (PPi) is higher than that between Cu2+ and AuNCs, the catalytic activity of AuNCs-Cu2+ decreases with the introduction of PPi. Based on this principle, a new colorimetric detection method of PPi with high sensitivity and selectivity was developed by using AuNCs-Cu2+ as a probe. Under optimized conditions, the detection limit of PPi was 0.49 nM with a linear range of 0.51 to 30,000 nM. The sensitivity of the method was three orders of magnitude higher than that of a fluorescence method using AuNCs-Cu2+ as the probe. Finally, the AuNCs-Cu2+ system was successfully applied to directly determine the concentration of PPi in human urine samples.

scholarly journals Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1207
Author(s):  
Hong Jae Cheon ◽  
Quynh Huong Nguyen ◽  
Moon Il Kim
Keyword(s):  
Magnetic Nanoparticles ◽  
High Sensitivity ◽  
High Specificity ◽  
Choline Oxidase ◽  
Fluorescent Detection ◽  
One Pot ◽  
Site Structure ◽  
Specificity And Sensitivity ◽  
Highly Sensitive ◽  
Peroxidase Mimics

Inspired by the active site structure of natural horseradish peroxidase having iron as a pivotal element with coordinated histidine residues, we have developed histidine coated magnetic nanoparticles (His@MNPs) with relatively uniform and small sizes (less than 10 nm) through one-pot heat treatment. In comparison to pristine MNPs and other amino acid coated MNPs, His@MNPs exhibited a considerably enhanced peroxidase-imitating activity, approaching 10-fold higher in catalytic reactions. With the high activity, His@MNPs then were exploited to detect the important neurotransmitter acetylcholine. By coupling choline oxidase and acetylcholine esterase with His@MNPs as peroxidase mimics, target choline and acetylcholine were successfully detected via fluorescent mode with high specificity and sensitivity with the limits of detection down to 200 and 100 nM, respectively. The diagnostic capability of the method is demonstrated by analyzing acetylcholine in human blood serum. This study thus demonstrates the potential of utilizing His@MNPs as peroxidase-mimicking nanozymes for detecting important biological and clinical targets with high sensitivity and reliability.

scholarly journals DESIGN AND SYNTHESIS OF MOLECULAR TWEEZER BASED ON 3-HYDROXYFLAVONE FOR THE DETECTION OF ATP

2017 ◽  
pp. 67-70
Author(s):  
O. Bugera ◽  
A. Netrebchuk ◽  
V. Pivovarenko
Keyword(s):  
Amino Acid ◽  
Hydrogen Bonds ◽  
Atmospheric Oxygen ◽  
High Sensitivity ◽  
Fluorescence Probes ◽  
Amino Acid Derivative ◽  
One Pot ◽  
Design And Synthesis ◽  
Sensitivity And Selectivity ◽  
Molecular Tweezer

Adenosine 5'-triphosphate (ATP) is known as a universal energy source and signaling mediator in numerous biological processes. Among the methods for its determination, molecular fluorescence probes occupy leading positions due to high sensitivity and selectivity. Recently we have shown that 31 of 33 tested flavones and quinolones of various structures give fluorescence response and can be effectively applied as the probes in aqueous solutions for detection of ATP in 1–50,000 μM range of its concentrations. To increase response parameters of a probe in respect to ATP we have synthesized N,N'-(butane-1,4-diyl)bis(2-((2-(4-(dimethylamino)phenyl)-3-hydroxy-4-oxo-4H-chromene-6-yl)oxy)acetamide, the molecular tweezer composed of two flavonol units connected by active linker. On our idea, being equipped by two planar platforms, the tweezershould demonstrate increased affinity and selectivity to ATP in a result of increased number of hydrogen bonds and increased stacking interactions. Having two NH-amide groups the amino acid linker will form hydrogen bonds with the phosphates of ATP, increasing the portion of probe-ATP complex population in the reporting conformation.In the four-step synthesis of this molecular device, starting from methyl 2-(3-acetyl-4-hydroxyphenoxy)acetate and N,N-dimethylaminobenzaldehyde, the conditions for the reaction of one-pot chalcone formation and its oxidative heterocyclization in the presence of an organic base were found, which resulted in the isolation of a target flavonol-amino acid derivative with high yields. We suggest that atmospheric oxygen was an oxidizer in this process. The obtained derivative was converted intotarget compound by dual condensation with 1,4-butane diamine.

scholarly journals Colorimetric Detection of Sulfide Anions via Redox-Modulated Surface Chemistry and Morphology of Au-Hg Nanorods

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Xiaotian Zhu ◽  
Chang Liu ◽  
Jie Liu
Keyword(s):  
Surface Chemistry ◽  
Colorimetric Assay ◽  
Colorimetric Detection ◽  
High Sensitivity ◽  
Localized Surface Plasmon ◽  
Wavelength Shift ◽  
Colorimetric Sensing ◽  
Leather Industry ◽  
Colorimetric Response ◽  
Sensitivity And Selectivity

A new colorimetric assay for the detection of sulfide anions with high sensitivity and selectivity is reported, utilizing Au-Hg alloy nanorods (Au-HgNRs) as probe. Au-HgNRs were prepared by modifying gold nanorods (AuNRs) with reducing agent and mercury ions. In an aqueous solution with sulfide anions, the formation of mercuric sulfide due to redox reaction between the amalgams and sulfide anions greatly changed the surface chemistry and morphology of the Au-HgNRs, leading to a red shift of the localized surface plasmon resonance (LSPR) absorption peak, accompanied by a change in colorimetric response. A good linear relationship was obtained between the LSPR peak wavelength shift and concentration of sulfide anion in the range of 1 × 10−5−1 × 10−4 mol/L. The selectivity of this method has been investigated by other anions. The colorimetric sensing system successfully detected sulfide in wastewater from leather industry.

scholarly journals Efficient Photoelectrochemical Water Splitting Reaction Using Electrodeposited Co3Se4 Catalys

2018 ◽  
Author(s):  
Yelyn Sim ◽  
Jude John ◽  
Subramani Surendran ◽  
Byeolee Moon ◽  
Uk Sim
Keyword(s):  
Catalytic Activity ◽  
Water Splitting ◽  
Noble Metal ◽  
Effective Area ◽  
Research Area ◽  
Photoelectrochemical Water Splitting ◽  
Photoelectrochemical Activity ◽  
One Pot ◽  
Noble Metal Catalysts ◽  
Highly Efficient

Photoelectrochemical water splitting is a promising field for sustainable energy production using hydrogen. Development of efficient catalysts is essential for resourceful hydrogen production. The most efficient catalysts reported to date have been extremely precious rare-earth metals. One of the biggest hurdles in this research area is the difficulty of developing highly efficient catalysts comparable to the noble metal catalysts. Here, we report that non-noble metal dichalcogenide (Co3Se4) catalysts made using a facile one-pot electrodeposition method, showed highly efficient photoelectrochemical activity on a Si photocathode. To enhance light collection and enlarge its surface area even further, we implemented surface nano-structuring on the Si surface. The nano-structured Si photoelectrode has an effective area greater than that of planar silicon and a wider absorption spectrum. Consequently, this approach exhibits reduced overvoltage as well as increased photo-catalytic activity. Such results show the importance of controlling the optimized interface between the surface structure of the photoelectrode and the electrodeposited co-catalyst on it to improve catalytic activity. This should enable other electrochemical reactions in a variety of energy conversion systems.

R-phycoerythrin proteins@ZIF-8 composite thin films for mercury ion detection

The Analyst ◽  
2019 ◽  
Vol 144 (12) ◽  
pp. 3892-3897 ◽  
Author(s):  
Xiaobin Wang ◽  
Zhishan Fang ◽  
Zhuoyi Li ◽  
Wen Ying ◽  
Danke Chen ◽  
...  
Keyword(s):  
Thin Films ◽  
Colorimetric Detection ◽  
High Sensitivity ◽  
Mercury Ion ◽  
Mercury Ions ◽  
Ion Detection ◽  
Composite Thin Films ◽  
Sensitivity And Selectivity ◽  
Mercury Ion Detection

Fluorescent R-phycoerythrin proteins were encapsulated into ZIF-8 thin films for colorimetric detection of mercury ions with high sensitivity and selectivity.

scholarly journals Immobilized antimony species on magnetite: a novel and highly efficient magnetically reusable nanocatalyst for direct and gram-scale reductive-coupling of nitroarenes to azoarenes

RSC Advances ◽  
2019 ◽  
Vol 9 (23) ◽  
pp. 13112-13121 ◽  
Author(s):  
Behzad Zeynizadeh ◽  
Fariba Faraji
Keyword(s):  
Catalytic Activity ◽  
Magnetic Nanoparticles ◽  
Nitro Compounds ◽  
Reductive Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
Aromatic Nitro Compounds ◽  
Aromatic Nitro

In this study, magnetic nanoparticles of Fe3O4@SbFx were synthesized. Then, the catalytic activity of Fe3O4@SbFx MNPs was highlighted by one-pot reductive-coupling of aromatic nitro compounds to the corresponding azoarene materials with NaBH4.

Colorimetric Detection of Hg(II) Sensor Based on Mos2 Nanosheets Acting as Peroxidase Mimics

2021 ◽  
Vol 37 (3) ◽  
pp. 679-682
Author(s):  
S. Kavitha ◽  
S. Mary Jelastin Kala ◽  
A. Anand Babu Christus
Keyword(s):  
Colorimetric Detection ◽  
High Sensitivity ◽  
Colorimetric Determination ◽  
X Ray Diffraction ◽  
Mos2 Nanosheets ◽  
Peroxidase Mimic ◽  
Sem Image ◽  
Peroxidase Mimics ◽  
Ft Ir

This paper presents colorimetric determination of Hg(II) based on MoS2 nanosheets with peroxidase mimics activity. The structure of the this sensor by the peroxidase mimic activity material of MoS2 nanosheets with TMB (Tetramethylbenzidine) solution, the colorimetric detection target of Hg(II) is determined by on-off mechanism using biomolecule of cysteine. The MoS2 nanosheets evaluated by X-ray diffraction, FT-IR and SEM image, confirms formation of a flower like structure. Our results shows that a simple colorimetric detection using peroxidase mimic mechanism can be used to MoS2 nanosheets and determine the Hg(II) in aqueous solution with high sensitivity (10 nM) comparable to those of other nanomaterials. The result suggests that MoS2 nanosheets is a promising new and simple colorimetric sensor for applications in environmental and biological applications.

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