Ionic liquid as porogen in the preparation of a polymer-based monolith for the separation of protein by high performance liquid chromatography

2015 ◽  
Vol 7 (2) ◽  
pp. 607-613 ◽  
Author(s):  
Ligai Bai ◽  
Jiafei Wang ◽  
Hang Zhang ◽  
Sha Liu ◽  
Junxiao Qin ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Atom Transfer Radical Polymerization ◽  
Radical Polymerization ◽  
High Performance ◽  
Atom Transfer

A novel polymer-based monolith for high performance liquid chromatography was developed by atom transfer radical polymerization (without the expensive complexing ligand) in which the ionic liquid (1-butyl-3-methylimidazolium chloride) was used as the porogen.

Preparation of a porous polymer monolithic column with an ionic liquid as a porogen and its applications for the separation of small molecules in high performance liquid chromatography

2015 ◽  
Vol 7 (18) ◽  
pp. 7879-7888 ◽  
Author(s):  
Jiafei Wang ◽  
Xiaoya Jiang ◽  
Hang Zhang ◽  
Sha Liu ◽  
Ligai Bai ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Small Molecules ◽  
Small Molecule ◽  
High Performance ◽  
Monolithic Column ◽  
Porous Polymer ◽  
Column Efficiency ◽  
Polymer Monolithic Column

A monolith based on an ionic liquid as a porogen was prepared to enhance the column efficiency of small molecule separation in HPLC.

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