A sensitive electrochemical biosensor for microRNA detection based on streptavidin–gold nanoparticles and enzymatic amplification

2014 ◽  
Vol 6 (9) ◽  
pp. 2889-2893 ◽  
Author(s):  
Yunlin Peng ◽  
Jianhui Jiang ◽  
Ruqin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Method ◽  
Electrochemical Biosensor ◽  
Enzymatic Amplification ◽  
Microrna Detection ◽  
Dual Signal Amplification

An electrochemical method for microRNA detection has been proposed with dual signal amplification based on streptavidin–gold nanoparticles and an enzyme.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

A novel electrochemical immunosensor based on dual signal amplification of gold nanoparticles and telomerase extension reaction

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Dual Signal Amplification

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.

Electrochemical biosensor for detection of pathogenic bacteria based on dual signal amplification of Cu3(PO4)2-mediated click chemistry and DNAzyme

The Analyst ◽  
2021 ◽  
Author(s):  
Hongguo Wei ◽  
Jiayu Wan ◽  
Shengjun Bu ◽  
Wenguang Zhang ◽  
Ma Li ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Magnetic Separation ◽  
Concanavalin A ◽  
Signal Amplification ◽  
Pathogenic Bacteria ◽  
Electrochemical Biosensor ◽  
Inorganic Hybrid ◽  
Highly Sensitive ◽  
Antibody Conjugates ◽  
Dual Signal Amplification

A novel electrochemical biosensor for detecting pathogenic bacteria was designed based on specific magnetic separation and highly sensitive click chemistry. Instead of enzyme-antibody conjugates, organic-inorganic hybrid nanoflowers (Concanavalin A (Con...

scholarly journals Optimization of the Electrodeposition of Gold Nanoparticles for the Application of Highly Sensitive, Label-Free Biosensor

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 50 ◽  
Author(s):  
Hao-Chun Chiang ◽  
Yanyan Wang ◽  
Qi Zhang ◽  
Kalle Levon
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Aqueous Electrolyte ◽  
Label Free ◽  
Reduction Step ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Amperometric Glucose Biosensors ◽  
Aunp Surface

A highly sensitive electrochemical biosensor with a signal amplification platform of electrodeposited gold nanoparticle (AuNP) has been developed and characterized. The sizes of the synthesized AuNP were found to be critical for the performance of biosensor in which the sizes were dependent on HAuCl4 and acid concentrations; as well as on scan cycles and scan rates in the gold electro-reduction step. Systematic investigations of the adsorption of proteins with different sizes from aqueous electrolyte solution onto the electrodeposited AuNP surface were performed with a potentiometric method and calibrated by design of experiment (DOE). The resulting amperometric glucose biosensors was demonstrated to have a low detection limit (> 50 μM) and a wide linear range after optimization with AuNP electrodeposition.

Reduced graphene oxide-gold nanoparticles-catalase-based dual signal amplification strategy in a spatial-resolved ratiometric electrochemiluminescence immunoassay

The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Jun-Tao Cao ◽  
Xiao-Long Fu ◽  
Fu-Rao Liu ◽  
Shu-Wei Ren ◽  
Yan-Ming Liu
Keyword(s):  
Gold Nanoparticles ◽  
Cardiac Troponin ◽  
Signal Amplification ◽  
Troponin I ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Reduced Graphene ◽  
Electrochemiluminescence Immunoassay ◽  
Amplification Strategy ◽  
Dual Signal Amplification

A novel spatial-resolved electrochemiluminescent (ECL) ratiometry for cardiac troponin I (cTnI) analysis was developed using resonance energy transfer (RET) and a coreactant consumption strategy for signal amplification.

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