13C-engineered carbon quantum dots for in vivo magnetic resonance and fluorescence dual-response

The Analyst ◽  
2014 ◽  
Vol 139 (20) ◽  
pp. 5134-5139 ◽  
Author(s):  
Yang Xu ◽  
Yu-Hao Li ◽  
Yue Wang ◽  
Jian-Lin Cui ◽  
Xue-Bo Yin ◽  
...  

13C-engineered carbon quantum dots (13C-QDs) were used as magnetic resonance (MR) and fluorescence dual-response probe.

2017 ◽  
Vol 41 (9) ◽  
pp. 3422-3431 ◽  
Author(s):  
Ai Gao ◽  
Yan-Fei Kang ◽  
Xue-Bo Yin

Hybrid carbon quantum dots were prepared with p-phenylenediamine, diethylene triamine pentacetic acid, and Gd3+ hydrothermally. Their excitation-independent red fluorescence and magnetic resonance dual-response was confirmed with zebrafish and mice as models.


2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.


2016 ◽  
Vol 4 (38) ◽  
pp. 6366-6372 ◽  
Author(s):  
Fengshou Wu ◽  
Huifang Su ◽  
Xunjin Zhu ◽  
Kai Wang ◽  
Zhenfeng Zhang ◽  
...  

Facile preparation of lanthanide hybridized carbon quantum dots (Ln-CQDs) and their potential for visible/NIR bioimagingin vivo.


2008 ◽  
pp. 5764 ◽  
Author(s):  
Takashi Jin ◽  
Yoshichika Yoshioka ◽  
Fumihiko Fujii ◽  
Yutaka Komai ◽  
Junji Seki ◽  
...  

2014 ◽  
Vol 20 (19) ◽  
pp. 5640-5648 ◽  
Author(s):  
Yi-Fan Huang ◽  
Xin Zhou ◽  
Rong Zhou ◽  
Hong Zhang ◽  
Kai-Bin Kang ◽  
...  

Neurosurgery ◽  
2009 ◽  
Vol 64 (6) ◽  
pp. 1015-1028 ◽  
Author(s):  
Alexander A. Khalessi ◽  
Charles Y. Liu ◽  
Michael L.J. Apuzzo

Abstract THIS ARTICLE REPRESENTS the first of a 2-part exploration of quantum dots (Qdots) and their application to neurological surgery. Spanning from materials science to immunology, this initial review traces the marriage of imaging physics to biochemical specificity. Qdot science now stands poised to dramatically advance the diagnosis and therapy of neurosurgical conditions. Qdot research efforts currently involve several disciplines; this comprehensive review therefore considers multiple fields of inquiry. This first installment discusses 1) Qdot physical properties, 2) established biological and in vivo properties, 3) magnetic resonance imaging applications, and (4) existing cardiovascular and oncologic research. Finally, this review establishes the existing bounds of Qdot possibilities. The second concept article details future endovascular diagnostic and therapeutic methods derived from these seminal advances.


Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9264-9272 ◽  
Author(s):  
Gary Sitbon ◽  
Sophie Bouccara ◽  
Mariana Tasso ◽  
Aurélie Francois ◽  
Lina Bezdetnaya ◽  
...  

Cadmium-free quantum dots doped with Mn2+ions show promising results forin vivobimodal MRI and NIR fluorescence imaging.


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