Dye-enhanced graphene oxide for photothermal therapy and photoacoustic imaging

2013 ◽  
Vol 1 (42) ◽  
pp. 5762 ◽  
Author(s):  
Yi-Wei Wang ◽  
Yu-Ying Fu ◽  
Qiaoli Peng ◽  
Shan-Shan Guo ◽  
Gang Liu ◽  
...  
Biomaterials ◽  
2013 ◽  
Vol 34 (21) ◽  
pp. 5236-5243 ◽  
Author(s):  
Zonghai Sheng ◽  
Liang Song ◽  
Jiaxiang Zheng ◽  
Dehong Hu ◽  
Meng He ◽  
...  

2017 ◽  
Vol 5 (9) ◽  
pp. 1846-1855 ◽  
Author(s):  
Yixue Zhang ◽  
Hao Zhang ◽  
Yanke Wang ◽  
Huixia Wu ◽  
Bo Zeng ◽  
...  

GO/Bi2Se3/PVP nanocomposites fabricated by a one-pot solvothermal method show good performance in CT/photoacoustic imaging and photothermal therapy.


2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Xibo Ma ◽  
Yushen Jin ◽  
Yi Wang ◽  
Shuai Zhang ◽  
Dong Peng ◽  
...  

Tumor cell complete extinction is a crucial measure to evaluate antitumor efficacy. The difficulties in defining tumor margins and finding satellite metastases are the reason for tumor recurrence. A synergistic method based on multimodality molecular imaging needs to be developed so as to achieve the complete extinction of the tumor cells. In this study, graphene oxide conjugated with gold nanostars and chelated with Gd through 1,4,7,10-tetraazacyclododecane-N,N′,N,N′-tetraacetic acid (DOTA) (GO-AuNS-DOTA-Gd) were prepared to target HCC-LM3-fLuc cells and used for therapy. For subcutaneous tumor, multimodality molecular imaging including photoacoustic imaging (PAI) and magnetic resonance imaging (MRI) and the related processing techniques were used to monitor the pharmacokinetics process of GO-AuNS-DOTA-Gd in order to determine the optimal time for treatment. For orthotopic tumor, MRI was used to delineate the tumor location and margin in vivo before treatment. Then handheld photoacoustic imaging system was used to determine the tumor location during the surgery and guided the photothermal therapy. The experiment result based on orthotopic tumor demonstrated that this synergistic method could effectively reduce tumor residual and satellite metastases by 85.71% compared with the routine photothermal method without handheld PAI guidance. These results indicate that this multimodality molecular imaging-guided photothermal therapy method is promising with a good prospect in clinical application.


2021 ◽  
Vol 4 (2) ◽  
pp. 2019-2029
Author(s):  
Li-Peng Zhang ◽  
Lin Kang ◽  
Xianqiang Li ◽  
Shiyang Liu ◽  
Tianlong Liu ◽  
...  

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document