Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer

2014 ◽  
Vol 5 (5) ◽  
pp. 1860-1868 ◽  
Author(s):  
Takayuki Doi ◽  
Masahito Yoshida ◽  
Kosuke Ohsawa ◽  
Kazuo Shin-ya ◽  
Motoki Takagi ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Protein Interaction ◽  
Synthesis And Characterization ◽  
Protein Protein Interaction

We have characterized the inhibition of the protein–protein interaction of the homodimer of proteasome assembling chaperone (PAC) 3 with thielocin B1.

Synthesis and characterization of a series of novel phenol- and polyphenol-based glycerolipids

2006 ◽  
Vol 84 (10) ◽  
pp. 1411-1415 ◽  
Author(s):  
Rolf Schmidt ◽  
Joseph G Carrigan ◽  
Christine E DeWolf
Keyword(s):  
Hydrogen Bonding ◽  
Chain Length ◽  
Protein Interaction ◽  
Building Block ◽  
Synthesis And Characterization ◽  
Synthetic Route ◽  
Substitution Pattern ◽  
Lipid Protein Interaction ◽  
Block Approach

A building block approach was used to design a modular synthetic route for the preparation of novel glycerolipids with phenolic and polyphenolic headgroups. Based on this scheme, it is possible to vary the substitution pattern of the headgroup, the stereochemistry of the backbone, and the length of the sidechains. Five glycerolipids with different headgroups and identical backbone stereochemistry and chain length have been prepared.Key words: glycerolipid, polyphenol, hydrogen bonding, lipid-protein interaction, self-adhering.

scholarly journals Protein-protein interaction analysis for functional characterization of helicases

Methods ◽  
2016 ◽  
Vol 108 ◽  
pp. 56-64 ◽  
Author(s):  
Boris L. Zybailov ◽  
Alicia K. Byrd ◽  
Galina V. Glazko ◽  
Yasir Rahmatallah ◽  
Kevin D. Raney
Keyword(s):  
Protein Interaction ◽  
Interaction Analysis ◽  
Functional Characterization ◽  
Protein Protein Interaction

scholarly journals Total Synthesis and Characterization of 7-Hypoquinuclidonium Tetrafluoroborate and 7-Hypoquinuclidone BF3 Complex

2016 ◽  
Vol 138 (3) ◽  
pp. 969-974 ◽  
Author(s):  
Marc Liniger ◽  
David G. VanderVelde ◽  
Michael K. Takase ◽  
Mona Shahgholi ◽  
Brian M. Stoltz
Keyword(s):  
Total Synthesis ◽  
Synthesis And Characterization

scholarly journals Characterization of Protein-Protein Interaction Interfaces from a Single Species

PLoS ONE ◽  
2011 ◽  
Vol 6 (6) ◽  
pp. e21053 ◽  
Author(s):  
David Talavera ◽  
David L. Robertson ◽  
Simon C. Lovell
Keyword(s):  
Protein Interaction ◽  
Single Species ◽  
Protein Protein Interaction
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