scholarly journals Protein-protein interaction analysis for functional characterization of helicases

Methods ◽  
2016 ◽  
Vol 108 ◽  
pp. 56-64 ◽  
Author(s):  
Boris L. Zybailov ◽  
Alicia K. Byrd ◽  
Galina V. Glazko ◽  
Yasir Rahmatallah ◽  
Kevin D. Raney
Author(s):  
Hon Nian Chua ◽  
Limsoon Wong

Functional characterization of genes and their protein products is essential to biological and clinical research. Yet, there is still no reliable way of assigning functional annotations to proteins in a high-throughput manner. In this article, the authors provide an introduction to the task of automated protein function prediction. They discuss about the motivation for automated protein function prediction, the challenges faced in this task, as well as some approaches that are currently available. In particular, they take a closer look at methods that use protein-protein interaction for protein function prediction, elaborating on their underlying techniques and assumptions, as well as their strengths and limitations.


Author(s):  
Hon Nian Chua ◽  
Limsoon Wong

Functional characterization of genes and their protein products is essential to biological and clinical research. Yet, there is still no reliable way of assigning functional annotations to proteins in a high-throughput manner. In this chapter, the authors provide an introduction to the task of automated protein function prediction. They discuss about the motivation for automated protein function prediction, the challenges faced in this task, as well as some approaches that are currently available. In particular, they take a closer look at methods that use protein-protein interaction for protein function prediction, elaborating on their underlying techniques and assumptions, as well as their strengths and limitations.


2007 ◽  
Vol 128 (2) ◽  
pp. 354-361 ◽  
Author(s):  
Y KUMADA ◽  
C ZHAO ◽  
R ISHIMURA ◽  
H IMANAKA ◽  
K IMAMURA ◽  
...  

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