scholarly journals Utilizing the bioorthogonal base-pairing system ofl-DNA to design ideal DNA nanocarriers for enhanced delivery of nucleic acid cargos

2014 ◽  
Vol 5 (4) ◽  
pp. 1533-1537 ◽  
Author(s):  
Kyoung-Ran Kim ◽  
Taemin Lee ◽  
Byeong-Su Kim ◽  
Dae-Ro Ahn
Keyword(s):  
2014 ◽  
Vol 10 ◽  
pp. 2131-2138 ◽  
Author(s):  
Keunsoo Kim ◽  
Venkateshwarlu Punna ◽  
Phaneendrasai Karri ◽  
Ramanarayanan Krishnamurthy

IsoGNA, an isomer of glycerol nucleic acid GNA, is a flexible (acyclic) nucleic acid with bases directly attached to its linear backbone. IsoGNA exhibits (limited) base-pairing properties which are unique compared to other known flexible nucleic acids. Herein, we report on the details of the preparation of isoGNA phosphoramidites and an alternative route for the synthesis of the adenine derivative. The synthetic improvements described here enable an easy access to isoGNA and allows for the further exploration of this structural unit in oligonucleotide chemistry thereby spurring investigations of its usefulness and applicability.


2002 ◽  
Vol 59 (12) ◽  
pp. 792-799
Author(s):  
Takahiro HARADA ◽  
Takashi MIYAHARA ◽  
Naotoshi NAKASHIMA ◽  
Kazue KURIHARA

1991 ◽  
Vol 95 (4) ◽  
pp. 1530-1532 ◽  
Author(s):  
Anthony Harriman ◽  
Darren J. Magda ◽  
Jonathan L. Sessler

1992 ◽  
Vol 20 (19) ◽  
pp. 5011-5016 ◽  
Author(s):  
Richard Lavery ◽  
Krystyna Zakrzewska ◽  
Jian-Sheng Sun ◽  
Stephen C. Harvey

CrystEngComm ◽  
2017 ◽  
Vol 19 (37) ◽  
pp. 5679-5685 ◽  
Author(s):  
Elizabeth S. Koch ◽  
Kelly A. McKenna ◽  
Hyo Jung Kim ◽  
Victor G. Young ◽  
Jennifer A. Swift

Cocrystal design through DNA-type base pairing between a nucleic acid and complementary heterocycles.


Biopolymers ◽  
1994 ◽  
Vol 34 (12) ◽  
pp. 1573-1581 ◽  
Author(s):  
G. Raghunathan ◽  
H. Todd Miles ◽  
V. Sasisekharan

1999 ◽  
Vol 78 (1-2) ◽  
pp. 183-193 ◽  
Author(s):  
Ray Luo ◽  
Martha S. Head ◽  
James A. Given ◽  
Michael K. Gilson

2006 ◽  
Vol 118 (22) ◽  
pp. 3705-3709 ◽  
Author(s):  
Christelle Dupouy ◽  
Nathalie Iché-Tarrat ◽  
Marie-Pierre Durrieu ◽  
Frédéric Rodriguez ◽  
Jean-Marc Escudier ◽  
...  

2021 ◽  
Author(s):  
Colin Swenson ◽  
Hershel H Lackey ◽  
Eric James Reece ◽  
Joel M. Harris ◽  
Jennifer Heemstra ◽  
...  

Peptide nucleic acid (PNA) is a unique synthetic nucleic acid analog that has been adopted for use in many biological applications. These applications rely upon the robust Franklin-Watson-Crick base pairing...


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