Parallel nucleic acid helices with hoogsteen base pairing: Symmetry and structure

Biopolymers ◽  
1994 ◽  
Vol 34 (12) ◽  
pp. 1573-1581 ◽  
Author(s):  
G. Raghunathan ◽  
H. Todd Miles ◽  
V. Sasisekharan
2014 ◽  
Vol 10 ◽  
pp. 2131-2138 ◽  
Author(s):  
Keunsoo Kim ◽  
Venkateshwarlu Punna ◽  
Phaneendrasai Karri ◽  
Ramanarayanan Krishnamurthy

IsoGNA, an isomer of glycerol nucleic acid GNA, is a flexible (acyclic) nucleic acid with bases directly attached to its linear backbone. IsoGNA exhibits (limited) base-pairing properties which are unique compared to other known flexible nucleic acids. Herein, we report on the details of the preparation of isoGNA phosphoramidites and an alternative route for the synthesis of the adenine derivative. The synthetic improvements described here enable an easy access to isoGNA and allows for the further exploration of this structural unit in oligonucleotide chemistry thereby spurring investigations of its usefulness and applicability.


Nature ◽  
2004 ◽  
Vol 430 (6997) ◽  
pp. 377-380 ◽  
Author(s):  
Deepak T. Nair ◽  
Robert E. Johnson ◽  
Satya Prakash ◽  
Louise Prakash ◽  
Aneel K. Aggarwal

2008 ◽  
Vol 21 (9) ◽  
pp. 1795-1805 ◽  
Author(s):  
Ganesh Shanmugam ◽  
Ivan D. Kozekov ◽  
F. Peter Guengerich ◽  
Carmelo J. Rizzo ◽  
Michael P. Stone

2002 ◽  
Vol 59 (12) ◽  
pp. 792-799
Author(s):  
Takahiro HARADA ◽  
Takashi MIYAHARA ◽  
Naotoshi NAKASHIMA ◽  
Kazue KURIHARA

2000 ◽  
Vol 5 (5) ◽  
pp. 603-611 ◽  
Author(s):  
Jens Müller ◽  
Markus Drumm ◽  
Marc Boudvillain ◽  
Marc Leng ◽  
Einar Sletten ◽  
...  

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