Tailoring surface plasmons of high-density gold nanostar assemblies on metal films for surface-enhanced Raman spectroscopy

Nanoscale ◽  
2014 ◽  
Vol 6 (1) ◽  
pp. 616-623 ◽  
Author(s):  
Jiwon Lee ◽  
Bo Hua ◽  
Seungyoung Park ◽  
Minjeong Ha ◽  
Youngsu Lee ◽  
...  
Nanomaterials ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 1561 ◽  
Author(s):  
Maria João Oliveira ◽  
Miguel P. de Almeida ◽  
Daniela Nunes ◽  
Elvira Fortunato ◽  
Rodrigo Martins ◽  
...  

Immunoassays using Surface-Enhanced Raman Spectroscopy are especially interesting on account not only of their increased sensitivity, but also due to its easy translation to point-of-care formats. The bases for these assays are bioconjugates of polyclonal antibodies and anisotropic gold nanoparticles functionalized with a Raman reporter. These bioconjugates, once loaded with the antigen analyte, can react on a sandwich format with the same antibodies immobilized on a surface. This surface can then be used for detection, on a microfluidics or immunochromatographic platform. Here, we have assembled bioconjugates of gold nanostars functionalized with 4-mercaptobenzoic acid, and anti-horseradish peroxidase antibodies. The assembly was by simple incubation, and agarose gel electrophoresis determined a high gold nanostar to antibody binding constant. The functionality of the bioconjugates is easy to determine since the respective antigen presents peroxidase enzymatic activity. Furthermore, the chosen antibody is a generic immunoglobulin G (IgG) antibody, opening the application of these principles to other antibody-antigen systems. Surface-Enhanced Raman Spectroscopy analysis of these bioconjugates indicated antigen detection down to 50 µU of peroxidase activity. All steps of conjugation were fully characterized by ultraviolet-visible spectroscopy, dynamic light scattering, ζ -Potential, scanning electron microscopy, and agarose gel electrophoresis. Based on the latter technique, a proof-of-concept was established for the proposed immunoassay.


2010 ◽  
Vol 114 (50) ◽  
pp. 21953-21959 ◽  
Author(s):  
Mingliang Jin ◽  
Vishnu Pully ◽  
Cees Otto ◽  
Albert van den Berg ◽  
Edwin T. Carlen

1994 ◽  
Vol 01 (04) ◽  
pp. 557-559 ◽  
Author(s):  
W. AKEMANN ◽  
A. OTTO

The adsorption of CO 2 to surfaces of pure and promoted noble metal films is investigated at 40 K using surface-enhanced Raman spectroscopy (SERS). The data indicate nonactivated adsorption on silver and gold, activated adsorption on potassium and a coexistence of activated and nonactivated adsorption on copper and potassium-doped silver. The activated species is identified to be a [Formula: see text] surface anion.


RSC Advances ◽  
2016 ◽  
Vol 6 (50) ◽  
pp. 44163-44169 ◽  
Author(s):  
A. I. Radu ◽  
Ye. Ye. Ussembayev ◽  
M. Jahn ◽  
U. S. Schubert ◽  
K. Weber ◽  
...  

Commercially available HD-DVD templates have been used to theoretically predict the occurrence of surface plasmons supermodes which improve the detection of surface enhanced Raman signals.


2016 ◽  
Vol 27 (49) ◽  
pp. 49LT01 ◽  
Author(s):  
Mingliang Jin ◽  
Yunfei Zhu ◽  
Albert van den Berg ◽  
Zhang Zhang ◽  
Guofu Zhou ◽  
...  

2007 ◽  
Vol 129 (20) ◽  
pp. 6378-6379 ◽  
Author(s):  
Gary Braun ◽  
Seung Joon Lee ◽  
Mark Dante ◽  
Thuc-Quyen Nguyen ◽  
Martin Moskovits ◽  
...  

2021 ◽  
Author(s):  
Lihua Xu ◽  
Qianqian Ding

The Fe3O4@Au nanostar, whose anisotropic shape couples the plasmons focused on the magnetic core with the branches of gold shell, makes it hold promise for surface enhanced Raman spectroscopy (SERS)...


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