High-Density Periodic Arrays of Self-Aligned Subwavelength Nanopyramids for Surface-Enhanced Raman Spectroscopy

2010 ◽  
Vol 114 (50) ◽  
pp. 21953-21959 ◽  
Author(s):  
Mingliang Jin ◽  
Vishnu Pully ◽  
Cees Otto ◽  
Albert van den Berg ◽  
Edwin T. Carlen
2016 ◽  
Vol 27 (49) ◽  
pp. 49LT01 ◽  
Author(s):  
Mingliang Jin ◽  
Yunfei Zhu ◽  
Albert van den Berg ◽  
Zhang Zhang ◽  
Guofu Zhou ◽  
...  

Nanoscale ◽  
2014 ◽  
Vol 6 (1) ◽  
pp. 616-623 ◽  
Author(s):  
Jiwon Lee ◽  
Bo Hua ◽  
Seungyoung Park ◽  
Minjeong Ha ◽  
Youngsu Lee ◽  
...  

2021 ◽  
Author(s):  
Lihua Xu ◽  
Qianqian Ding

The Fe3O4@Au nanostar, whose anisotropic shape couples the plasmons focused on the magnetic core with the branches of gold shell, makes it hold promise for surface enhanced Raman spectroscopy (SERS)...


2016 ◽  
Vol 27 (16) ◽  
pp. 165304 ◽  
Author(s):  
Mengyang Kang ◽  
Xiaoyan Zhang ◽  
Liwei Liu ◽  
Qingwei Zhou ◽  
Mingliang Jin ◽  
...  

Biosensors ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 181
Author(s):  
Giovanni Marinaro ◽  
Maria Laura Coluccio ◽  
Francesco Gentile

The method of realizing nanostructures using porous alumina templates has attracted interest due to the precise geometry and cheap cost of nanofabrication. In this work, nanoporous alumina membranes were utilized to realize a forest of nanowires, providing a bottom-up nanofabrication method suitable for surface-enhanced Raman spectroscopy (SERS). Gold and iron were electroplated through the straight channels of the membrane. The resulting nanowires are, indeed, made of an active element for plasmonic resonance and SERS as the hexagonal distribution of the nanowires and the extreme high density of the nanowires allows to excite the plasmon and detect the Raman signal. The method to reduce the distance between pores and, consequently, the distance of the nanowires after electrodeposition is optimized here. Indeed, it has been predicted that the light intensity enhancement factor is up to 1012 when the gap is small than 10 nm. Measurements of Raman signal of thiol groups drying on the gold nanowires show that the performance of the device is improved. As the thiol group can be linked to proteins, the device has the potential of a biosensor for the detection of a few biomolecules. To assess the performance of the device and demonstrate its ability to analyze biological solutions, we used it as SERS substrates to examine solutions of IgG in low abundance ranges. The results of the test indicate that the sensor can convincingly detect biomolecules in physiologically relevant ranges.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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