scholarly journals Structure and properties of metal complexes of a pyridine based oxazolidinone synthesized by atmospheric CO2 fixation

2014 ◽  
Vol 38 (2) ◽  
pp. 817-826 ◽  
Author(s):  
Amrita Sarkar ◽  
Sudipta Bhattacharyya ◽  
Suman Kr Dey ◽  
Subhendu Karmakar ◽  
Arindam Mukherjee
Keyword(s):  
Metal Complexes ◽  
Co2 Fixation ◽  
Palladium Complexes ◽  
Atmospheric Co2 ◽  
Structure And Properties ◽  
Platinum And Palladium Complexes

Copper, platinum and palladium complexes of an oxazolidinone ligand show potential in catalysis or cytotoxicity, depending on the metal incorporated.

scholarly journals Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2860
Author(s):  
Robert Czarnomysy ◽  
Dominika Radomska ◽  
Anna Muszyńska ◽  
Justyna Magdalena Hermanowicz ◽  
Izabela Prokop ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Transition Metal ◽  
Metal Complexes ◽  
Cancer Cells ◽  
Transition Metal Complexes ◽  
Breast Cancer Cells ◽  
Palladium Complexes ◽  
Anticancer Activities ◽  
Platinum And Palladium Complexes ◽  
Mcf 7

Novel transition metal complexes (Au, Pd, Pt) with berenil and 2-(1-methyl-5-nitroimidazol-2-yl)ethanol were obtained through two-step synthesis. The cytotoxicity assay against MCF-7 and MDA-MB-231 breast cancer cells revealed that novel platinum and palladium complexes cause a reduction on the viability of MCF-7 and MDA-MB-231 breast cancer cells to a greater extent than cisplatin. The complexes showed lower cytotoxicity on normal MCF-10A human breast epithelial cells than on tumor cells. Furthermore, we observed that these complexes selectively concentrate in tumor cell mitochondria due to the characteristic for these cells increased membrane potential that may explain their increased proapoptotic activity. The activity of the synthesized compounds against topoisomerase type IIα and their increased impact on DNA defragmentation also were documented. The novel complexes also induced autophagosome changes and inhibited tumor growth in xenograft models (established using breast cancer cells).

Platinum and palladium complexes of the type [M(EPh)2(dppe)] (EO, S, Se)

1993 ◽  
Vol 206 (1) ◽  
pp. 123-125 ◽  
Author(s):  
Xu Chongfu ◽  
Jeffrey W. Siria ◽  
Gordon K. Anderson
Keyword(s):  
Palladium Complexes ◽  
Platinum And Palladium Complexes

Gyroscope-Like Platinum and Palladium Complexes with Trans-Spanning Bis(pyridine) Ligands

2012 ◽  
Vol 31 (7) ◽  
pp. 2854-2877 ◽  
Author(s):  
Paul D. Zeits ◽  
Giovanni Pietro Rachiero ◽  
Frank Hampel ◽  
Joseph H. Reibenspies ◽  
John A. Gladysz
Keyword(s):  
Palladium Complexes ◽  
Pyridine Ligands ◽  
Platinum And Palladium Complexes
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