One-pot two-step mechanochemical synthesis: ligand and complex preparation without isolating intermediates

2014 ◽  
Vol 16 (3) ◽  
pp. 1374-1382 ◽  
Author(s):  
Michael Ferguson ◽  
Nicola Giri ◽  
Xu Huang ◽  
David Apperley ◽  
Stuart L. James
Keyword(s):  
Mechanochemical Synthesis ◽  
One Pot ◽  
Complex Preparation

Mechanochemical synthesis of an Eu(III) complex. Preparation and Luminescence Properties of PMMA:[C42H38N5O19Eu] Hybrid Films

Polyhedron ◽  
2015 ◽  
Vol 85 ◽  
pp. 10-14 ◽  
Author(s):  
Sara Rodríguez ◽  
Perla Elizondo ◽  
Sylvain Bernès ◽  
Nancy Pérez ◽  
Ricardo Bustos ◽  
...  
Keyword(s):  
Mechanochemical Synthesis ◽  
Luminescence Properties ◽  
Hybrid Films ◽  
Complex Preparation

scholarly journals Study of the Two Steps and One-Pot Two-Step Mechanochemical Synthesis of Annulated 1,2,4-Triazoles

2020 ◽  
Vol 8 (8) ◽  
pp. 3114-3125
Author(s):  
Lori Gonnet ◽  
Christiane André-Barrès ◽  
Brigitte Guidetti ◽  
Alain Chamayou ◽  
Christophe Menendez ◽  
...  
Keyword(s):  
Mechanochemical Synthesis ◽  
One Pot

scholarly journals Assembly of fully substituted triazolochromenes via a novel multicomponent reaction or mechanochemical synthesis

2018 ◽  
Vol 14 ◽  
pp. 2689-2697 ◽  
Author(s):  
Robby Vroemans ◽  
Yenthel Verhaegen ◽  
My Tran Thi Dieu ◽  
Wim Dehaen
Keyword(s):  
Multicomponent Reaction ◽  
Mechanochemical Synthesis ◽  
Solvent Free ◽  
Viable Alternative ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Biologically Relevant ◽  
Metal Free ◽  
Organic Azides ◽  
Solvent Free Conditions

A new metal-free one-pot three-component procedure towards fully substituted triazolochromenes has been developed, starting from commercially available materials. Salicylaldehydes and nitroalkenes were reacted under solvent-free conditions, followed by a 1,3-dipolar cycloaddition of the intermediate 3-nitro-2H-chromenes with organic azides in a one-pot two-step sequence. The triazolochromenes were formed with complete regioselectivity and new biologically relevant structures were synthesized via extension of the developed procedure and via postfunctionalization. The mechanochemical synthesis was carried out for several salicylaldehydes and gave a clear improvement in the yield of the corresponding triazolochromenes and consequently showed to be a viable alternative for solid salicylaldehydes.

scholarly journals Mechanochemical synthesis of magnesium-based carbon nucleophiles in air and their use in organic synthesis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Rina Takahashi ◽  
Anqi Hu ◽  
Pan Gao ◽  
Yunpeng Gao ◽  
Yadong Pang ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Mechanochemical Synthesis ◽  
Nucleophilic Addition ◽  
Reaction Times ◽  
Grignard Reagents ◽  
Coupling Reactions ◽  
One Pot ◽  
Carbon Nucleophiles ◽  
Cross Coupling Reactions ◽  
Solvent Free Conditions

AbstractSince the discovery of Grignard reagents in 1900, the nucleophilic addition of magnesium-based carbon nucleophiles to various electrophiles has become one of the most powerful, versatile, and well-established methods for the formation of carbon−carbon bonds in organic synthesis. Grignard reagents are typically prepared via reactions between organic halides and magnesium metal in a solvent. However, this method usually requires the use of dry organic solvents, long reaction times, strict control of the reaction temperature, and inert-gas-line techniques. Despite the utility of Grignard reagents, these requirements still represent major drawbacks from both an environmental and an economic perspective, and often cause reproducibility problems. Here, we report the general mechanochemical synthesis of magnesium-based carbon nucleophiles (Grignard reagents in paste form) in air using a ball milling technique. These nucleophiles can be used directly for one-pot nucleophilic addition reactions with various electrophiles and nickel-catalyzed cross-coupling reactions under solvent-free conditions.

scholarly journals Mechanochemical synthesis of N-doped porous carbon at room temperature

Nanoscale ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 4712-4718 ◽  
Author(s):  
Mirian Elizabeth Casco ◽  
Sebastian Kirchhoff ◽  
Desirée Leistenschneider ◽  
Marcus Rauche ◽  
Eike Brunner ◽  
...  
Keyword(s):  
Mechanochemical Synthesis ◽  
Porous Carbon ◽  
Ball Mill ◽  
Room Temperature ◽  
Planetary Ball Mill ◽  
Porous Carbons ◽  
One Pot

One-pot mechanochemical synthesis of N-doped porous carbons at room temperature using a planetary ball mill.

Nickel-substituted zeolitic imidazolate frameworks for time-resolved alcohol sensing and photocatalysis under visible light

2014 ◽  
Vol 2 (16) ◽  
pp. 5724-5729 ◽  
Author(s):  
Rui Li ◽  
Xiaoqian Ren ◽  
Hongwei Ma ◽  
Xiao Feng ◽  
Zhengguo Lin ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Visible Light ◽  
Mechanochemical Synthesis ◽  
Zeolitic Imidazolate Frameworks ◽  
One Pot ◽  
Time Resolved ◽  
Photo Catalytic Activity ◽  
Nickel Clusters ◽  
Ni Clusters

A facile strategy has been developed to introduce six-coordinated nickel clusters to zinc-based ZIF-8 structure via a one-pot mechanochemical synthesis. This Ni-substituted ZIF-8 can selectively pick different alcohol molecules and undergo a de-coordination to form stable four-coordinated Ni clusters which shows exceptional photo-catalytic activity.

scholarly journals One-pot multistep mechanochemical synthesis of fluorinated pyrazolones

2017 ◽  
Vol 13 ◽  
pp. 1950-1956 ◽  
Author(s):  
Joseph L Howard ◽  
William Nicholson ◽  
Yerbol Sagatov ◽  
Duncan L Browne
Keyword(s):  
Mechanochemical Synthesis ◽  
Sustainability Metrics ◽  
One Pot ◽  
Solid Form ◽  
Solventless Reaction

Solventless mechanochemical synthesis represents a technique with improved sustainability metrics compared to solvent-based processes. Herein, we describe a methodical process to run one solventless reaction directly into another through multistep mechanochemistry, effectively amplifying the solvent savings. The approach has to consider the solid form of the materials and compatibility of any auxiliary used. This has culminated in the development of a two-step, one-jar protocol for heterocycle formation and subsequent fluorination that has been successfully applied across a range of substrates, resulting in 12 difluorinated pyrazolones in moderate to excellent yields.

One‐Pot Mechanochemical Synthesis of Mono‐ and Bis‐Indolylquinones via Solvent‐Free Multiple Bond‐Forming Processes

ChemSusChem ◽  
2021 ◽  
Author(s):  
Marta Piquero ◽  
Cristina Font ◽  
Natalia Gullón ◽  
Pilar López‐Alvarado ◽  
J. Carlos Menéndez
Keyword(s):  
Mechanochemical Synthesis ◽  
Multiple Bond ◽  
Solvent Free ◽  
One Pot ◽  
Bond Forming

One-pot mechanochemical synthesis to encapsulate functional guests into a metal-organic framework for proton conduction

2021 ◽  
Author(s):  
Yang Wang ◽  
Ying Lu ◽  
Zhuo Li ◽  
Xiuwei Sun ◽  
Wanyu Zhang ◽  
...  
Keyword(s):  
Phosphonic Acid ◽  
Mechanochemical Synthesis ◽  
Metal Organic Framework ◽  
Sulfamic Acid ◽  
Proton Conduction ◽  
One Pot ◽  
Metal Organic ◽  
Aminomethyl Phosphonic Acid ◽  
Organic Framework

Through one-pot mechanochemical synthesis, a series of guests [imidazole, (Aminomethyl)phosphonic acid, urea and sulfamic acid] are rapidly encapsulated into the pores of MOF NENU-3 while MOF is formed, respectively. The...

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