Mixed-ligand copper(ii)–sulfonamide complexes: effect of the sulfonamide derivative on DNA binding, DNA cleavage, genotoxicity and anticancer activity

2013 ◽  
Vol 42 (28) ◽  
pp. 10244 ◽  
Author(s):  
Marta González-Álvarez ◽  
Alejandro Pascual-Álvarez ◽  
Lucas del Castillo Agudo ◽  
Alfonso Castiñeiras ◽  
Malva Liu-González ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Sulfonamide Derivative

Mixed-ligand Cu(II)–vanillin Schiff base complexes; effect of coligands on their DNA binding, DNA cleavage, SOD mimetic and anticancer activity

2013 ◽  
Vol 60 ◽  
pp. 216-232 ◽  
Author(s):  
Sartaj Tabassum ◽  
Samira Amir ◽  
Farukh Arjmand ◽  
Claudio Pettinari ◽  
Fabio Marchetti ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Complexes

Mixed ligand copper(II) complexes of 1,10-phenanthroline with tridentate phenolate/pyridyl/(benz)imidazolyl Schiff base ligands: Covalent vs non-covalent DNA binding, DNA cleavage and cytotoxicity

2014 ◽  
Vol 140 ◽  
pp. 255-268 ◽  
Author(s):  
Chandrasekaran Rajarajeswari ◽  
Mani Ganeshpandian ◽  
Mallayan Palaniandavar ◽  
Anvarbatcha Riyasdeen ◽  
Mohammad Abdulkadher Akbarsha
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Ligands

Mixed-ligand copper(ii) Schiff base complexes: the role of the co-ligand in DNA binding, DNA cleavage, protein binding and cytotoxicity

2016 ◽  
Vol 45 (22) ◽  
pp. 9073-9087 ◽  
Author(s):  
Wen-Jing Lian ◽  
Xin-Tian Wang ◽  
Cheng-Zhi Xie ◽  
He Tian ◽  
Xue-Qing Song ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Protein Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Complexes ◽  
Biological Features

Four novel mixed-ligand copper(ii) Schiff base complexes were synthesized and characterized. The biological features of the complexes and how acetic auxiliary ligands manipulate these features were investigated.

Synthesis, structure, DNA binding and anticancer activity of mixed ligand ruthenium(II) complex

2018 ◽  
Vol 1155 ◽  
pp. 288-296 ◽  
Author(s):  
Agnieszka Gilewska ◽  
Joanna Masternak ◽  
Katarzyna Kazimierczuk ◽  
Justyna Trynda ◽  
Joanna Wietrzyk ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Mixed Ligand

Four related mixed-ligand nickel(ii) complexes: effect of steric encumbrance on the structure, DNA/BSA binding, DNA cleavage and cytotoxicity

RSC Advances ◽  
2015 ◽  
Vol 5 (39) ◽  
pp. 30768-30779 ◽  
Author(s):  
Chun-Yan Gao ◽  
Zhong-Ying Ma ◽  
Yong-Po Zhang ◽  
Si-Tong Li ◽  
Wen Gu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Bsa Binding

Four new interrelated mixed-ligand nickel(ii) complexes have been synthesized and characterized. The activities of DNA binding/cleavage, BSA binding with complexes and the vitro cytotoxicity also have been explored.

Mixed-Ligand Copper(II)-phenolate Complexes:  Effect of Coligand on Enhanced DNA and Protein Binding, DNA Cleavage, and Anticancer Activity

2007 ◽  
Vol 46 (20) ◽  
pp. 8208-8221 ◽  
Author(s):  
Venugopal Rajendiran ◽  
Ramasamy Karthik ◽  
Mallayan Palaniandavar ◽  
Helen Stoeckli-Evans ◽  
Vaiyapuri Subbarayan Periasamy ◽  
...  
Keyword(s):  
Protein Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand

Mixed ligand copper(ii) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity

2015 ◽  
Vol 44 (22) ◽  
pp. 10210-10227 ◽  
Author(s):  
Rangasamy Loganathan ◽  
Sethu Ramakrishnan ◽  
Mani Ganeshpandian ◽  
Nattamai S. P. Bhuvanesh ◽  
Mallayan Palaniandavar ◽  
...  
Keyword(s):  
Dna Binding ◽  
Protein Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Double Strand Dna

Mixed ligand 5,6-dmp and 3,4,7,8-tmp complexes display more prominent cytotoxicity and higher apoptotic inducing ability.

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