scholarly journals Primary nucleation of salicylamide: the influence of process conditions and solvent on the metastable zone width

CrystEngComm ◽  
2013 ◽  
Vol 15 (36) ◽  
pp. 7285 ◽  
Author(s):  
Fredrik L. Nordström ◽  
Michael Svärd ◽  
Åke C. Rasmuson
Keyword(s):  
Process Conditions ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Primary Nucleation ◽  
Metastable Zone

Crystallization of Pentaerythritol I. Solubility, Density and Metastable Zone Width

1994 ◽  
Vol 59 (6) ◽  
pp. 1261-1269 ◽  
Author(s):  
Miloslav Karel ◽  
Jaroslav Nývlt ◽  
Angelo Chianese
Keyword(s):  
Aqueous Solutions ◽  
Nucleation Rate ◽  
Laboratory Experiments ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Kinetics Of Crystallization ◽  
Primary Nucleation ◽  
Metastable Zone ◽  
Width Measurements ◽  
Kinetics Of

Solubility of pentaerythritol in water has been determined using literature data, the polythermal method and the dry residue method. Densities of its aqueous solutions have been measured using a pycnometer. Kinetics of crystallization of the pentaerythritol has been determined in laboratory experiments. In this paper, metastable zone width measurements have been employed for the assessment of the primary nucleation rate.

scholarly journals The Metastability and Nucleation Thresholds of Ibuprofen in Ethanol and Water-Ethanol Mixtures

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Abdur Rashid ◽  
Edward T. White ◽  
Tony Howes ◽  
James D. Litster ◽  
Ivan Marziano
Keyword(s):  
Water Content ◽  
Propanoic Acid ◽  
Secondary Nucleation ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Primary Nucleation ◽  
Metastable Zone ◽  
The Times ◽  
Induction Times ◽  
Supersaturated Solutions

To investigate the crystallization of ibuprofen [((RS)-2-(4-(2-methylpropyl) phenyl) propanoic acid)] from ethanol and water-ethanol mixtures it is necessary to know the nucleation limits of its solutions. In the absence of crystals, nucleation will seldom occur below the PNT (primary nucleation threshold). If crystals are present, nucleation will seldom occur until below the lower SNT (secondary nucleation threshold). Below the SNT, crystals will still grow with negligible nucleation. PNT and SNT values (expressed as relative supersaturationσ) have been measured at 10, 25, and 40°C for ibuprofen in ethanol and in a range of mixtures of different ethanol (E)/water (W) ratios. The induction times were determined from observing the times to nucleate for a range of different supersaturated solutions at a given temperature andE/Wratio. As expected, lowering the supersaturation leads to longer induction times. In ethanol, the SNT values are small and thus the secondary metastable zone width (MSZW) is relatively narrow with a 1 h SNT relative supersaturation typically aboutσ~ 0.05. The 1 h PNT values are much larger with values forσaround 0.3. In aqueous ethanolic mixtures at 25°C, both the PNT and SNT decrease as the water content increases.

Determination of metastable zone width and the primary nucleation kinetics of sodium sulfate

2015 ◽  
Vol 49 (6) ◽  
pp. 869-876 ◽  
Author(s):  
Guisheng Zeng ◽  
Hui Li ◽  
Sheng Huang ◽  
Xianyong Wang ◽  
Junhong Chen
Keyword(s):  
Sodium Sulfate ◽  
Nucleation Kinetics ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Primary Nucleation ◽  
Metastable Zone ◽  
Kinetics Of

Effect of thermal history of aqueous solutions of KCl on the metastable zone width

1984 ◽  
Vol 49 (3) ◽  
pp. 559-569 ◽  
Author(s):  
Jaroslav Nývlt
Keyword(s):  
Aqueous Solution ◽  
Aqueous Solutions ◽  
Thermal History ◽  
Equilibrium Solubility ◽  
Metastable Zone Width ◽  
Zone Width ◽  
Preceding Experiment ◽  
History Of ◽  
Metastable Zone ◽  
The Given

The metastable zone width of an aqueous solution of KCI was measured as a function of the time and temperature of overheating above the equilibrium solubility temperature. It has been found that when the experiments follow close upon one another, the parameters of the preceding experiment affect the results of the experiment to follow.The results are interpreted in terms of hypotheses advanced in the literature to account for the effect of thermal history of solution. The plausibility and applicability of these hypotheses are assessed for the given cause of aqueous solution of a well soluble electrolyte.

Sign in / Sign up

Export Citation Format

Share Document