Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation

2014 ◽  
Vol 50 (40) ◽  
pp. 5388-5390 ◽  
Author(s):  
Michael J. Waring ◽  
David M. Andrews ◽  
Paul F. Faulder ◽  
Vikki Flemington ◽  
Jennifer C. McKelvie ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cancer Cell ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Signaling Cascade ◽  
Cancer Cell Proliferation ◽  
Type Iii ◽  
Phosphatidylinositol 4

scholarly journals Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0197372 ◽  
Author(s):  
Michael J. Thomenius ◽  
Jennifer Totman ◽  
Darren Harvey ◽  
Lorna H. Mitchell ◽  
Thomas V. Riera ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cancer Cell ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Cancer Cell Proliferation

OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis

2014 ◽  
Vol 50 (14) ◽  
pp. 2463-2477 ◽  
Author(s):  
Lucile Astorgues-Xerri ◽  
Maria E. Riveiro ◽  
Annemilaï Tijeras-Raballand ◽  
Maria Serova ◽  
Gabriel A. Rabinovich ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cancer Cell ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Cancer Cell Proliferation ◽  
Tumour Angiogenesis ◽  
Molecule Inhibitor

Inhibition of tankyrase by a novel small molecule significantly attenuates prostate cancer cell proliferation

2019 ◽  
Vol 443 ◽  
pp. 80-90 ◽  
Author(s):  
Honglin Cheng ◽  
Xin Li ◽  
Chuanlin Wang ◽  
Yujie Chen ◽  
Sijiang Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Small Molecule ◽  
Prostate Cancer Cell ◽  
Cancer Cell Proliferation

Discovery of potent, selective small molecule inhibitors of α-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIα)

2015 ◽  
Vol 25 (16) ◽  
pp. 3189-3193 ◽  
Author(s):  
Piotr Raubo ◽  
David M. Andrews ◽  
Jennifer C. McKelvie ◽  
Graeme R. Robb ◽  
James M. Smith ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Type Iii ◽  
Phosphatidylinositol 4

scholarly journals Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

2015 ◽  
Vol 7 (12) ◽  
pp. 968-979 ◽  
Author(s):  
Jing Wang ◽  
Cheng Luo ◽  
Changliang Shan ◽  
Qiancheng You ◽  
Junyan Lu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cancer Cell ◽  
Small Molecule ◽  
Cancer Cell Proliferation ◽  
Copper Trafficking
Sign in / Sign up

Export Citation Format

Share Document