Generation and characterization of airborne ethyl 2-cyanoacrylate atmospheres in a human whole-body exposure unit

2014 ◽  
Vol 6 (9) ◽  
pp. 3124-3132
Author(s):  
Christian Monsé ◽  
Jürgen Bünger ◽  
Thomas Brüning ◽  
Rolf Merget

Exposure to air contaminants, such as chemical vapors and particulate matter, poses important health hazards at workplaces.

2018 ◽  
Author(s):  
Xinze Peng ◽  
Mia R. Maltz ◽  
Jon K. Botthoff ◽  
Emma L. Aronson ◽  
Tara M. Nordgren ◽  
...  

Air pollution poses a significant threat to the environment and human health. Most in-vivo health studies conducted regarding air pollutants, including particulate matter (PM) and gas phase pollutants, have been either through traditional medical intranasal treatment or using a tiny chamber, which limit animal activities. In this study, we designed and tested a large, whole-body, multiple animal exposure chamber with uniform dispersion and exposure stability for animal studies. The chamber simultaneously controls particle size distribution and PM mass concentration. Two different methods were used to generate aerosol suspension through either soluble material (Alternaria extract), liquid particle suspension (Nanosilica solution) or dry powder (silica powder). We demonstrate that the chamber system provides well controlled and characterized whole animal exposures, where dosage is by inhalation of particulate matter.


Author(s):  
Aline Krindges ◽  
Vanusca Dalosto Jahno ◽  
Fernando Morisso

Incorporation studies of particles in different substrates with herbal assets growing. The objective of this work was the preparation and characterization of micro/nanoparticles containing cymbopogon nardus essential oil; and the incorporation of them on bacterial cellulose. For the development of the membranes was used the static culture medium and for the preparation of micro/nanoparticles was used the nanoprecipitation methodology. The incorporation of micro/nanoparticles was performed on samples of bacterial cellulose in wet and dry form. For the characterization of micro/nanoparticles were carried out analysis of SEM, zeta potential and particle size. For the verification of the incorporation of particulate matter in cellulose, analyses were conducted of SEM and FTIR. The results showed that it is possible the production and incorporation of micro/nanoparticles containing essential oil in bacterial cellulose membranes in wet form with ethanol.


2015 ◽  
Vol 92 ◽  
pp. 432-439 ◽  
Author(s):  
Marian Fe Theresa C. Lomboy ◽  
Leni L. Quirit ◽  
Victorio B. Molina ◽  
Godofreda V. Dalmacion ◽  
Joel D. Schwartz ◽  
...  

2001 ◽  
Vol 32 ◽  
pp. 353-354
Author(s):  
E. BRÜGGEMANN ◽  
T. GNAUK ◽  
K. MULLER ◽  
H. HERRMANN

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Vidya Chandrasekaran ◽  
Giada Carta ◽  
Daniel da Costa Pereira ◽  
Rajinder Gupta ◽  
Cormac Murphy ◽  
...  

AbstractThe renal proximal tubule is responsible for re-absorption of the majority of the glomerular filtrate and its proper function is necessary for whole-body homeostasis. Aging, certain diseases and chemical-induced toxicity are factors that contribute to proximal tubule injury and chronic kidney disease progression. To better understand these processes, it would be advantageous to generate renal tissues from human induced pluripotent stem cells (iPSC). Here, we report the differentiation and characterization of iPSC lines into proximal tubular-like cells (PTL). The protocol is a step wise exposure of small molecules and growth factors, including the GSK3 inhibitor (CHIR99021), the retinoic acid receptor activator (TTNPB), FGF9 and EGF, to drive iPSC to PTL via cell stages representing characteristics of early stages of renal development. Genome-wide RNA sequencing showed that PTL clustered within a kidney phenotype. PTL expressed proximal tubular-specific markers, including megalin (LRP2), showed a polarized phenotype, and were responsive to parathyroid hormone. PTL could take up albumin and exhibited ABCB1 transport activity. The phenotype was stable for up to 7 days and was maintained after passaging. This protocol will form the basis of an optimized strategy for molecular investigations using iPSC derived PTL.


2021 ◽  
Vol 96 ◽  
pp. 11-18 ◽  
Author(s):  
Yishu Xu ◽  
Xiaowei Liu ◽  
Jiuxin Qi ◽  
Tianpeng Zhang ◽  
Jingying Xu ◽  
...  

1996 ◽  
Vol 104 ◽  
pp. 687 ◽  
Author(s):  
K. Savela ◽  
M. J. Kohan ◽  
D. Walsh ◽  
F. P. Perera ◽  
K. Hemminki ◽  
...  

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