Biomolecular dual-ion-trap mass analyzer

The Analyst ◽  
2013 ◽  
Vol 138 (17) ◽  
pp. 4823 ◽  
Author(s):  
Yun-Fei Hsu ◽  
Jung-Lee Lin ◽  
Ming-Lee Chu ◽  
Chung-Hsuan Chen
Keyword(s):  
Ion Trap ◽  
Author(s):  
Fu-Xing XU ◽  
Liang WANG ◽  
Yuan-Yuan WANG ◽  
Chuan-Fan DING

2015 ◽  
Vol 26 (12) ◽  
pp. 2115-2124 ◽  
Author(s):  
Dragan Nikolić ◽  
Stojan M. Madzunkov ◽  
Murray R. Darrach

Separations ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 3 ◽  
Author(s):  
Benigno José Sieira ◽  
Inmaculada Carpinteiro ◽  
Rosario Rodil ◽  
José Benito Quintana ◽  
Rafael Cela

An analytical method based on high-resolution quadrupole–time-of-flight (QToF) mass spectrometry has been developed as an alternative to the classical method, using a low-resolution ion trap (IT) analyzer to reduce interferences in N-nitrosamines determination. Extraction of the targeted compounds was performed by solid-phase extraction (SPE) following the United States Environmental Protection Agency (USEPA) -521 method. First, both electron impact (EI) and positive chemical ionization (PCI) using methane as ionization gas were compared, along with IT and QToF detection. Then, parameters such as limits of detection (LOD) and quantification (LOQ), linearity, and repeatability were assessed. The results showed that the QToF mass analyzer combined with PCI was the best system for the determination of the N-nitrosamines, with instrumental LOD and LOQ in the ranges of 0.2–4 and 0.6–11 ng mL−1, respectively, which translated into method LOD and LOQ in the ranges of 0.2–1.3 and 0.6–3.9 ng L−1, respectively. The analysis of real samples showed the presence of 6 of the N-nitrosamines in influent, effluent, and tap water. N-nitrosodimethylamine (NDMA) was quantified in all the analyzed samples at concentrations between 1 and 27 ng L−1. Moreover, four additional nitrosamines were found in tap and wastewater samples.


2017 ◽  
Vol 421 ◽  
pp. 95-103
Author(s):  
Ailin Li ◽  
Jessica M. Higgs ◽  
Daniel E. Austin

2011 ◽  
Vol 299 (2-3) ◽  
pp. 151-157 ◽  
Author(s):  
Zhiping Zhang ◽  
Hannah Quist ◽  
Ying Peng ◽  
Brett J. Hansen ◽  
Junting Wang ◽  
...  

2009 ◽  
Vol 81 (12) ◽  
pp. 4840-4846 ◽  
Author(s):  
Xiaoxu Li ◽  
Gongyu Jiang ◽  
Chan Luo ◽  
Fuxing Xu ◽  
Yuanyuan Wang ◽  
...  

2012 ◽  
Vol 2 (4) ◽  
Author(s):  
Marija Ilić ◽  
Ljubica Svilar ◽  
Snežana Jovanović ◽  
Aleksandra Đorđević ◽  
Violeta Mitic ◽  
...  

Honey is well known in human diet and it is considered to be one of the healthiest foods with high nutritional value. Due to the growing presence of anthropogenic contaminants, with extremely long half-life and prevalence in all environments, some of them may be present in honey. Honey samples were spiked with six pesticides which are commonly used at the time of plant's blooming, in order to develop an efficient method for preparing honey samples for LC-MS-IT analysis. Samples of honey, spiked with soultion containing mixture of six pesticides (pirimicarb, atrazine, prometrine, malation, cyprodinil and famoxadone), were treated applying SPE with Florisil and C18 cartriges, as well as liquid-liquid extraction method. Afterwards, samples were injected in the HPLC with ESI ionisation source, and IT (ion trap) mass analyzer. Methanol solution of pesticides in the same concentrations as in spiked samples, were used as blank. In spiked honey samples, after treatment with Florisil prometrine and famoxadon were detected; with C18, atrazine and prometrine; after LLE famoxedon and pirimicarb. In the specific case, as acceptable sample preparation method SPE with Florisil cartridge may be proposed, since it enables reliable identification of the most examined pesticides. Key words: honey, pesticides, liquid chromatography, mass spectrometry, solid phase extraction


2020 ◽  
Author(s):  
Ifeoluwa Ayodeji ◽  
Nelson Rapalo Perdomo ◽  
Jacob T. Shelley ◽  
Theresa Evans-Nguyen

We demonstrate chemical noise filtration by differential mobility spectrometry (DMS) ahead of an ion trap mass analyzer. Use of DMS enables 10x improved accuracy in the isotope ratio measurement made for a sample of natural uranium.


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