Isotachophoresis with ionic spacer and two-stage separation for high sensitivity DNA hybridization assay

The Analyst ◽  
2013 ◽  
Vol 138 (11) ◽  
pp. 3117 ◽  
Author(s):  
Charbel Eid ◽  
Giancarlo Garcia-Schwarz ◽  
Juan G. Santiago
Keyword(s):  
Dna Hybridization ◽  
High Sensitivity ◽  
Hybridization Assay ◽  
Two Stage ◽  
Stage Separation

scholarly journals A two-stage amplified PZT sensor for monitoring lung and heart sounds in discharged pneumonia patients

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Hongbin Chen ◽  
Shuai Yu ◽  
Haiyang Liu ◽  
Jie Liu ◽  
Yongguang Xiao ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Cost Effective ◽  
High Ratio ◽  
Heart Sounds ◽  
Two Stage ◽  
Diagnosis And Prognosis ◽  
Sensor Device ◽  
Cost Effective Alternative ◽  
A Charge ◽  
Highly Sensitive Detection

AbstractAssessment of lung and heart states is of critical importance for patients with pneumonia. In this study, we present a small-sized and ultrasensitive accelerometer for continuous monitoring of lung and heart sounds to evaluate the lung and heart states of patients. Based on two-stage amplification, which consists of an asymmetric gapped cantilever and a charge amplifier, our accelerometer exhibited an extremely high ratio of sensitivity to noise compared with conventional structures. Our sensor achieves a high sensitivity of 9.2 V/g at frequencies less than 1000 Hz, making it suitable to use to monitor weak physiological signals, including heart and lung sounds. For the first time, lung injury, heart injury, and both lung and heart injuries in discharged pneumonia patients were revealed by our sensor device. Our sound sensor also successfully tracked the recovery course of the discharged pneumonia patients. Over time, the lung and heart states of the patients gradually improved after discharge. Our observations were in good agreement with clinical reports. Compared with conventional medical instruments, our sensor device provides rapid and highly sensitive detection of lung and heart sounds, which greatly helps in the evaluation of lung and heart states of pneumonia patients. This sensor provides a cost-effective alternative approach to the diagnosis and prognosis of pneumonia and has the potential for clinical and home-use health monitoring.

A rapid chemiluminescent DNA hybridization assay for the detection ofChlamydia trachomatis

1989 ◽  
Vol 4 (1) ◽  
pp. 357-366 ◽  
Author(s):  
J. M. Clyne ◽  
J. A. Running ◽  
M. Stempien ◽  
R. S. Stephens ◽  
H. Akhavan-Tafti ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Hybridization Assay ◽  
Ofchlamydia Trachomatis ◽  
Detection Ofchlamydia Trachomatis

A new two-stage separation procedure for the IDMS based quantification of low Pd and Pt amounts in automotive exhaust emissions

2015 ◽  
Vol 30 (2) ◽  
pp. 479-486 ◽  
Author(s):  
Jochen Vogl ◽  
Christian Meyer ◽  
Maren Koenig ◽  
Dorit Becker ◽  
Janine Noordmann ◽  
...  
Keyword(s):  
Exhaust Emissions ◽  
Separation Procedure ◽  
Automotive Exhaust ◽  
Two Stage ◽  
Effective Separation ◽  
Stage Separation

A two-step separation procedure for the IDMS-analysis of Pd and Pt was developed enabling effective separation from interfering elements.

scholarly journals The Antarctic Stratospheric Aerosol Observation and Sample-Return System Using Two-Stage Separation Method of a Balloon-Assisted Unmanned Aerial Vehicle

2021 ◽  
Author(s):  
Shin-Ichiro Higashino ◽  
Masahiko Hayashi ◽  
Takuya Okada ◽  
Shuji Nagasaki ◽  
Koichi Shiraishi ◽  
...  
Keyword(s):  
Control System ◽  
Unmanned Aerial Vehicle ◽  
Stratospheric Aerosol ◽  
Separation Method ◽  
Two Stage ◽  
Sample Return ◽  
Stage Separation ◽  
Rubber Balloon ◽  
Aerial Vehicle ◽  
The Antarctic

Abstract. The authors have developed a system for the Antarctic stratospheric aerosol observation and sample-return using the combination of a rubber balloon, a parachute, and a gliding fixed-wing unmanned aerial vehicle (UAV). A rubber balloon can usually reach 20 km to 30 km in altitude, but it becomes difficult for the UAV designed as a low-subsonic UAV to directly glide back from the stratospheric altitudes because the quantitative aerodynamic characteristics necessary for the control system design at such altitudes are difficult to obtain. In order to make the observation and sample-return possible at such higher altitudes while avoiding the problem with the control system of the UAV, the method using the two-stage separation was developed and attempted in Antarctica. In two-stage separation method, the UAV first descends by a parachute after separating from the balloon at stratospheric altitude to a certain altitude wherein the flight control system of the UAV works properly. Then it secondly separates the parachute for autonomous gliding back to the released point on the ground. The UAV in which an optical particle counter and an airborne aerosol sampler were installed was launched on January 24, 2015 from S17 (69.028S, 40.093E, 607 m MSL) near Syowa Station in Antarctica. The system reached 23 km in altitude and the UAV successfully returned aerosol samples. In this paper, the details of the UAV system using the two-stage separation method including the observation flight results, and the preliminary results of the observation and analyses of the samples are shown.

Rapid antiviral DNA-DNA hybridization assay for human cytomegalovirus

1990 ◽  
Vol 28 (3) ◽  
pp. 293-298 ◽  
Author(s):  
Wayne M. Dankner ◽  
David Scholl ◽  
Sylvia C. Stanat ◽  
Michael Martin ◽  
Robert L. Sonke ◽  
...  
Keyword(s):  
Human Cytomegalovirus ◽  
Dna Hybridization ◽  
Hybridization Assay

Search for muon to electron conversion at J-PARC: COMET experiment

2014 ◽  
Vol 31 ◽  
pp. 1460302 ◽  
Author(s):  
Y. Yuan ◽  
Keyword(s):  
Phase I ◽  
Charged Lepton ◽  
High Sensitivity ◽  
Electron Transition ◽  
Muonic Atom ◽  
Two Stage ◽  
Lepton Flavor ◽  
Electron Conversion ◽  
Very High

The COherent Muon to Electron Transition (COMET) experiment aims to search for the charged-lepton-flavor-violating process through measure muon to electron conversion in a muonic atom to very high sensitivity of 2.6 × 10-17. A two-stage approach in order to realize the experiment has been taken and the first-stage (COMET Phase-I) has been approved by KEK.

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