Structure and synthesis of 25-hydroxycholecalciferol-26,23-lactone, a metabolite of vitamin D3

1981 ◽  
pp. 424 ◽  
Author(s):  
David S. Morris ◽  
Dudley H. Williams ◽  
Alan F. Norris
Keyword(s):  
Vitamin D3 ◽  
25 Hydroxycholecalciferol

scholarly journals Productive performance of broiler breeder hens fed 25-hydroxycholecalciferol

2009 ◽  
Vol 38 (7) ◽  
pp. 1286-1290 ◽  
Author(s):  
Cibele Araujo Torres ◽  
Sergio Luiz Vieira ◽  
Renata Nuernberg Reis ◽  
André Klein Ferreira ◽  
Pedro Xavier da Silva ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Egg Production ◽  
Productive Performance ◽  
Broiler Breeder ◽  
Embryo Mortality ◽  
Breeder Hens ◽  
Randomized Design ◽  
Broiler Breeder Hens ◽  
Egg Shells ◽  
25 Hydroxycholecalciferol

An experiment was carried out with the objective of evaluating the addition of 25-hydroxycholecalciferol (25(OH) D3) in diets of broiler breeder hens. The experiment used Cobb 500 broiler breeder hens and was allotted to a complete randomized design with four treatments and eight replications of twenty females and two males each. The treatments consisted of vitamin premixes with 2,000 and 3,400 IU/kg diet vitamin D3 as the only source of vitamin or 2,000 IU D3 plus 35 or 69 mg/t of 25(OH) D3. Results of this experiment indicated that 25(OH) D3 had no significant effect on egg production parameters from 32 to 67 weeks. The supplementation of 25(OH) D3 resulted in better quality egg shells evaluated by the specific gravity at 60 weeks of age, regardless of the dosage. No significant differences were observed for hatchability of broiler breeder fertile eggs at 54 and 64 weeks. At 64 weeks, the hatch residue breakout showed less embryo mortality at the third week for treatments receiving 2,000 UI D3 in the diet and less embryo mortality at the second week of development from hens aged 67 weeks and supplemented with 2,000IU D3 and 2,000IU D3+ 69 mg 25(OH)D3. It was concluded that the supplementation with 25-hydroxycholecalciferol with cholecalciferol had similar effects as the diets with vitamin D3 as the only source on the productive performance of broiler breeder hens.

Effect of Phenobarbitone Treatment on Vitamin D Metabolism in Mammals

1974 ◽  
Vol 46 (4) ◽  
pp. 433-448 ◽  
Author(s):  
J. Silver ◽  
G. Neale ◽  
G. R. Thompson
Keyword(s):  
Vitamin D ◽  
Biological Activity ◽  
Silicic Acid ◽  
Vitamin D3 ◽  
Water Soluble ◽  
Prolonged Treatment ◽  
Vitamin D Metabolism ◽  
Silicic Acid Chromatography ◽  
Polar Metabolites ◽  
25 Hydroxycholecalciferol

1. The metabolism of radioactive cholecalciferol was studied in control and phenobarbitone-treated rats and pigs. 2. Treatment with phenobarbitone enhanced the appearance in plasma of 25-hydroxycholecalciferol (peak IV on silicic acid chromatography), and of more-polar metabolites (peak V), but not of the most-polar metabolites (peak VI). Peak IV had the chromatographic properties of authentic 25-hydroxycholecalciferol (25-HCC) and had biological activity. 3. There was no effect on the appearance of peaks V and VI in plasma after an injection of radioactive 25-HCC. 4. Treatment with phenobarbitone enhanced the excretion of metabolites of radioactive vitamin D3 in bile. These metabolites were largely water-soluble conjugates of peaks IV, V and VI, which included glucuronides. Peak IV in bile was not identical with 25-HCC. 5. Prolonged treatment with phenobarbitone depleted the tissue radioactivity of rats given radioactive vitamin D3.

scholarly journals Effects of source and level of in ovo-injected vitamin D3 on the hatchability and serum 25-hydroxycholecalciferol concentrations of Ross 708 broilers

2020 ◽  
Vol 99 (8) ◽  
pp. 3877-3884 ◽  
Author(s):  
S.A. Fatemi ◽  
K.E.C. Elliott ◽  
A. Bello ◽  
O.A. Durojaye ◽  
H. Zhang ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
In Ovo ◽  
25 Hydroxycholecalciferol

Phosphorus Deprivation: the Metabolism of Vitamin D3 and 25-Hydroxycholecalciferol in Rats

1972 ◽  
Vol 102 (2) ◽  
pp. 269-281 ◽  
Author(s):  
John G. Haddad ◽  
Vincenza Boisseau ◽  
Louis V. Avioli
Keyword(s):  
Vitamin D3 ◽  
Phosphorus Deprivation ◽  
25 Hydroxycholecalciferol
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