Hierarchical self-assembly of a β-amyloid peptide derivative

2013 ◽  
Vol 1 (5) ◽  
pp. 668-675 ◽  
Author(s):  
Si-Yong Qin ◽  
Yi Pei ◽  
Xiang-Ji Liu ◽  
Ren-Xi Zhuo ◽  
Xian-Zheng Zhang
Keyword(s):  
Self Assembly ◽  
Amyloid Peptide ◽  
Β Amyloid ◽  
Peptide Derivative ◽  
Β Amyloid Peptide

Preparation and Integration of Beta Amyloid Protein Nanofibers With Microfabricated Electrodes

2010 ◽  
Author(s):  
Nicola N. Kissoon ◽  
Andre´s D. Gutierrez ◽  
Anant K. Paravastu ◽  
Ongi Englander
Keyword(s):  
Self Assembly ◽  
Beta Amyloid ◽  
The Self ◽  
Amyloid Peptide ◽  
Amyloid Protein ◽  
Beta Amyloid Protein ◽  
Peptide Nanofibers ◽  
Multiple Electrodes ◽  
Β Amyloid ◽  
Β Amyloid Peptide

Micro and nano fabricated bio-systems and bio-devices can be produced once compatible processes for the integration of biomaterials and micro and nano systems are developed. Here, we demonstrate the integration of Alzheimer’s β-amyloid peptide nanofibers with metalized electrodes. The metalized electrodes and Alzheimer’s β-amyloid peptide nanofiber solutions are prepared separately. Metalized electrodes, composed of either chrome/gold or aluminum, with multiple electrodes are prepared using standard photolithography processes. Meanwhile, the Alzheimer’s β-amyloid peptide nanofiber solutions are prepared via the hydration of β-amyloid powder at various concentrations. The self-assembly of the β-amyloid nanofibers, to achieve well-dispersed networks, is optimized through periodic sonication and readdition of aliquots over timed intervals. The β-amyloid peptide solution can be successfully deposited onto the metalized electrodes to yield dense yet well-dispersed nanofiber arrays.

N2L, a novel lipoic acid-niacin dimer protects HT22 cells against β-amyloid peptide-induced damage through attenuating apoptosis

2019 ◽  
Vol 34 (6) ◽  
pp. 1761-1770 ◽  
Author(s):  
Rikang Wang ◽  
Lang Zhang ◽  
Rifang Liao ◽  
Qian Li ◽  
Rongbiao Pi ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Amyloid Peptide ◽  
Ht22 Cells ◽  
Β Amyloid ◽  
Β Amyloid Peptide

scholarly journals Mutagenic analysis of the nucleation propensity of oxidized Alzheimer's β-amyloid peptide

2005 ◽  
Vol 14 (8) ◽  
pp. 2125-2131 ◽  
Author(s):  
Tony Christopeit ◽  
Peter Hortschansky ◽  
Volker Schroeckh ◽  
Karlheinz Gührs ◽  
Giorgia Zandomeneghi ◽  
...  
Keyword(s):  
Amyloid Peptide ◽  
Β Amyloid ◽  
Β Amyloid Peptide

Inhibitors of Fibril Formation and Cytotoxicity of β-Amyloid Peptide Composed of KLVFF Recognition Element and Flexible Hydrophilic Disrupting Element

2002 ◽  
Vol 290 (1) ◽  
pp. 121-124 ◽  
Author(s):  
Ken-ichi Watanabe ◽  
Kazuhiko Nakamura ◽  
Shingo Akikusa ◽  
Tomoko Okada ◽  
Masato Kodaka ◽  
...  
Keyword(s):  
Fibril Formation ◽  
Amyloid Peptide ◽  
Recognition Element ◽  
Β Amyloid ◽  
Β Amyloid Peptide
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