Single line particle focusing induced by viscoelasticity of the suspending liquid: theory, experiments and simulations to design a micropipe flow-focuser

Lab on a Chip ◽  
2012 ◽  
Vol 12 (9) ◽  
pp. 1638 ◽  
Author(s):  
Gaetano D'Avino ◽  
Giovanni Romeo ◽  
Massimiliano M. Villone ◽  
Francesco Greco ◽  
Paolo A. Netti ◽  
...  
2014 ◽  
Vol 105 (19) ◽  
pp. 193507 ◽  
Author(s):  
Hoang V. Phan ◽  
Muhsincan Şeşen ◽  
Tuncay Alan ◽  
Adrian Neild

RSC Advances ◽  
2014 ◽  
Vol 4 (7) ◽  
pp. 3512-3520 ◽  
Author(s):  
Kyung Won Seo ◽  
Hyeok Jun Byeon ◽  
Hyung Kyu Huh ◽  
Sang Joon Lee

2011 ◽  
Vol 403-408 ◽  
pp. 482-485 ◽  
Author(s):  
Levent Trabzon ◽  
Huseyin Kizil ◽  
Levent Yobas ◽  
Arzu Ozbey ◽  
Mustafa Yilmaz ◽  
...  

We studied the effect of geometry on single focusing of particles in the passive microfluidic channels. There is a quantitative analysis of focusing on non-axisymmetric straight channels with two different unique designs as well as curved channels having symmetrical and asymmetrical radius of curvatures in one turn. We found that there is a clear relationship in existence of single line focusing with the degree of non-symmetry in microchannels. One-degree of asymmetry in straight channels does not induce any formation of single focusing, but single line focusing is pronounced by two-degree of asymmetry in straight channels. On the other hand, single line focusing in the curved channels is enhanced with asymmetrical radius of curvatures in one turn. The single line focusing in curved channels is seen at Rep values higher than 1, which gives us better continuous and high-throughput performance. The position of single focused particles in the microchannels is found to be 50 m with respect to the channel wall in the asymmetrical curved microchannels.


Author(s):  
Alan Boyde ◽  
Milan Hadravský ◽  
Mojmír Petran ◽  
Timothy F. Watson ◽  
Sheila J. Jones ◽  
...  

The principles of tandem scanning reflected light microscopy and the design of recent instruments are fully described elsewhere and here only briefly. The illuminating light is intercepted by a rotating aperture disc which lies in the intermediate focal plane of a standard LM objective. This device provides an array of separate scanning beams which light up corresponding patches in the plane of focus more intensely than out of focus layers. Reflected light from these patches is imaged on to a matching array of apertures on the opposite side of the same aperture disc and which are scanning in the focal plane of the eyepiece. An arrangement of mirrors converts the central symmetry of the disc into congruency, so that the array of apertures which chop the illuminating beam is identical with the array on the observation side. Thus both illumination and “detection” are scanned in tandem, giving rise to the name Tandem Scanning Microscope (TSM). The apertures are arranged on Archimedean spirals: each opposed pair scans a single line in the image.


Author(s):  
G. O. Hutchinson

A further passage shows the imagination and craft of Achilles Tatius taken to a still greater degree, as he depicts the hero Cleitophon at the terrible crisis of believing his beloved to be dead. The narrative is suspended as the writer develops, at remarkable length, a psychological and physiological observation on delayed effects. Where Heliodorus had heaped up imagery with abundance, Achilles develops with skilled organization a single line of thought and imagery, developing it and enriching it as he goes. Rhythm plays a vital part in this remarkable union of tight order and inventive imagination. The expansion and the deployment of science have a Plutarchan element; but the fantasy and the tautness create something quite different out of rhythm.


Meccanica ◽  
2021 ◽  
Author(s):  
I. Banerjee ◽  
M. E. Rosti ◽  
T. Kumar ◽  
L. Brandt ◽  
A. Russom

AbstractWe report a unique tuneable analogue trend in particle focusing in the laminar and weak viscoelastic regime of elasto-inertial flows. We observe experimentally that particles in circular cross-section microchannels can be tuned to any focusing bandwidths that lie between the “Segre-Silberberg annulus” and the centre of a circular microcapillary. We use direct numerical simulations to investigate this phenomenon and to understand how minute amounts of elasticity affect the focussing of particles at increasing flow rates. An Immersed Boundary Method is used to account for the presence of the particles and a FENE-P model is used to simulate the presence of polymers in a Non-Newtonian fluid. The numerical simulations study the dynamics and stability of finite size particles and are further used to analyse the particle behaviour at Reynolds numbers higher than what is allowed by the experimental setup. In particular, we are able to report the entire migration trajectories of the particles as they reach their final focussing positions and extend our predictions to other geometries such as the square cross section. We believe complex effects originate due to a combination of inertia and elasticity in the weakly viscoelastic regime, where neither inertia nor elasticity are able to mask each other’s effect completely, leading to a number of intermediate focusing positions. The present study provides a fundamental new understanding of particle focusing in weakly elastic and strongly inertial flows, whose findings can be exploited for potentially multiple microfluidics-based biological sorting applications.


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