Antioxidant activity and oxidative stress protection of duck proteins hydrolysates in SK-N-SH cells

2013 ◽  
Vol 4 (3) ◽  
pp. 476 ◽  
Author(s):  
Yuxing Guo ◽  
Daodong Pan ◽  
Zhen Wu ◽  
Chuanchuan Zhao ◽  
Jinxuan Cao
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Stress Protection ◽  
And Oxidative Stress ◽  
Oxidative Stress Protection

Structural Basis for Detoxification and Oxidative Stress Protection in Membranes

2006 ◽  
Vol 360 (5) ◽  
pp. 934-945 ◽  
Author(s):  
Peter J. Holm ◽  
Priyaranjan Bhakat ◽  
Caroline Jegerschöld ◽  
Nobuhiko Gyobu ◽  
Kaoru Mitsuoka ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Structural Basis ◽  
Stress Protection ◽  
And Oxidative Stress ◽  
Oxidative Stress Protection

Caveolin-1 promotes radioresistance in rhabdomyosarcoma through increased oxidative stress protection and DNA repair

2021 ◽  
Vol 505 ◽  
pp. 1-12
Author(s):  
Silvia Codenotti ◽  
Francesco Marampon ◽  
Luca Triggiani ◽  
Marco Lorenzo Bonù ◽  
Stefano Maria Magrini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Repair ◽  
Caveolin 1 ◽  
Stress Protection ◽  
Oxidative Stress Protection

scholarly journals Engineered EVs for Oxidative Stress Protection

2021 ◽  
Vol 14 (8) ◽  
pp. 703
Author(s):  
Anna Maria Tolomeo ◽  
Santina Quarta ◽  
Alessandra Biasiolo ◽  
Mariagrazia Ruvoletto ◽  
Michela Pozzobon ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Extracellular Vesicles ◽  
Transgene Expression ◽  
Hepatoma Cell ◽  
Serine Protease Inhibitor ◽  
Protein Product ◽  
Hepatoma Cell Line ◽  
Cytoprotective Activity ◽  
Stress Protection ◽  
Oxidative Stress Protection

Extracellular vesicles (EVs) are increasingly studied as vectors for drug delivery because they can transfer a variety of molecules across biological barriers. SerpinB3 is a serine protease inhibitor that has shown a protective anti-apoptotic function in a variety of stressful conditions. The aim of this study was to evaluate protection from oxidative stress-induced damage, using extracellular vesicles that overexpress SerpinB3 (EVs-SB3) in order to enhance the effect of extracellular vesicles on cellular homeostasis. EVs-SB3s were obtained from HepG2 cells engineered to overexpress SerpinB3 and they revealed significant proteomic changes, mostly characterized by a reduced expression of other proteins compared with EVs from non-engineered cells. These EV preparations showed a significantly higher protection from H2O2 induced oxidative stress in both the hepatoma cell line and in primary cardiomyocytes, compared to cells treated with naïve EVs or SerpinB3 alone, used at the same concentration. In conclusion, the induction of SerpinB3 transgene expression results in the secretion of EVs enriched with the protein product that exhibits enhanced cytoprotective activity, compared with naïve EVs or the nude SerpinB3 protein.

scholarly journals Antidiabetes and Antioxidant agents from Clausena excavata root as medicinal plant of Myanmar

2019 ◽  
Vol 17 (1) ◽  
pp. 1339-1344 ◽  
Author(s):  
T. M. Thant ◽  
N. S. Aminah ◽  
A. N. Kristanti ◽  
R. Ramadhan ◽  
H. T. Aung ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Medicinal Plant ◽  
Type Ii Diabetes Mellitus ◽  
Positive Control ◽  
Hypoglycemic Agents ◽  
Dual Function ◽  
Oral Hypoglycemic Agents ◽  
Antioxidant Agents ◽  
And Oxidative Stress

AbstractAll around the world, patients with diabetes and the prevalence of its disease are currently growing. Due to these side effects of oral hypoglycemic agents and oxidative stress in complicating diabetes, there is growing interest in drugs, which possess dual function as both type II diabetes mellitus treatment and oxidative stress treatment. The objective of this research is to search effective antidiabetes and antioxidant bioactive compounds from the Myanmar medicinal plant Clausena excavata. The root part of C. excavata was successfully extracted with 95% ethanol and followed by column chromatographic separation technique. The structure of isolated pure compounds was elucidated by using methods of spectroscopic such as UV-Vis, IR, NMR and HRFABMS spectrometry. The α-glucosidase inhibition assay was performed against baker’s yeast and rat intestine (sucrose and maltase) α-glucosidases. The activity of isolated compounds’ antioxidant was measured by using DPPH assay. Among the tested enzymes, the two isolated compounds, which were dentatin (1) and heptaphylline (2), exhibited highest inhibitory on maltase enzymes with IC50 values 6.75 and 11.46 μM; as positive control, acarbose (IC50, 2.35 μM) was utilized. Moreover, scavenging activity was found to be present upon seeing the result of antioxidant activity investigation of (1) and (2) (IC50 values 2.66 and 1.55 mM), where ascorbic acid (IC50 0.012 mM) was used as standard. Both compounds showed their antidiabetic and antioxidant activity with different fashion, especially exhibited strongest activity against on maltase α-glucosidase.

Dose–Response Effect of Tualang Honey on Postprandial Antioxidant Activity and Oxidative Stress in Female Athletes: A Pilot Study

2017 ◽  
Vol 23 (12) ◽  
pp. 989-995 ◽  
Author(s):  
Nur Syamsina Ahmad ◽  
Azlina Abdul Aziz ◽  
Kin Weng Kong ◽  
Mohamad Shariff A. Hamid ◽  
Jadeera Phaik Geok Cheong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Pilot Study ◽  
Dose Response ◽  
Female Athletes ◽  
Response Effect ◽  
Dose Response Effect ◽  
Tualang Honey ◽  
And Oxidative Stress

Alcohol-induced pancreatic oxidative stress: protection by phospholipid repletion

1999 ◽  
Vol 26 (5-6) ◽  
pp. 609-619 ◽  
Author(s):  
Semyon I. Aleynik ◽  
Maria Anna Leo ◽  
Maria K. Aleynik ◽  
Charles S. Lieber
Keyword(s):  
Oxidative Stress ◽  
Stress Protection ◽  
Oxidative Stress Protection
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