Enzyme-regulated unmodified gold nanoparticle aggregation: a label free colorimetric assay for rapid and sensitive detection of adenosine deaminase activity and inhibition

2012 ◽  
Vol 48 (89) ◽  
pp. 10996 ◽  
Author(s):  
Liangliang Zhang ◽  
Jingjin Zhao ◽  
Jianhui Jiang ◽  
Ruqin Yu
Keyword(s):  
Adenosine Deaminase ◽  
Gold Nanoparticle ◽  
Colorimetric Assay ◽  
Sensitive Detection ◽  
Label Free ◽  
Nanoparticle Aggregation ◽  
Gold Nanoparticle Aggregation ◽  
Adenosine Deaminase Activity

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

2016 ◽  
Vol 52 (22) ◽  
pp. 4167-4170 ◽  
Author(s):  
Chia-Chen Chang ◽  
Chie-Pein Chen ◽  
Chen-Yu Chen ◽  
Chii-Wann Lin
Keyword(s):  
Gold Nanoparticle ◽  
Label Free ◽  
Colorimetric Sensing ◽  
Base Stacking ◽  
Nanoparticle Aggregation ◽  
Protein Sensing ◽  
Sensing Platform ◽  
Dna Base ◽  
Gold Nanoparticle Aggregation ◽  
Catalytic Hairpin Assembly

A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy.

scholarly journals CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2

2021 ◽  
Author(s):  
Yiren Cao ◽  
Jinjun Wu ◽  
Bo Pang ◽  
Hongquan Zhang ◽  
X. Chris Le
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Detection ◽  
Isothermal Amplification ◽  
Nanoparticle Aggregation ◽  
Cleavage Activity ◽  
Gold Nanoparticle Aggregation

The trans-cleavage activity of the target-activated CRISPR-Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and...

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