Understanding (the lack of) homolytic substitution chemistry of sulfones

2012 ◽  
Vol 48 (67) ◽  
pp. 8326 ◽  
Author(s):  
Heather M. Aitken ◽  
Amber N. Hancock ◽  
Carl H. Schiesser
Keyword(s):  
Substitution Chemistry ◽  
Homolytic Substitution

ChemInform Abstract: Homolytic Substitution Chemistry: From James Franz to Antihypertensives

ChemInform ◽  
2012 ◽  
Vol 43 (30) ◽  
pp. no-no
Author(s):  
Sara H. Kyne ◽  
Heather M. Aitken ◽  
Sonia M. Horvart ◽  
Ching Yeh Lin ◽  
Michelle L. Coote ◽  
...  
Keyword(s):  
Substitution Chemistry ◽  
Homolytic Substitution

Is There a Homolytic Substitution Chemistry (SH2) of Sulfones?

2005 ◽  
Vol 70 (19) ◽  
pp. 7672-7678 ◽  
Author(s):  
David Crich ◽  
Thomas K. Hutton ◽  
Krishnakumar Ranganathan
Keyword(s):  
Substitution Chemistry ◽  
Homolytic Substitution

Synthesis of perfluoroalkylpyrroles by homolytic substitution with perfluoroalkyl radicals

1993 ◽  
Vol 34 (23) ◽  
pp. 3799-3800 ◽  
Author(s):  
Enrico Baciocchi ◽  
Ester Muraglia
Keyword(s):  
Homolytic Substitution

Synthesis of azaanthraquinones: homolytic substitution of pyridines

1982 ◽  
Vol 35 (7) ◽  
pp. 1451 ◽  
Author(s):  
DW Cameron ◽  
KR Deutscher ◽  
GI Feutrill ◽  
DE Hunt
Keyword(s):  
Ring Closure ◽  
Pyridine Derivatives ◽  
Derivatives Of ◽  
Substituted 1 ◽  
Homolytic Substitution

Synthesis of specific di- and tri-hydroxyazaanthraquinones by Friedel-Crafts procedures is limited by orientational ambiguity and by the lack of reactivity of pyridine derivatives in electrophilic acylation processes; however, suitable pyridines have been made to undergo radical benzoylation and benzylation at unsubstituted positions 2, 4 and 6. In particular, derivatives of pyridine-3-carbo-nitrile have been benzoylated at positions 2 and 4. Ring closure by intramolecular Houben-Hoesch reaction has then led to specifically substituted 1-and 2-azaanthraquinones and thence to the antibiotic bostrycoidin (1).

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