A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification

2012 ◽  
Vol 48 (47) ◽  
pp. 5895 ◽  
Author(s):  
Ki-Cheol Han ◽  
Eun Gyeong Yang ◽  
Dae-Ro Ahn
Keyword(s):  
Gold Nanoparticle ◽  
Signal Amplification ◽  
Multiplex Immunoassay ◽  
Highly Sensitive

A highly sensitive DNA sensor for attomolar detection of the BRCA1 gene: signal amplification with gold nanoparticle clusters

The Analyst ◽  
2015 ◽  
Vol 140 (8) ◽  
pp. 2713-2718 ◽  
Author(s):  
P. Abdul Rasheed ◽  
N. Sandhyarani
Keyword(s):  
Gold Nanoparticle ◽  
Signal Amplification ◽  
Brca1 Gene ◽  
Dna Sensor ◽  
Electrochemical Dna Sensor ◽  
Highly Sensitive ◽  
Nanoparticle Clusters

Gold nanoparticle clusters were successfully implemented signal amplification in an electrochemical DNA sensor.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

Highly sensitive lung cancer DNA detection via GO enhancing eATRP signal amplification

2021 ◽  
Vol 160 ◽  
pp. 105766
Author(s):  
Qianrui Liu ◽  
Jingliang Liu ◽  
Huaixia Yang ◽  
Xuchun Wang ◽  
Jinming Kong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Signal Amplification ◽  
Dna Detection ◽  
Highly Sensitive
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