The reaction of α-bromomethylchalcone with sodium hydrogen sulphide

1969 ◽  
Vol 0 (1) ◽  
pp. 5-5 ◽  
Author(s):  
Albert Padwa ◽  
Robert Gruber
Keyword(s):  
Hydrogen Sulphide ◽  
Sodium Hydrogen

Pyrimidine reactions. VIII. Methiodides formed from some dimethylaminopyrimidines

1965 ◽  
Vol 18 (2) ◽  
pp. 199 ◽  
Author(s):  
DJ Brown ◽  
T Teitei
Keyword(s):  
Nitrogen Atom ◽  
Methyl Iodide ◽  
Hydrogen Sulphide ◽  
Aqueous Ethanol ◽  
Alkaline Degradation ◽  
Dimethylamino Group ◽  
Nucleoside Synthesis ◽  
Sodium Hydrogen ◽  
Quaternary Compounds

4.Dimethylaminopyrimidine and its 2-chloro-, 2-dimethylamino-, 6-chloro-, 6-methylthio-, and 6-dimethylamino-derivatives are quaternized by methyl iodide at N 1. The structures of the resulting methiodides are proven by alkaline degradation to known oxopyrimidines. 4-Dimethylamino-2-(and 6-)methoxypyrimidine and 2-dimethylamino-4-methoxypyrimidine all undergo quaternization on a nuclear nitrogen atom followed by spontaneous loss of methyl iodide to yield oxopyrimidines (cf. the so-called Johnson and Hilbert nucleoside synthesis). The unique lability of the dimethylamino group in these quaternary compounds is exemplified in the con- version of 2-dimethylamino-1,6-dihydro-1,3-dimethyl-6-oxopyrimidinium iodide into 1,3-dimethyluracil by mere dissolution in water or aqueous ethanol, and by the reaction of 2,4-bisdimethylamino-I-methylpyrimidinium iodide with ethanolic sodium hydrogen sulphide to give 4-dimethylamino-1,2-dihydro-1-methyl-2-thio- pyrimidine.

Effects of hydrogen sulphide on heme oxigenase activity in TNBS induced colitis

2014 ◽  
Vol 52 (05) ◽  
Author(s):  
K Kupai ◽  
Z Szalai ◽  
M Korsós ◽  
Z Baráth ◽  
S Török ◽  
...  
Keyword(s):  
Hydrogen Sulphide
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