Synthesis, X-ray crystal structure, DNA binding, antioxidant and cytotoxicity studies of Ni(ii) and Pd(ii) thiosemicarbazone complexes

Metallomics ◽  
2012 ◽  
Vol 4 (2) ◽  
pp. 218-227 ◽  
Author(s):  
Eswaran Ramachandran ◽  
Palaniappan Kalaivani ◽  
Rathinasabapathi Prabhakaran ◽  
Nigam P. Rath ◽  
Selvaraj Brinda ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
X Ray ◽  
Cytotoxicity Studies ◽  
Thiosemicarbazone Complexes

Catecholase activity, DNA binding and cytotoxicity studies of a Cu(ii) complex of a pyridoxal schiff base: synthesis, X-ray crystal structure, spectroscopic, electrochemical and theoretical studies

RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 86851-86861 ◽  
Author(s):  
Piyali Adak ◽  
Bipinbihari Ghosh ◽  
Antonio Bauzá ◽  
Antonio Frontera ◽  
Alexander J. Blake ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Schiff Base ◽  
Dna Binding ◽  
Catalytic Efficiency ◽  
Theoretical Studies ◽  
X Ray ◽  
Cytotoxicity Studies ◽  
Catecholase Activity

A Cu(ii) complex, [Cu(L1Hpy)Cl]2(ClO4)2, of a tridentate pyridoxal Schiff base shows exceptionally high catalytic efficiency (kcat = 3.46 × 105 h−1) for catecholase activity in MeOH solution, the highest value reported in literature so far.

Synthesis, X-ray crystal structure, DNA/protein binding and cytotoxicity studies of five α-aminophosphonate N-derivatives

2016 ◽  
Vol 69 ◽  
pp. 132-139 ◽  
Author(s):  
Qingming Wang ◽  
Lei Yang ◽  
Hui Ding ◽  
Xuanrong Chen ◽  
Hua Wang ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Protein Binding ◽  
X Ray ◽  
Cytotoxicity Studies

Antitumor Activity, X-ray Crystal Structure, and DNA Binding Properties of Thiocoraline A, a Natural Bisintercalating Thiodepsipeptide

2007 ◽  
Vol 50 (14) ◽  
pp. 3322-3333 ◽  
Author(s):  
Ana Negri ◽  
Esther Marco ◽  
Verónica García-Hernández ◽  
Alberto Domingo ◽  
Antonio L. Llamas-Saiz ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Antitumor Activity ◽  
Binding Properties ◽  
X Ray ◽  
Dna Binding Properties

Two novel Ag(I) complexes of N-nicotinyl phosphoric triamide derivatives: Synthesis, X-ray crystal structure and in vitro antibacterial and cytotoxicity studies

2014 ◽  
Vol 423 ◽  
pp. 107-116 ◽  
Author(s):  
Khodayar Gholivand ◽  
Foroogh Molaei ◽  
Nasrin Oroujzadeh ◽  
Rezvan Mobasseri ◽  
Hossein Naderi-Manesh
Keyword(s):  
Crystal Structure ◽  
X Ray ◽  
Cytotoxicity Studies ◽  
Phosphoric Triamide

Response regulator YycF essential for bacterial growth: X-ray crystal structure of the DNA-binding domain and its PhoB-like DNA recognition motif

FEBS Letters ◽  
2008 ◽  
Vol 582 (23-24) ◽  
pp. 3434-3438 ◽  
Author(s):  
Toshihide Okajima ◽  
Akihiro Doi ◽  
Ario Okada ◽  
Yasuhiro Gotoh ◽  
Katsuyuki Tanizawa ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Bacterial Growth ◽  
Response Regulator ◽  
Dna Recognition ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
X Ray ◽  
Recognition Motif

ChemInform Abstract: The Synthesis and X-Ray Crystal Structure of the Monodentate (S) Thiosemicarbazide and Thiosemicarbazone Complexes (Fe(CO)2L(η5-C5H5))(PF6).

ChemInform ◽  
1990 ◽  
Vol 21 (2) ◽  
Author(s):  
M. J. M. CAMPBELL ◽  
E. MORRISON ◽  
V. ROGERS ◽  
P. K. BAKER ◽  
D. C. POVEY ◽  
...  
Keyword(s):  
Crystal Structure ◽  
X Ray ◽  
Thiosemicarbazone Complexes

The Dichloroplatinum(II) Complex of 5,5,7-Trimethyl-1,4-diazacycloheptane: Preparation, Crystal Structure and Binding to Nucleotides and DNA

1998 ◽  
Vol 51 (11) ◽  
pp. 977 ◽  
Author(s):  
Chih-Lynne Teo ◽  
Ronald R. Fenton ◽  
Peter Turner ◽  
Trevor W. Hambley
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Molecular Mechanics ◽  
X Ray Diffraction ◽  
Binding Studies ◽  
Triclinic Space Group ◽  
X Ray ◽  
Dna Binding Studies ◽  
Total Dna ◽  
R Value

The preparation of [Pt(tmdz)Cl2] (tmdz = 5,5,7-trimethyl-1,4-diazacycloheptane) is described. The crystal structure has been determined by X-ray diffraction methods and refined to an R value of 0·048 (764F). The crystals are triclinic, space group P -1, a 8·023(2), b 10·874(4), c 14·207(3) Å, α 95·34(3), β 94·96(2), γ 94·97(3)°. N.m.r. studies and molecular mechanics methods show that only one diastereomer of the complex—that observed in the crystal structure—is energetically accessible. In total DNA binding studies, [Pt(tmdz)Cl2] binds less effectively and at a lower rate than cisplatin. The complex reacts with dG and d(GpG) to form a variety of isomeric products, as indicated by h.p.l.c. analysis.

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